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Soluble Epoxide Hydrolase Inhibitory Activity from Euphorbia supina Rafin

Luyen BT, Thao NP, Tai BH, Dat LD, Kim JE, Yang SY, Kwon SU, Lee YM, Kim YH

In our search for natural soluble epoxide hydrolase (sEH) inhibitors from plants, an extract of the dried whole plants of Euphorbia supina Rafin was found to significantly inhibit sEH activity...
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Morphometric and Histopathological Studies on the Effects of Some Chromatographic Fractions of Phyllanthus amarus and Euphorbia hirta on the Male Reproductive Organs of Rats

Adedapo AA, Abatan MO, Akinloye A, Idowu SO, Olorunsogo OO

  • KMID: 1089410
  • J Vet Sci.
  • 2003 Aug;4(2):181-185.
The aqueous crude extracts of P. amarus and E. hirta were administered to thirty eight-week old sexually mature male albino to determine the effects of these extracts on the male...
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The Resininferatoxin Therapy for the Hyperreflexive Neurogenic Bladder: Report of two cases of spinal cord injured patients

Park JH, Park GY, Lee BN, Sung JY

  • KMID: 2323807
  • J Korean Acad Rehabil Med.
  • 2003 Apr;27(2):275-279.
Resiniferatoxin, a substance isolated from some species of Euphorbia, a cactus-like plant, shows pharmacological effects similar to those of capsaicin. We administered resiniferatoxin for treating detrusor hyperreflexia to patient with...
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The Inhibitory Effect of Phytoclear-EL1 on Melanogenesis

Suh KS, Baek JW, Kim TK, Lee JW, Roh HJ, Jeon YS, Kim ST

BACKGROUND: Phytoclear-EL1, an extract from Euphorbia lathyris seeds, has a whitening effect due to inhibition of tyrosinase activity. OBJECTIVE: The purpose of this study was to investigate the inhibitory effect...
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Attenuation of RANKL-induced Osteoclast Formation via p38-mediated NFATc1 Signaling Pathways by Extract of Euphorbia Lathyris L

Kang JH, Lim H, Jeong JE, Yim M

BACKGROUND: Osteoclasts are the only cell type capable of breaking down bone matrix, and its excessive activation is responsible for the development of bone-destructive diseases. Euphorbia lathyris L. (ELL) is...
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Inhibition of p65 Nuclear Translocation by KIOM-79

Kim JS, Jang DS, Jeon YJ, You HJ, Park KH, Ming J, Moon HY, Yoon SP, Chang IY

  • KMID: 1937821
  • Korean J Anat.
  • 2006 Apr;39(2):103-110.
We demonstrate that KIOM-79, combined extracts isolated from Magnolia officinalis, Pueraria lobata, Glycyrrhiza uralensis, and Euphorbia pekinensis, inhibits LPS-induced expression of iNOS gene in RAW 264.7 cells. Treatment of RAW...
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The Effects of Peroxisome Proliferator Activated Receptor alpha (PPARalpha) Activator on Patients with Facial Erythema

Kim Y, Jung Y, Youm J, Park J, Bae YI, Park Y, Lee S

  • KMID: 2089032
  • Korean J Dermatol.
  • 2014 Sep;52(9):608-614.
BACKGROUND: Long-term use of topical steroids for inflammatory skin diseases can induce complications, and efforts to find a better treatment are being continued. Peroxisome proliferator activated receptor alpha (PPARalpha) suppresses...
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