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Understanding asthma using animal models

Shin YS, Takeda K, Gelfand EW

Asthma is a complex syndrome with many clinical phenotypes in children and adults. Despite the rapidly increasing prevalence, clinical investigation and epidemiological studies of asthma, the successful introduction of new...
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Is There a Link Between Obesity and Asthma?

Kim SH, Sutherland ER, Gelfand EW

Increasing epidemiological data identify a link between obesity and asthma incidence and severity. Based on experimental data, it is possible that shared inflammatory mechanisms play a role in determining this...
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Immunomodulatory Effects of Ambroxol on Airway Hyperresponsiveness and Inflammation

Takeda K, Miyahara N, Matsubara , Taube C, Kitamura K, Hirano A, Tanimoto M, Gelfand EW

Ambroxol is used in COPD and asthma to increase mucociliary clearance and regulate surfactant levels, perhaps through anti-oxidant and anti-inflammatory activities. To determine the role and effect of ambroxol in...
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