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Long-term Outcome of Incision and Curettage Treatment in Patients with Lacrimal Gland Ductulitis

An J, Lee K

PURPOSE: To describe the effects and long-term outcomes of incision and curettage treatment in patients with lacrimal gland ductulitis. METHODS: Twenty-four patients (24 eyes) with lacrimal gland ductulitis who were treated...
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A novel compound heterozygous mutation in DNAH5 in a Korean neonate with primary ciliary dyskinesia

Lee NW, Jeong JE, Jang YY, Chung HL

Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disease affecting motile cilia. A female neonate was hospitalized with respiratory distress 72 hours after birth and showed concurrent situs inversus. She...
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Interplay Between Primary Cilia and Autophagy and Its Controversial Roles in Cancer

Ko JY, Lee EJ, Park JH

Primary cilia and autophagy are two distinct nutrient-sensing machineries required for maintaining intracellular energy homeostasis, either via signal transduction or recycling of macromolecules from cargo breakdown, respectively. Potential correlations between...
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Influence of Intranasal Drugs on Human Nasal Mucociliary Clearance and Ciliary Beat Frequency

Jiao J, Zhang L

The nasal mucociliary clearance system, which comprises epithelial cilia and mucus from goblet cells, is an important intrinsic defense mechanism of the upper respiratory tract. Intranasal drugs and additives can...
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Repeated restraint stress promotes hippocampal neuronal cell ciliogenesis and proliferation in mice

Lee K, Ko HW

Stress severely disturbs physiological and mental homeostasis which includes adult neurogenesis in hippocampus. Neurogenesis in hippocampus is a key feature to adapt to environmental changes and highly regulated by multiple...
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The First Case of Diarrhoea in Tibetan Sheep, Ovis aries, Caused by Balantidium coli in the Qinghai Tibetan Plateau Area, China

Jian YN, Wang GP, Li XP, Zhang XY, Ma LQ

This study was carried out to determine the pathogen-causing diarrhoea in sheep Ovis aries in the Qinghai Tibetan Plateau Area, China. A trophozoite was identified as species of ciliate alveolates...
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Can Tissue Cilia Lengths and Urine Cilia Proteins Be Markers of Kidney Diseases?

Park KM

The primary cilium is an organelle which consists of a microtubule in the core and a surrounding cilia membrane, and has long been recognized as a “vestigial organelle”. However, new...
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Primary Cilia as a Signaling Platform for Control of Energy Metabolism

Song DK, Choi JH, Kim MS

Obesity has become a common healthcare problem worldwide. Cilia are tiny hair-like organelles on the cell surface that are generated and anchored by the basal body. Non-motile primary cilia have...
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Morphology of cat vomeronasal organ non-sensory epithelium during postnatal development

Elgayar SA, Saad-Eldin HM, Haussein O

The vomeronasal organ has an important role in mammal's social and sexual behaviours. In addition, it mediates defensive behavior through detection of protein pheromone homologues. In this work, a detailed...
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Spatial Allocation and Specification of Cardiomyocytes during Zebrafish Embryogenesis

Fukui H, Chiba A, Miyazaki T, Takano H, Ishikawa H, Omori T, Mochiuzki

Incomplete development and severe malformation of the heart result in miscarriage of embryos because of its malfunction as a pump for circulation. During cardiogenesis, development of the heart is precisely...
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Correction of Diffuse Trichiasis Using Eyelid Margin Splitting Combined with Cilia Rotation Suture

Na M, Park T, Lee K

PURPOSE: In the present study, we introduced and evaluated the effectiveness of eyelid margin splitting combined with cilia rotation suture performed in simplified steps resulting in minimized complications in diffuse...
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The Healing Effects of Autologous Mucosal Grafts in Experimentally Injured Rabbit Maxillary Sinuses

Topdag M, Kara A, Konuk E, Demir N, Ozturk M, Calıskan , Topdag DO, Ulubil A, Keskin IG, Iseri M

OBJECTIVES: Healing processes of the nose and paranasal sinuses are quite complex, and poorly understood. In this study, we aimed to compare the effect of mucosal autologous grafts on the...
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Alternative Method for Primary Nasal Epithelial Cell Culture Using Intranasal Brushing and Feasibility for the Study of Epithelial Functions in Allergic Rhinitis

Park DY, Kim S, Kim CH, Yoon JH, Kim HJ

PURPOSE: Although differentiated normal human nasal epithelial (NHNE) cells can be used to study the role of human nasal epithelium, there is a need for effective culture models of nasal...
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A Case Report of Eyebrow Basal Cell Carcinoma Successfully Treated with 5% Imiquimod Cream

Kang BS, Kim NJ, Choung HK, Khwarg SI

PURPOSE: Basal cell carcinoma is the most common malignant neoplasm of the skin. Periorbital basal cell carcinoma needs to be treated for cosmetic improvement and prevention of intraorbital invasion. Although...
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Autophagy Regulates Formation of Primary Cilia in Mefloquine-Treated Cells

Shin JH, Bae DJ, Kim ES, Kim HB, Park SJ, Jo YK, Jo DS, Jo DG, Kim SY, Cho DH

Primary cilia have critical roles in coordinating multiple cellular signaling pathways. Dysregulation of primary cilia is implicated in various ciliopathies. To identify specific regulators of autophagy, we screened chemical libraries...
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Nephronophthisis

Kang HG, Cheong HI

NPHP is the most common monogenic cause of CKD in children or adolescents. Extra-renal symptoms often accompany, therefore examination of retina, hearing, and skeleton is necessary in patients with CKD...
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Quickert Suture Using Nonabsorbable Suture Material for Lower Lid Entropion

Ko YJ, Kim HC

PURPOSE: To introduce the modified Quickert suture for lower lid entropion, using nonabsorbable suture material. METHODS: From October, 2011 to June, 2012, a total of 11 patients (12 eyes) with lower...
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Interplay of Signaling Molecules in Olfactory Sensory Neuron toward Signal Amplification

Pervez N, Ham HG, Kim S

Over the last decades, piles of data have been accumulated to understand the olfactory sensation in every aspect, ranging from the intracellular signaling to cognitive perception. This review focuses on...
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Effects of Topical Intranasal Doxycycline Treatment in the Rat Allergic Rhinitis Model

Avincsal M, Ozbal S, Ikiz AO, Pekcetin C, Guneri EA

  • KMID: 2278383
  • Clin Exp Otorhinolaryngol.
  • 2014 Jun;7(2):106-111.
OBJECTIVES: Allergic rhinitis (AR) is a chronic upper respiratory tract disease that inflames the mucous membranes of the nose and occurs when circulating inflammatory cells including eosinophils and basophils migrate...
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Cyst growth, polycystins, and primary cilia in autosomal dominant polycystic kidney disease

Lee SH, Somlo S

  • KMID: 2224270
  • Kidney Res Clin Pract.
  • 2014 Jun;33(2):73-78.
The primary cilium of renal epithelia acts as a transducer of extracellular stimuli. Polycystin (PC)1 is the protein encoded by the PKD1 gene that is responsible for the most common...
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