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Influence of Phenilamine on Pressor Responses of Norepinephrine and Tyramine

Kim WS, Jung JW, Jang KS, Hong SP, Cho KK, Choi CH, Lim DY

The effect of Pheniramine(Avil), a histaminergic-1 receptor blocking agent presently employed in treating various allergic diseases on pressor actions of norepinephring(NE) and tyramine (TR) was studied in the rabbit. Pheniramine,...
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Amitriptyline, Desipramine, and Paroxetine Inhibit Nitric Oxide Production in Primary Schwann Cell Cultures of Rats

Lim YJ, Kim HJ, Park HS, Kim SH, Lee SC, Ham BM, Kim YC, Cheong IY

BACKGROUND: Antidepressants are being used as supplemental therapy in neuropathic and inflammatory pain. The mechanism of their inhibitory effect on experimental animal inflammation is not clear. Studies...
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Changes in c-Fos Expression in the Forced Swimming Test: Common and Distinct Modulation in Rat Brain by Desipramine and Citalopram

Choi SH, Chung S, Cho JH, Cho YH, Kim JW, Kim JM, Kim HJ, Kim HJ, Shin KH

Rodents exposed to a 15-min pretest swim in the forced swimming test (FST) exhibit prolonged immobility in a subsequent 5-min test swim, and antidepressant treatment before the test swim reduces...
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Chronic Antidepressant Administration Increases the Expression of PhosphoCREB(Phosphorylated Cyclic AMP Response Element Binding Protein) in Rat Hippocampus

Kim SY, Han JH, Lee CU, Paik IH

  • KMID: 2340212
  • J Korean Neuropsychiatr Assoc.
  • 1998 Sep;37(5):992-998.
OBJECTIVES: This study designed to assess the expression of phosphoCREB in rat hippocampus after chronic administration of various antidepressants in comparison with chronic administration of antipsychotic and antianxiety drugs. METHODS: Male...
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Regional differences in the levels of biogenic amines and their metabolites in rat brain after tricyclic antidepressant treatments

Chung MY, Kim DG, Yoo KJ, Hong SS

Changes in the levels of biogenic amines in different brain regions and the cerebrospinal fluid in rats were measured after acute or chronic treatment with tricyclic antidepressants. After single or...
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An Autoradiographic Study on the Rat Neostriatal Dopamine Receptor Changes after 6-hydroxydopamine Injection into the Medial Prefrontal Cortex

Kwon JS, Lee DY, Woo JI

  • KMID: 2340296
  • J Korean Neuropsychiatr Assoc.
  • 1999 Mar;38(2):408-418.
The frontal cortex of rat is innervated by dopaminergic pathway(mesocortical pathway) arising from ventral tegmental area. Several studies have suggested that mesocortical dopaminergic neurons may modulate the function of dopaminergic...
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Noradrenergic Changes in an Experimental Model of Parkinsonism Using 6-hydroxydopamine

Jeon BS

  • KMID: 2342515
  • J Korean Neurol Assoc.
  • 1996 Jun;14(2):448-454.
BACKGROUND & OBJECTIVE: Stereotaxic injection of 6-hydroxydopamine(6OHDA) into the ventral midbrain is the most commonly used Parkinsonian animal model. In the presence of norepinephrine(NE) uptake blockers, 6OHDA is believed to...
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Effects of Central Dopaminergic Receptor-Activation on the Cardiovascular System

Kim SM, Park YK, Lee SS, Ko CM

  • KMID: 1957399
  • J Korean Neurol Assoc.
  • 1992 Sep;10(3):308-315.
The central dopaminergic receptor is believed to suppress the cardiovascular system So it may be involved in the blood pressure regulation But, it's action is still controversial. Furthermore, the mechanisms...
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Effects of Various Tricyclic Antidepressants on Contractile Response of the Rat Vas Deferens to Electrical Stimulation of Hypogastric Nerve

Yum SH, Seo KK, Kim SC

  • KMID: 1885000
  • Korean J Urol.
  • 2001 Jul;42(7):749-754.
PURPOSE: To compare the inhibitory effects of various tricyclic antidepressants (TCAs) on contractile response of the rat vas deferens to electrical stimulation of hypogastric nerve. MATERIALS AND METHODS: A total of...
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DEVELOPMENT OF A PAIN ASSESSMENTMODEL ANDEFFETS OF ANTIDEPRESSANTS ON NOCICEPTIVEJAWOPENING REFLEX IN FREE MOVING RATS

Park JY, Lee SH, An DG

  • KMID: 2190562
  • J Korean Assoc Oral Maxillofac Surg.
  • 1998 Jul;24(3):280-289.
The purpose of the present was devalopment of a new pain assessment model that recorded in free moving rats to eliminte of anesthetic agents in orofacial area. Antinociceptive effects and...
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Intracisternal antidepressants suppressed the nociceptive jaw opening reflex in freely moving rats

Ahn DK, Kim YS

  • KMID: 1849838
  • Korean J Physiol Pharmacol.
  • 1998 Jun;2(3):307-312.
This study was performed to investigate the mechanism of central analgesic effects of antidepressants. Thirty four male rats were anesthetized with pentobarbital sodium (40 mg/kg, ip). A stainless steel guide cannula and a...
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