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Prednisolone and Glucose-6-phosphatase Activity in Liver Cells

Shin TS, Chung IH, Kim SS

Prednisolone, a cortisol analogue, was given intraperitoneally to rats with 5, 10 or 15 doses of 5 mg. per kg. of body weight per day. Sacrificing the animals 24 hours...
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Effects of Inonotus Obliqua Extract on Blood Glucose Levels in Genetically Diabetic Mice

Hong H

  • KMID: 2260570
  • Korean J Nutr.
  • 2007 Oct;40(7):601-605.
This study investigated the therapeutic effects of Inonotus obliqua extract on blood glucose, insulin, and other biochemical parameters in genetically diabetic mice (C57BL/KsJ-m+/+Lepr(db)). The mice were divided into four groups...
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A case of gout with glycogen storage disease type Ia

Kim HK, Yoon JY, Lee EY, Lee CK, Park JY, Yoo B, Moon HB

  • KMID: 2306109
  • Korean J Med.
  • 2002 Oct;63(4):421-425.
Glycogen storage disease type Ia (GSD-Ia) is an autosomal recessive disorder that has defects in glucose-6-phosphatase (G6Pase) in liver, kidney and intestinal mucosa. The defect leads to inadequate conversion of...
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Glucose-6-phosphatase Activity and Ultrastructures in Hepatocytes of Thioacetamide-treated Mice

Shin TS, Deung YK, Kim SS

To investigate the earlier cellular alterations(Glucose-6-Pase activity and morphologic features) caused by a hepatotoxin, thioacetamide (TAA), a single dose of the agent (200mg per kg of body weight) was given...
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A Case of von Gierke Disease

Joe YA, Song MY, Cho B, Lee SJ, Sung IK, Lee KS

  • KMID: 2335312
  • J Korean Pediatr Soc.
  • 1997 Dec;40(12):1756-1756.
von Gierke disease (type Ia glycogen storage disease) is an inherited disease associated with accumulation of glycogen in the liver, kidney, intestine and erythrocytes due to the defect of glucose-6-phosphatase...
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Sargassum coreanum extract alleviates hyperglycemia and improves insulin resistance in db/db diabetic mice

Park MH, Nam YH, Han JS

BACKGROUND/OBJECTIVES: The goal of this study was to examine the effect of Sargassum coreanum extract (SCE) on blood glucose concentration and insulin resistance in C57BL-KsJ-db/db mice. MATERIALS/METHODS: For 6 weeks, male...
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RBC Enzyme Analysis

Song J

  • KMID: 2049286
  • Clin Pediatr Hematol Oncol.
  • 2013 Apr;20(1):8-12.
Among ~20 RBC enzyme deficiencies causing hereditary hemolytic anemia (HRA), deficiencies involving three RBC enzymes such as glucose-6-phosphatase, pyruvate kinase and pyrimidine 5'-nucleodiase were known to be relatively common. The...
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Effects of Phytoestrogens on Glucose Metabolism in C57BL/KsOlaHsd-db/db Mice

Seo BH, Kim KO, Lee JH, Lee HS

This study was conducted to evaluate the antihyperglycemic effects of three phytoestrogens, genistein, coumestrol, and enterolactone, in type 2 diabetic animals. Forty male C57BL/KsOlaHsd-db/db mice were used as a diabetic...
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Gynura procumbens extract improves insulin sensitivity and suppresses hepatic gluconeogenesis in C57BL/KsJ-db/db mice

Choi SI, Lee HA, Han JS

BACKGROUND/OBJECTIVES: This study was designed to investigate whether Gynura procumbens extract (GPE) can improve insulin sensitivity and suppress hepatic glucose production in an animal model of type 2 diabetes. MATERIALS/METHODS: C57BL/Ksj-db/db...
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A case of multiple hepatic adenomas and gout with glycogen storage disease type Ia

Lee DG, Park SH, Choi JM, Seo JH, Lee JS, Yang MJ, Kim GT

  • KMID: 2081644
  • Korean J Med.
  • 2009 Apr;76(Suppl 1):S1-S5.
Glycogen storage disease (GSD) type Ia is a rare inherited metabolic disease characterized by glucose-6-phosphatase (G6Pase) deficiency, which results in many metabolic problems, such as fasting hypoglycemia, lactic acidosis, hyperuricemia,...
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A Case Report of Genetically Confirmed Glycogen Storage Disease type Ia

