- Sevoflurane with opioid or dexmedetomidine infusions in dogs undergoing intracranial surgery: a retrospective observational study
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Marquez-Grados F, Vettorato , Corletto F
- KMID: 2469023
- J Vet Sci.
- 2020 Jan;21(1):e8.
- doi: 10.4142/jvs.2020.21.e8
This study reports the clinical use of two sevoflurane-based anesthetic techniques in dogs undergoing craniectomy. Twenty-one animals undergoing elective rostrotentorial or transfrontal craniectomy for brain tumor excision, anesthetized with sevoflurane,... -
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- Dexmedetomidine as a non-triggering anesthetic agent in a patient with MELAS syndrome and systemic sepsis: A case report
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Kim SH, Park SY, Jung KT
- KMID: 2465339
- Anesth Pain Med.
- 2019 Oct;14(4):416-422.
- doi: 10.17085/apm.2019.14.4.416
BACKGROUND: The selection of anesthetic agents is important in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome patient because serious and unexpected complications can occur after anesthetic exposure. CASE:... -
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- Dexmedetomidine: present and future directions
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Lee S
- KMID: 2458316
- Korean J Anesthesiol.
- 2019 Aug;72(4):323-330.
- doi: 10.4097/kja.19259
Dexmedetomidine is a potent, highly selective α-2 adrenoceptor agonist, with sedative, analgesic, anxiolytic, sympatholytic, and opioid-sparing properties. Dexmedetomidine induces a unique sedative response, which shows an easy transition from sleep... -
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- The Effectiveness of Dexmedetomidine in Vacuum-Assisted Breast Biopsy Under Monitored Anesthesia Care
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Kim KW, Park JH, Kim S, Ahn EJ, Kim HJ, Choi HR, Chang YG, Bang SR
- KMID: 2451772
- Kosin Med J.
- 2019 Jun;34(1):24-29.
- doi: 10.7180/kmj.2019.34.1.24
OBJECTIVES: Vacuum-assisted breast biopsy (VABB) is a widely used technique for the diagnosis of breast lesions. It is carried out with local anesthesia, but procedural pain and stress are still... -
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- Sedation with dexmedetomidine in elderly patients during dental surgery: a retrospective case series
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Seto M, Kita R, Kondo S
- KMID: 2451322
- J Korean Assoc Oral Maxillofac Surg.
- 2019 Jun;45(3):152-157.
- doi: 10.5125/jkaoms.2019.45.3.152
OBJECTIVES: The number of elderly patients with systemic basal disease requiring invasive dental treatment has increased. Appropriate prediction of surgical invasiveness and combined use of psychosedation are thought to contribute... -
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- Fatal pulmonary aspiration during balanced sedation with dexmedetomidine and midazolam: A case report
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Park JH, Kim SY, Kwon MA
- KMID: 2447976
- Anesth Pain Med.
- 2019 Apr;14(2):236-240.
- doi: 10.17085/apm.2019.14.2.236
Recently, balanced sedation has commonly been used during procedural sedation. Dexmedetomidine is known for its relative safety to cause “conscious sedation†with little respiratory depression but has some limitations such... -
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- Effects of Dexmedetomidine Infusion During Sevoflurane Anesthesia on Otoacoustic Emissions
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Åžahin MÄ, Vural A, Akın A, Ketenci Ä, Ãœnlü Y
- KMID: 2447579
- J Audiol Otol.
- 2019 Apr;23(2):89-95.
- doi: 10.7874/jao.2018.00311
BACKGROUND AND OBJECTIVES: Knowing the ototoxic potential of the agents used in medical treatments is important for the protection of hearing. Although we have knowledge regarding some effects of dexmedetomidine,... -
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- Dexmedetomidine and propofol sedation requirements in an autistic rat model
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Elmorsy SA, Soliman GF, Rashed LA, Elgendy H
- KMID: 2447512
- Korean J Anesthesiol.
- 2019 Apr;72(2):169-177.
- doi: 10.4097/kja.d.18.00005
BACKGROUND: Autism is a challenging neurodevelopmental disorder. Previous clinical observations have suggested altered sedation requirements for children with autism. Our study aimed to test this observation experimentally in an animal... -
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- The correlation of heart rate between natural sleep and dexmedetomidine sedation
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Kang D, Lim C, Shim DJ, Kim H, Kim JW, Chung HJ, Shin Y, Kim JD, Ryu SJ
- KMID: 2447511
- Korean J Anesthesiol.
- 2019 Apr;72(2):164-168.
- doi: 10.4097/kja.d.18.00208
BACKGROUND: Sedation by dexmedetomidine, like natural sleep, often causes bradycardia. We explored the nature of heart rate (HR) changes as they occur during natural sleep versus those occurring during dexmedetomidine... -
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- Role of dexmedetomidine in pediatric dental sedation
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Mohite V, Baliga S, Thosar N, Rathi N
- KMID: 2444752
- J Dent Anesth Pain Med.
- 2019 Apr;19(2):83-90.
- doi: 10.17245/jdapm.2019.19.2.83
Dexmedetomidine is a highly selective α2-adrenoceptor agonist with a vast array of properties, making it suitable for sedation in numerous clinical scenarios. Its use was previously restricted to the sedation... -
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- Effects of preanesthetic single administration of dexmedetomidine on the remifentanil and propofol requirement during laparoscopic cholecystectomy
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Park H, Kim HS, Kim JW, Lee GG, Park DH, Jeong CY, Park SG, Ryu KH
- KMID: 2434195
- Anesth Pain Med.
- 2019 Jan;14(1):29-34.
