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Activation-induced Cytidine Deaminase in B Cell Immunity and Cancers

Park SR

Activation-induced cytidine deaminase (AID) is an enzyme that is predominantly expressed in germinal center B cells and plays a pivotal role in immunoglobulin class switch recombination and somatic hypermutation for...
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Curcumin modulates the apolipoprotein B mRNA editing by coordinating the expression of cytidine deamination to uridine editosome components in primary mouse hepatocytes

He P, Tian N

Curcumin, an active ingredient of Curcuma longa L., can reduce the concentration of low-density lipoproteins in plasma, in different ways. We had first reported that curcumin exhibits hypocholesterolemic properties by...
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Perfusion Patterns of Ischemic Stroke on Computed Tomography Perfusion

Lin L, Bivard A, Parsons MW

  • KMID: 2094555
  • J Stroke.
  • 2013 Sep;15(3):164-173.
CT perfusion (CTP) has been applied increasingly in research of ischemic stroke. However, in clinical practice, it is still a relatively new technology. For neurologists and radiologists, the challenge is...
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Antifungal Activity of the Extract from Paeonia japonica against Candida albicans

Seong I

  • KMID: 1513659
  • Korean J Med Mycol.
  • 2006 Mar;11(1):19-26.
BACKGROUND: Candida albicans is one of the normal flora of the skin, mucous membranes and gastrointestinal tract. Vaginal candidiasis remains a significant problem in women of childbearing age, majority of...
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Effect of Recombinant Human Growth Hormone Add on Therapy on Acute Stroke Outcome

Jin GH, Lee JB

Recombinant human growth hormone (rhGH) administration stimulate the secretion of the brain insulin-like growth factor-1 (IGF-1) concentration and IGF-1 is a pleiotropic neurotropic peptide to exert beneficial effect for the...
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The Protective Effect of Mannitol and Methylprednisolone in the Acute Focal Cerebral Ischemia in Cats

Shin KM

It is the purpose of the this experimental study to investigate the protective effect of pretreatment of mannitol and methylprednisolone(MP) on the changes of the high-energy metabolites(nucleotides ; derivatives of...
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Concomitant AID Expression and BCL7A Loss Associates With Accelerated Phase Progression and Imatinib Resistance in Chronic Myeloid Leukemia

Yu N, Shin S, Choi JR, Kim Y, Lee KA

No abstract available.
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Establishment and identification of cell lines from type O blood Korean native pigs and their efficiency in supporting embryonic development via somatic cell nuclear transfer

Taweechaipaisankul A, Kim GA, Jin JX, Yeom SC, Lee BC

Due to their similarities with humans in anatomy, physiology, and genetics miniature pigs are becoming an attractive model for biomedical research. We aim to establish and evaluate blood type O...
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Molecular Pathogenesis of Gastric Cancer

Park WS

In this article, I will survey the major genetic susceptibility and somatic genetic alterations involved in gastric cancer and adenoma. These include germline and somatic genetic alterations in oncogenes, tumor...
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The Relationship between Clinical Drug Sensitivity and Expression of Drug Resistance Genes in Patients with Acute Myelogenous Leukemia

Kim KW, Kim HJ, Park SY

  • KMID: 1832115
  • Korean J Hematol.
  • 2001 May;36(2):115-122.
BACKGROUND: The occurrence of drug resistance (DR) is one of the obstacles in the successful chemotherapeutic treatment of cancer. Multidrug resistance-1 (MDR-1), multidrug resistance associated protein (MRP), topoisomerase IIalpha (Topo...
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Evaluation of Vestibulo-spinal Reflex Using Modified Romberg Test

Park HM, Kim YH, Park GH, Rhee CK, Choi JE

  • KMID: 2074237
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Apr;44(4):366-369.
BACKGROUND AND OBJECTIVES: The Romberg test is a simple, inexpensive modality to test the vestibulo-spinal reflex. However, it is not a quantitative measure and has low sensitivity and specificity. We...
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Carpal Tunnel Syndrome Diagnosed by Carpal Tunnel Pressure Measurement

