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Cyclooxygenase-2 Expression Is Related to the Epithelial-to-Mesenchymal Transition in Human Colon Cancers

Jang TJ, Jeon KH, Jung KH

PURPOSE: Down-regulation of E-cadherin is a hallmark of the epithelial-to-mesenchymal transition (EMT). EMT progression in cancer cells is associated with the loss of certain epithelial markers and the acquisition of...
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Chemopreventive and metabolic effects of inulin on colon cancer development

Hijova E, Szabadosova V, Stofilova , Hrckova G

Prebiotics modulate microbial composition and ensure a healthy gastrointestinal tract environment that can prevent colon cancer development. These natural dietary compounds are therefore potential chemopreventive agents. Thirty Sprague-Dawley rats (4...
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Probiotics may Reduce Inflammation by Enhancing Peroxisome Proliferator Activated Receptor gamma Activation in HT-29 Cells

Eun CS, Han DS, Lee SH, Jeon YC, Sohn JH, Kim YS, Lee J

  • KMID: 782835
  • Korean J Gastroenterol.
  • 2007 Mar;49(3):139-146.
BACKGROUND/AIMS: The peroxisome proliferator-activated receptor gamma (PPARgamma) is a nuclear receptor highly expressed in the colon which plays an anti-inflammatory role through the inhibition of nuclear factor-kappaB (NF-kappaB) pathway. Probiotics...
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