- doi: 10.17085/apm.2019.14.1.29
BACKGROUND: Dexmedetomidine, an α2-adrenergic agonist, can be used for sedation and as an adjuvant to anesthetics. This study aimed to evaluate the effects of preanesthetic administration of dexmedetomidine on the... -
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- Fluid loading during spinal anesthesia can reduce bradycardia after intravenous dexmedetomidine infusion
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Lee W, Han Y, Lim SH, Moon SH, Cho K, Kim MH
- KMID: 2434194
- Anesth Pain Med.
- 2019 Jan;14(1):19-28.
- doi: 10.17085/apm.2019.14.1.19
BACKGROUND: Dexmedetomidine has been widely used during spinal anesthesia to provide sedation. However, dexmedetomidine frequently causes significant bradycardia. This study was designed to evaluate whether fluid loading could reduce the... -
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- Dexmedetomidine Ameliorates Sleep Deprivation-Induced Depressive Behaviors in Mice
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Moon EJ, Ko IG, Kim SE, Jin JJ, Hwang L, Kim CJ, An H, Lee BJ, Yi JW
- KMID: 2426692
- Int Neurourol J.
- 2018 Oct;22(Suppl 3):S139-S146.
- doi: 10.5213/inj.1836228.114
PURPOSE: Sleep deprivation induces depressive symptoms. Dexmedetomidine is a α2-adrenoreceptor agonist and this drug possesses sedative, anxiolytic, analgesic, and anesthetic-sparing effect. In this study, the action of dexmedetomidine on sleep... -
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- Dexmedetomidine Attenuates Neuropathic Pain by Inhibiting P2X7R Expression and ERK Phosphorylation in Rats
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Lin JP, Chen CQ, Huang LE, Li NN, Yang Y, Zhu SM, Yao YX
- KMID: 2419336
- Exp Neurobiol.
- 2018 Aug;27(4):267-276.
- doi: 10.5607/en.2018.27.4.267
α2-Adrenoceptor agonists attenuate hypersensitivity under neuropathic conditions. However, the mechanisms underlying this attenuation remain largely unknown. In the present study, we explored the potential roles of purinergic receptor 7 (P2X7R)/extracellular... -
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- The effects of loading dose administration rate of dexmedetomidine on sedation and dexmedetomidine requirement in elderly patients undergoing spinal anesthesia
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Kung HC, Cheng CC, Kang DH, Jeong HJ, Shin YS, Kim DS, Ryu SJ, Kim KH, Kim JD
- KMID: 2436033
- Anesth Pain Med.
- 2018 Jul;13(3):264-270.
- doi: 10.17085/apm.2018.13.3.264
BACKGROUND: This study evaluated the effect of decrease in loading dose administration rate of dexmedetomidine (DMT) on sedation and DMT requirement in elderly patients. METHODS: Fifty-eight patients over 65 years old... -
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- Ultrasound-guided superficial cervical plexus block under dexmedetomidine sedation versus general anesthesia for carotid endarterectomy: a retrospective pilot study
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Do W, Cho AR, Kim EJ, Kim HJ, Kim E, Lee HJ
- KMID: 2415733
- Yeungnam Univ J Med.
- 2018 Jun;35(1):45-53.
- doi: 10.12701/yujm.2018.35.1.45
BACKGROUND: Carotid endarterectomy (CEA) has been performed under regional and general anesthesia (GA). The general anesthesia versus local anesthesia for carotid surgery study compared the two techniques and concluded that... -
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- Postoperative infusion of a low dose of dexmedetomidine reduces intravenous consumption of sufentanil in patient-controlled analgesia
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Kweon DE, Koo Y, Lee S, Chung K, Ahn S, Park C
- KMID: 2413533
- Korean J Anesthesiol.
- 2018 Jun;71(3):226-231.
- doi: 10.4097/kja.d.18.27056
BACKGROUND: Combining adjunctive medications with patient-controlled analgesia (PCA) has been used to minimize opioid related side-effects. The aim of this study was to evaluate whether postoperative infusion of a sub-sedative... -
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- Blunting effect of dexmedetomidine on transient cardiovascular changes induced by inhalation of desflurane: a randomized controlled trial
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Jang MS, Han JH, Park SJ, Oh ID, Ahn SE, Choi JH
- KMID: 2437422
- Anesth Pain Med.
- 2018 Apr;13(2):158-164.
- doi: 10.17085/apm.2018.13.2.158
BACKGROUND: A rapid increase in desflurane concentration has been demonstrated to induce transient sympathetic hyperactivity and lead to increases in blood pressure and heart rate (HR). Additionally, the use of... -
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- Beneficial aspect of dexmedetomidine as a postoperative sedative for cardiac surgery
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Kim S, Kim KM, Lee S, Yoo BH, Kim S, Park SJ, Lee J, Chung E
- KMID: 2436058
- Anesth Pain Med.
- 2018 Jan;13(1):65-71.
- doi: 10.17085/apm.2018.13.1.65
BACKGROUND: The aim of this study was to compare the clinical outcomes of the sedative, analgesic, and hemodynamic effects of dexmedetomidine and midazolam for sedation after coronary artery bypass grafting... -
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- Pre-anesthetic sedative effect of dexmedetomidine in laparoscopic cholecystectomy performed under general anesthesia
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Kim JW, Lee HL, Park JS, Kim JH, Ryu KH
- KMID: 2436051
- Anesth Pain Med.
- 2018 Jan;13(1):23-29.
- doi: 10.17085/apm.2018.13.1.23
BACKGROUND: This study evaluated the effects of pre-anesthetic administration of dexmedetomidine on sedative, cardiovascular, and recovery parameters. METHODS: This was a prospective, randomized, double-blind, placebo-controlled study. We selected 60 patients who... -
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