- Increasing the alpha 2, 6 Sialylation of Glycoproteins May Contribute to Metastatic Spread and Therapeutic Resistance in Colorectal Cancer
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Park JJ, Lee M
- KMID: 1712321
- Gut Liver.
- 2013 Nov;7(6):629-641.
Abnormal glycosylation due to dysregulated glycosyltransferases and glycosidases is a key phenomenon of many malignancies, including colorectal cancer (CRC). In particular, increased ST6 Gal I (beta-galactoside alpha 2, 6 sialyltransferase)... -
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- Reduced E-Cadherin Expression as a Cause of Distinctive Signet-Ring Cell Variant in Colorectal Carcinoma
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Kim HC, Kim HJ, Kim JC
- KMID: 2157589
- J Korean Med Sci.
- 2002 Feb;17(1):23-28.
- doi: 10.3346/jkms.2002.17.1.23
Colorectal signet-ring cell carcinoma (SRCC) is a rare type of adenocarcinoma and presents with distinctive clinicopathological features. This study was performed to assess the biological characteristics of colorectal SRCC regarding... -
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- Expression of Cyclooxygenase-2 and its Relationship to p53 Accumulation in Colorectal Cancers
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Lim SC, Lee TB, Choi CH, Ryu SY, Kim KJ, Min YD
- KMID: 724106
- Yonsei Med J.
- 2007 Jun;48(3):495-501.
- doi: 10.3349/ymj.2007.48.3.495
PURPOSE: Cyclooxygenase (COX)-2 is an inducible isoform responsive to cytokines, mitogens, and growth factors, and is believed to be an important enzyme related to colorectal cancer (CRC). Existing evidence suggests... -
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- Coexpression of MUC1 with p53 or MUC2 correlates with Lymph Node Metastasis in Colorectal Carcinomas
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Jang KT, Chae SW, Sohn JH, Park HR, Shin HS
- KMID: 2157590
- J Korean Med Sci.
- 2002 Feb;17(1):29-33.
- doi: 10.3346/jkms.2002.17.1.29
The alteration of the mucin profile have been known to play a role in colorectal carcinogenesis. MUC1 is up-regulated and MUC2 is down-regulated in colorectalcarcinomas. Overexpression of p53 is frequently... -
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- Expression of Cdx2 Protein in Colorectal Cancer
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Pack JH, Kim TD, Oh HA, Lee EJ, Kim JW, Jang BI, Kim TN, Jung MK, Bae YK
- KMID: 935212
- Korean J Gastroenterol.
- 2005 Sep;46(3):204-210.
BACKGROUND/AIMS: The caudal-related homeobox transcription factor, Cdx2, plays an important role in proliferation and differentiation of intestinal epithelial cells. Its expression is confined to normal and neoplastic intestinal epithelium. We... -
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