Yu KY, Noh SH, Hwang PH, Kim SJ

  • KMID: 1468163
  • J Korean Child Neurol Soc.
  • 2009 May;17(1):78-83.
Glycogen storage disease(GSD) type Ia is an autosomal recessive disease, caused by the absence or deficiency of glucose-6-phosphatase activity in the liver, kidney, and intestinal mucosa. Glucose-6-phosphatase is an essential...
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Effect of Fish Oil Diet on Activities of Lipogenic Enzymes and Glucose -6 -phosphatase in Rat Liver and Adipose

Jung SE

  • KMID: 1401868
  • J Nurs Acad Soc.
  • 1989 Dec;19(3):299-306.
In order to evaluate the effect of fish oil on lipid drogenase(G6PDH), malic enzyme (ME), glucose-6 -phosphatase (G6Pase) activities were measured in liver and adipose tissue of rats fed...
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Anesthetic Management for the Patient with Von Gierke`s Diseases

Choi YR, Choi YK, Kwon MI, Shin KI

  • KMID: 2240919
  • Korean J Anesthesiol.
  • 1981 Jun;14(2):198-203.
Glycogen storage disease is a rare metabolic disorder of significant to the anesthesiologist. The term "glycogen storage disease" is applied to a group of congenital and familial disorders characterised by...
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Effects of Dietary Proteins and Inositol Hexaphosphate on the Preneoplastic Lesions and Antioxidant Enzymes of Hepatocellular Carcinogenesis in Rats

Kim HD, Choi H

  • KMID: 2300782
  • Korean J Community Nutr.
  • 1999 Jun;4(2):239-247.
Six-week-old Sprague Dawley rats were fed the diets of 20% casein or soy protein. Two weeks after the feeding, hepatocellular chemical carcinogenesis was initiated by diethylnitrosamine(DEN), and promoted by the...
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A case of glycogen storage disease type Ia performed molecular genetic analysis

Lee HJ, Eun JR, Jang BI, Lee JH, Lee HW, Choi JH, Ki CS

  • KMID: 2256661
  • Korean J Med.
  • 2006 Jul;71(1):91-96.
Glycogen storage disease type Ia is caused by a deficiency of glucose-6-phosphatase (G6PC), which leads to glycogen accumulation in many organs including liver. We could diagnose a case of glycogen...
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Mutation Analysis of Korean Patients with Glycogen Storage Disease Type Ia

Kim JW, Park JY, Seo JK

  • KMID: 2275140
  • Korean J Pediatr Gastroenterol Nutr.
  • 2001 Sep;4(2):213-217.
PURPOSE: Glycogen storage disease type Ia (GSD Ia) is an autosomal recessive disorder of glycogen metabolism caused by glucose-6-phosphatase (G6Pase) deficiency. The clinical manifestations of G6Pase deficiency include growth retardation, hepatomegaly, hypoglycemia,...
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Clinical Findings of Genotypes in Korean Patients with Glycogen Storage Disease Type Ia

Ko JS, Yang HR, Kim JW, Seo JK

  • KMID: 1629583
  • Korean J Pediatr.
  • 2005 Aug;48(8):877-880.
PURPOSE: Glycogen storage disease type Ia (GSD Ia) is an autosomal recessive disorder caused by the deficiency of glucose-6-phosphatase (G6Pase). The aim of the study was to investigate the spectrum...
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Electron Microscopy on Activity and Localization of Glucose-6-phosphatase in Liver Cells

Shin TS, Chung IH, Kim SS

It is interesting and in important to study histochemical changes of glucose-6-phosphatase (G-6-Pase) activity by electron microscopy in order to promote the knowledge needed for diagnosis and prognosis in such...
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Uncooked Cornstarch Therapy in Type I Glycogen-Storage Disease (GSD-I)

Lee SY, Seo JK

  • KMID: 2208366
  • J Korean Pediatr Soc.
  • 1995 Jan;38(1):36-46.
OBJECTIVE: A few years ago it was shown that uncooked cornstarch feeding(UCS) could correct the biochemical abnormalities resulting from a deficiency of glucose-6-phosphatase in children with type ment. So far,...
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Anti-hyperglycemic effects and signaling mechanism of Perilla frutescens sprout extract

Kim DH, Kim SJ, Yu KY, Jeong SI, Kim SY

BACKGROUND/OBJECTIVES: Perilla frutescens (L.) Britton var. (PF) sprout is a plant of the labiate family. We have previously reported the protective effects of PF sprout extract on cytokine-induced β-cell damage....
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