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Clinical Outcomes of Silk Patch in Acute Tympanic Membrane Perforation

Lee JH, Lee JS, Kim DK, Park CH, Lee HR

OBJECTIVES: The silk patch is a thin transparent patch that is produced from silk fibroin. In this study, we investigated the treatment effects of the silk patch in patients with...
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Protective Effect of Fibroin BF-7 on Neuronal Cell Death in Alzheimer Model using Amyloid beta Peptide

Lee DY, Yun JY, Kim JI, Kim DH, Han IS, Lee WB

  • KMID: 2092890
  • Korean J Anat.
  • 2007 Mar;40(1):57-67.
Factors such as senescence,stress and neurodegenerative diseases,including Alzheimer's disease, contribute to the impairment of organs,especially the brain.They also negatively affect normal brain functions such as memory and cognition.In this study,the...
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The bone regenerative effect of silk fibroin mixed with platelet-rich fibrin (PRF) in the calvaria defect of rabbit

Song JY, Kweon H, Kwon KJ, Park YW, Kim SG

INTRODUCTION: This study evaluated the bone regenerative effect of silk fibroin mixed with platelet-rich fibrin (PRF) of a bone defect in rabbits. MATERIALS AND METHODS: Ten New Zealand white rabbits were...
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The Effect of Silk Fibroin Particles Coated with Hydroxyapatites on Bone Regeneration in the Rat Calvarial Defect Model

Seok H, Park YT, Kim SG, Jin HJ

  • KMID: 1430801
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2013 Jan;35(1):13-17.
PURPOSE: This study evaluated the capability of bone formation of silk fibroin particles coated with hydroxyapatites (HA/SF), as bone graft material when put into the calvarial defect of rats. METHODS: Twenty...
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A comparative study for guided bone regeneration of silk fibroin nanomembrane(NanoGide-S(TM))

Han DH, Hong KS, Chung CH, Yim SB

  • KMID: 2321626
  • J Korean Acad Periodontol.
  • 2008 Sep;38(3):475-482.
PURPOSE: To evaluate the safety and efficiency of bone regenerative abilities of silk fibroin nanomembrane(Nanoguide-S) MATERIAL AND METHODS: The objects were 38 patients who had large defect at extraction sockets caused...
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Clinical study of guided bone regeneration of extracted socket with PLA/PGA membrane and silk fibroin membrane

Hwang WJ, Jeong SN, Kim YS, Pi SH, You HK, Chung CP, Shin HS

PURPOSE: This study was designed to compare the bond regeneratiom effects of treatment using silk fibroin membrane ( Nanogide-S (R)) resorbable barrier with control group treated by polyactic acid /...
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The Effect of Silk Fibroin-Alginic Acid Sponge Treatment as an Artificial Skin on Wound

Oh M, Choe J, Heo CY, Baik LM, Kim YS, Choi YW

  • KMID: 2098425
  • J Korean Soc Plast Reconstr Surg.
  • 2006 Jul;33(4):413-422.
PURPOSE: This study was designed to compare the wound healing effect of silk fibroin, alginate and fibroin/ alginate blend sponge with clinically used Nu gauze in a rat skin defect...
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The effect of silk fibroin and rhBMP-2 on bone regeneration in rat calvarial defect model

Nam JH, Noh KL, Pang EO, Yu WG, Kang ES, Kweon HY, Kim SG, Park YJ

  • KMID: 2328501
  • J Korean Assoc Oral Maxillofac Surg.
  • 2010 Oct;36(5):366-374.
INTRODUCTION: This study evaluated the capability of silk fibroin (SF) and recombinant human bone morphogenetic protein-2 loaded SF (SF-BMP) as a bone defect replacement matrix when grafted in a calvarial...
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The Effects of Tetracycline-loaded Silk Fibroin Membrane on Guided Bone Regeneration in a Rabbit Calvarial Defect Model

Lee SW, Park YT, Kim SG, Kweon HY, Jo YY, Lee HS

  • KMID: 1434388
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2012 Sep;34(5):293-298.
PURPOSE: The aim of this study was to evaluate the bone regeneration ability of 1% tetracycline (TC)-loaded silk fibroin membrane (SFM), in a rabbit calvarial defect model. METHODS: Twenty New Zealand...
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Preparation of Drug Eluting Natural Composite Scaffold Using Response Surface Methodology and Artificial Neural Network Approach

