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Detection of Mitochondrial ATP-Sensitive Potassium Channels in Rat Cardiomyocytes

Cuong DV, Kim N, Kim E, Lee Y, Kim H, Kang S, Hur DY, Joo H, Park YS, Hong YG, Lee S, Chung J, Seog D, Han J

  • KMID: 1611347
  • Korean J Physiol Pharmacol.
  • 2004 Aug;8(4):201-206.
Mitochondrial ATP-sensitive potassium (mitoKATP) channels play a role in early and late ischemic preconditioning. Nevertheless, the subunit composition of mitoKATP channels remains unclear. In this study, we investigated the subunit...
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Identification of a Marker Protein for Cardiac Ischemia and Reperfusion Injury by Two-Dimensional Gel Electrophoresis and Matrix-Assisted Laser Desorption Ionization Mass Spectrometry

Lee Y, Kim N, Kim H, Joo H, Kim Y, Jeong D, Cuong DV, Kim E, Hur DY, Park YS, Hong YG, Lee S, Chung J, Seog D, Han J

  • KMID: 1611348
  • Korean J Physiol Pharmacol.
  • 2004 Aug;8(4):207-211.
The purpose of the present study was to evaluate the expression of cardiac marker protein in rabbit cardiac tissue that was exposed to ischemic preconditioning (IPC), or ischemiareperfusion injury (IR)...
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Mitochondrial calcium uniporter inhibition attenuates mouse bone marrow-derived mast cell degranulation induced by beta-1,3-glucan

Cuong DV, Kim HK, Marquez J, Kim N, Ko KS, Rhee BD, Han J

Mast cells are primary mediators of allergic inflammation. Beta-1,3-glucan (BG) protects against infection and shock by activating immune cells. Activation of the BG receptor induces an increase in intracellular Ca2+,...
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Regional Differences in Mitochondrial Anti-oxidant State during Ischemic Preconditioning in Rat Heart

Thu VT, Cuong DV, Kim N, Youm JB, Warda M, Park WS, Ko JH, Kim E, Han J

  • KMID: 1512908
  • Korean J Physiol Pharmacol.
  • 2007 Apr;11(2):57-64.
Ischemic preconditioning (IPC) is known to protect the heart against ischemia/reperfusion (IR)-induced injuries, and regional differences in the mitochondrial antioxidant state during IR or IPC may promote the death or...
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Thiol-dependent Redox Mechanisms in the Modification of ATP-Sensitive Potassium Channels in Rabbit Ventricular Myocytes

Han J, Kim N, Cuong DV, Kim C, Kim E

  • KMID: 1607349
  • Korean J Physiol Pharmacol.
  • 2003 Feb;7(1):15-23.
Cellular redox state is known to be perturbed during ischemia and that Ca2+ and K+ channels have been shown to have functional thiol groups. In this study, the properties of...
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Changes of Cytosolic Ca2+ under Metabolic Inhibition in Isolated Rat Ventricular Myocytes

Kang S, Kim N, Joo H, Youm JB, Park WS, Warda M, Kim H, Cuong DV, Kim T, Kim E, Han J

  • KMID: 1600112
  • Korean J Physiol Pharmacol.
  • 2005 Oct;9(5):291-298.
To characterize cytosolic Ca2+ fluctuations under metabolic inhibition, rat ventricular myocytes were exposed to 200microM 2, 4-dinitrophenol (DNP), and mitochondrial Ca2+, mitochondrial membrane potential (delta psi m), and cytosolic Ca2+...
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Nitric Oxide-cGMP-Protein Kinase G Pathway Contributes to Cardioprotective Effects of ATP-Sensitive K+ Channels in Rat Hearts

Cuong DV, Kim N, Cho HC, Kim E, Han J

  • KMID: 1611234
  • Korean J Physiol Pharmacol.
  • 2004 Apr;8(2):95-100.
Ischemic preconditioning (IPC) has been accepted as a heart protection phenomenon against ischemia and reperfusion (I/R) injury. The activation of ATP-sensitive potassium (KATP) channels and the release of myocardial nitric...
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Inhibition of DNA-dependent Protein Kinase by Blocking Interaction between Ku Complex and Catalytic Subunit of DNA-dependent Protein Kinase

Kim CH, Cuong DV, Kim JS, Kim N, Kim E, Han J

  • KMID: 1607348
  • Korean J Physiol Pharmacol.
  • 2003 Feb;7(1):9-14.
Recent studies indicated that cancer cells become resistant to ionizing radiation (IR) and chemotherapy drugs by enhanced DNA repair of the lesions. Therefore, it is expected to increase the killing...
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