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Anti-fibrotic treatments for chronic liver diseases: The present and the future

Odagiri N, Matsubara T, Sato-Matsubara M, Fujii H, Enomoto M, Kawada N

Liver fibrosis reflects tissue scarring in the liver due to the accumulation of excessive extracellular matrix in response to chronically persistent liver injury. Hepatocyte cell death can trigger capillarization of...
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Reliability Comparison between “Distal Radius and Ulna” and “Simplified Tanner–Whitehouse III” Assessments for Patients with Adolescent Idiopathic Scoliosis

Okuda A, Shigematsu H, Fujii H, Iwata E, Tanaka M, Morimoto Y, Masuda K, Yamamoto Y, Tanaka Y

Study Design: This is a retrospective clinical study. Purpose: In this study, we aim to evaluate the reliability of the distal radius and ulna assessment (DRU) and simplified Tanner-Whitehouse III classification...
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Adzuki bean (Vigna angularis) extract reduces amyloid-β aggregation and delays cognitive impairment in Drosophila models of Alzheimer's disease

Miyazaki H, Okamoto Y, Motoi A, Watanabe T, Katayama S, Kawahara S, Makabe H, Fujii H, Yonekura S

BACKGROUND/OBJECTIVES: Alzheimer's disease is a neurodegenerative disease that induces symptoms such as a decrease in motor function and cognitive impairment. Increases in the aggregation and deposition of amyloid beta protein...
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Protective role of oligonol from oxidative stress-induced inflammation in C6 glial cell

Ahn JH, Choi JW, Choi JM, Maeda T, Fujii H, Yokozawa T, Cho EJ

BACKGROUND/OBJECTIVES: Natural products or active components with a protective effect against oxidative stress have attracted significant attention for prevention and treatment of degenerative disease. Oligonol is a low molecular weight...
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