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Direct protection of cultured neurons from ischemia-like injury by minocycline

Huang WC, Qiao Y, Xu L, Kacimi R, Sun X, Giffard RG, Yenari MA

Minocycline, a tetracycline antibiotic, is now known to protect cells via an anti-inflammatory mechanism. We further explored this effect using an in vitro model of ischemia-like injury to neurons. Coculturing...
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Human Papilloma Virus Type 16 E7 Genes Protect Astrocytes against Apoptotic and Necrotic Death Induced by Hydrogen Peroxide

Lee WT, Lee JE, Lee SH, Jang HS, Giffard RG, Park KA

Hydrogen peroxide is considered to be a dose- and time-dependent mediator in apoptotic and necrotic death. In this study, we examined the signaling of the E6 and E7 proteins with...
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