Shera SS, Sahu S, Banik RM

Silk fibroin/xanthan composite was investigated as a suitable biomedical material for controlled drug delivery, and blending ratios of silk fibroin and xanthan were optimized by response surface methodology (RSM) and...
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The Effect of Silk Fibroin/Nano-hydroxyapatite/Corn Starch Composite Porous Scaffold on Bone Regeneration in the Rabbit Calvarial Defect Model

Park YT, Kwon KJ, Park YW, Kim SG, Kim CW, Jo YY, Kweon HY, Kang SW

  • KMID: 2136926
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2011 Nov;33(6):459-466.
PURPOSE: This study evaluated the capability of bone formation with silk fibroin/nano-hydroxyapatite/corn starch composite scaffold as a bone defect replacement matrix when grafted in a calvarial bone defect of rabbits...
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Silk Fibroin and Substance P Combination Graft for the Reconstruction of a Bone Defect

Park KY, Choi KH, Park YJ, Song JY, Kim SG, Jo YY, Kweon HY, Kang SW

  • KMID: 2009670
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2011 Jul;33(4):293-300.
PURPOSE: Substance P is a well known neurotransmitter and has been known to mediate pain. Recently, it has been unveiled that substance P is involved in the recruitment of mesenchymal...
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Cell attachment and proliferation of osteoblast-like MG63 cells on silk fibroin membrane for guided bone regeneration

Yoo CK, Jeon JY, Kim YJ, Kim SG, Hwang KG

BACKGROUND: The aim of this study is to verify the feasibility of using silk fibroin (SF) as a potential membrane for guided bone regeneration (GBR). METHODS: Various cellular responses (i.e., cell...
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Dietary effect of silk protein on epidermal levels of free sphingoid bases and phosphate metabolites in NC/Nga mice

Kim Y, Song EH, Shin K, Lee Y, Cho Y

In our previous studies, dietary supplements of silk protein, sericin, and fibroin, were beneficial for improving epidermal levels of ceramides, which are the major lipids for maintaining the epidermal barrier....
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Sensitization to silk allergen among workers of silk filatures in India: a comparative study

Gowda G, Shivalingaiah AH, Vijayeendra AM, Sarkar N, Nagaraj C, Masthi NR

BACKGROUND: Sericulture plays an eminent role in development of rural economy in India. Silk filature is a unit where silk is unwound from the cocoons and the strands are collected...
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Carbon-Fiber Based Microelectrode Array Embedded with a Biodegradable Silk Support for In Vivo Neural Recording

Lee Y, Kong C, Chang JW, Jun SB

BACKGROUND: Recently, carbon fibers have been utilized to develop a depth-type microelectrode array for chronic neural recording. Since the diameter of carbon fibers is smaller than the conventional electrodes made...
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Electrospun Fibrous Silk Fibroin/Poly(L-Lactic Acid) Scaffold for Cartilage Tissue Engineering

Liu W, Li Z, Zheng L, Zhang X, Liu P, Yang T, Han B

For successful tissue engineering of articular cartilage, a scaffold with mechanical properties that match those of natural cartilage as closely as possible is needed. In the present study, we prepared...
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Comparable efficacy of silk fibroin with the collagen membranes for guided bone regeneration in rat calvarial defects

Kim JY, Yang BE, Ahn JH, Park SO, Shim HW

PURPOSE: Silk fibroin (SF) is a new degradable barrier membrane for guided bone regeneration (GBR) that can reduce the risk of pathogen transmission and the high costs associated with the...
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Fabrication and Characterization of Hydrocolloid Dressing with Silk Fibroin Nanoparticles for Wound Healing

Lee OJ, Kim JH, Moon BM, Chao JR, Yoon J, Ju HW, Lee JM, Park HJ, Kim DW, Kim SJ, Park HS, Park CH

Hydrocolloid dressings have been developed for many types of wound healing. In particular, dressing is a critical component in the successful recover of burn injuries, which causes a great number...
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Effect of Combination Graft of Choukroun's Platelet-rich-fibrin with Silk Fibroin Powder in the Peri-implant Defects

Jang ES, Lee HS, Lee HS, Lee HJ, Park KY, Park YW, Yoon YJ, Hong SM, Park JW

  • KMID: 1449183
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2011 Mar;33(2):103-111.
PURPOSE: Choukroun's platelet-rich-fibrin (PRF) is composed of platelets, white blood cells and fibrin matrix. It does not induce enough bone formation by itself but it can improve bone formation with...
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