Ahn SY, Chung YS, Lee SH, Son YJ, Yang HJ

  • KMID: 2288407
  • Korean J Spine.
  • 2009 Sep;6(3):225-227.
Carpal tunnel syndrome(CTS), the most common compressive neuropathy, is usually diagnosed by clinical features and nerve conduction test(NCS). However, NCS might show no abnormal finding. Ultrasonography(USG), known as helpful adjunctive...
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Computerized Dynamic Posturography to Detect Unsteadiness in Aged Patients with Large-Fiber Peripheral Neuropathy

Lee GH

  • KMID: 2015098
  • J Korean Geriatr Soc.
  • 2003 Sep;7(3):222-229.
BACKGROUND: Large-fiber peripheral neuropathy is prevalent in the elderly and risk of falling is higher in patients with it. This study`s aim is to see if, using computerized dynamic posturography(CDP),...
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The Therapeutic Effect of Sauchinone on Inflammatory Arthritis in Mice

Jung SM, Lee J, Lee J, Baek SY, Park SH, Kwok SK

OBJECTIVE: Rheumatoid arthritis (RA) is a chronic inflammatory disease, mainly involving joints and bones. Sauchinone is an anti-inflammatory agent isolated from Saururus chinensis, which was used in oriental medicine. The...
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Pressure Measurement in Carpal Tunnel Syndrome : Correlation with Electrodiagnostic and Ultrasonographic Findings

Ahn SY, Hong YH, Koh YH, Chung YS, Lee SH, Yang HJ

OBJECTIVE: This study was done to evaluate the correlation between carpal tunnel pressure (CTP), electrodiagnostic and ultrasonographic findings in patients with carpal tunnel syndrome (CTS). METHODS: CTP was measured during...
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Interleukin-17 Enhances Germinal Center Formation and Immunoglobulin G1 Production in Mice

Lee J, Lee SY, Kang CM, Jhun JY, Kim JH, Cho ML, Park SH, Kim HY, Kwok SK

OBJECTIVE: Interleukin (IL)-17 is a pro-inflammatory cytokine that has pleiotropic effects on multiple target cells and thereby contributes to the development of immune-mediated inflammatory disorders. However, the role of IL-17...
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The Effects of Antiepileptic Drugs on Balance in Older People

Lee GH

  • KMID: 2185061
  • J Korean Neurol Assoc.
  • 2008 Aug;26(3):186-193.
BACKGROUND: The purpose of this study was to quantitatively assess the subclinical balance dysfunction in elderly people taking antiepileptic drugs. METHODS: We recruited sixty-three patients who were at least 50 years...
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Comparison Study of Outcomes of Deceased Donor Liver Transplantation before and after Korean Model for End-Stage Liver Disease (MELD) System: Single Center Experience

Lee JA, Choi GS, Kim JM, Kwon CH, Joh JW

BACKGROUND: In June of 2016, the Model for End-Stage Liver Disease (MELD)-based allocation system replaced the Child-Turcotte-Pugh (CTP) score-based system for deceased donor liver transplantation (DDLT) in Korea. This study...
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Comparison of Diagnostic Usefulness of Multi-Channel CT Perfusion and Conventional Brain CT in the Acute Pontine Infarct

Kim SA, Lee MS, Kim MS, Kim YJ

  • KMID: 2322605
  • J Korean Soc Radiol.
  • 2013 Jan;68(1):9-16.
PURPOSE: CT perfusion (CTP) is an important modality in the diagnosis of acute stroke, and the range of its use is gradually expanding from supratentorial to whole brain stroke. We...
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Correlation between Berg Balance Scale and Sensory Organization Test of Computerized Dynamic Posturography in Brain Injured Patients

Jung HY, Kim MO, Kwak JR

  • KMID: 2323620
  • J Korean Acad Rehabil Med.
  • 2001 Jun;25(3):404-411.
OBJECTIVE: To examine the correlation between Berg balance scale (BBS) which is tool for assessing the clinical balance function and sensory organization test (SOT) of computerized dynamic posturography (CDP) in...
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