- The Effects of Phenobarbital or Cholic Acid on Hepatic Microsomal Cytochrome P450 and Hydroxylation of 2-AAF in Cholestatic Rats
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Kim BH, Hong YS, Sung NE
- KMID: 1969538
- Ewha Med J.
- 1981 Sep;4(3):83-89.
- doi: 10.12771/emj.1981.4.3.83
In cholestatic rats, effects of phenobarbital or cholic acid on hepatic microsomal cytochrome p-450 and b5 were investigated. The total contents of both cytochrome p-450 and cytochrome b5 were decreased... -
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- Effect of Bile Acids on Biliary Excretion of Cholesterol in Rabbits
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Hong SS, Kim KH, Kim WJ
- KMID: 2439778
- Yonsei Med J.
- 1973 Dec;14(1):109-115.
The effects of cholic acid and eight related cholanic acid analogs on bile flow and biliary excretion of bile salts and cholesterol were studied in rabbits. Bile acids were infused... -
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- Effects of Exogenous Cholic Acid on Total Hepatic Cytochrome P-450 and b5 in the Bile Duct-ligated Rats
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Choi KJ, Hong YS, Sung NE
- KMID: 1969558
- Ewha Med J.
- 1980 Mar;3(1):21-25.
- doi: 10.12771/emj.1980.3.1.21
We have investigated the effect of administation of exogenous cholic acid whether total hepatic cytochrome P-450 and b5 are altered in the bile duct-ligated rats. The effect of administration of exogenous... -
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- The role of G protein in the activation of phospholipase C from bovine brain
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Kim JH, Lee DJ, Byun YJ
- KMID: 2377584
- Yeungnam Univ J Med.
- 1992 Dec;9(2):288-301.
- doi: 10.12701/yujm.1992.9.2.288
The objective of the present study was to identify the characteristics of phospholipase C (PLC) isozymes purified from bovine brain and to investigate their interrelationship with G protein. The purified PLC... -
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- A Case of Cerebrotendinous Xanthomatosis
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Park CI, Kim YC, Shin JC, Kim YW, Lim KB
- KMID: 2323089
- J Korean Acad Rehabil Med.
- 1998 Apr;22(2):460-464.
Cerebrotendinous Xanthomatosis is a rare inherited autosomal recessive disorder characterized by an increased plasma cholestanol level and the accumulation of sterol in tendon and nervous system. The primary biochemical abnormality... -
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- Bile acid modulation of gastroinstinal smooth muscle contraction and ionic currents
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Lee HK, Lee KH
- KMID: 1917027
- Korean J Physiol Pharmacol.
- 2000 Aug;4(4):333-338.
We have examined whether bile acids can affect the electrical and mechanical activities of circular smooth muscle of canine colon and ileum, using isometric tension measurement or patch clamp technique. It was found... -
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- Electron Misoscopic Morphology of the Gallbladder and Gallstone Formation induced by High Cholesterol-Cholic Acid Diet in Mice
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Han NI, Choi SW, Lee YS, Lee CD, Chung KW, Sun HS
- KMID: 1537985
- Korean J Hepatol.
- 2000 Sep;6(3):360-369.
BACKGROUND/AIMS: The experimental production of cholesterol gallstone suggests that alteration of the nature of gallbladder mucus may be a factor in the induction of gallbladder stones. This study was designed... -
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- Qualitative Alteration in Hepatic Microsomal Cytochrome P-450 Apoproteins Associated with Bile Duct Ligation, and the Administration of Cholic Acid and Phenobarbital
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Sung NE, Kim BH, Hong YS, Choi KJ
- KMID: 2134970
- Ewha Med J.
- 1980 Dec;3(4):157-162.
- doi: 10.12771/emj.1980.3.4.157
We have investigated in rat liver whether different forms of cytochrome P-450 are alterated in hepatic disorders associated with impaired drug metabolism. Total hepatic cytochrome P-450 is decreased after either... -
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- Effect of Colesterol Rich Diet on The Formation of Cholesterol Gallstones in Hamster
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Min YI, Lee SK, Choi HS, Kim MH, Nam SW, Seo DW, Kim YS, Kim HJ, Myung SJ, Shim KN, Kim JS, Kim GS, Kim SY
- KMID: 2240611
- Korean J Gastroenterol.
- 1998 Jul;32(1):75-86.
BACKGROUND AND AIMS: Syrian hamsters are commonly used as a model for experimental induction of gallstones, In Korea, there has been no report on the animal model of cholesterol gallstone... -
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- Bile Acid Inhibition of N-type Calcium Channel Currents from Sympathetic Ganglion Neurons
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Lee HK, Lee KH, Cho ES
- KMID: 2285436
- Korean J Physiol Pharmacol.
- 2012 Feb;16(1):25-30.
- doi: 10.4196/kjpp.2012.16.1.25
Under some pathological conditions as bile flow obstruction or liver diseases with the enterohepatic circulation being disrupted, regurgitation of bile acids into the systemic circulation occurs and the plasma level... -
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- The Affinity of Calmodulin-Affigel for Inositol Triphosphate Kinase From Bovine Brain
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Lim SW, Kim JH
- KMID: 2377305
- Yeungnam Univ J Med.
- 1990 Jun;7(1):39-50.
- doi: 10.12701/yujm.1990.7.1.39
The one event on signaling mechanism is the cleavage by adenyl cyclase of ATP into second messenger, cyclic AMP. The other transfer system of inositol metabolism, it is widely recognized... -
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- Integrative Omics Reveals Metabolic and Transcriptomic Alteration of Nonalcoholic Fatty Liver Disease in Catalase Knockout Mice
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Na J, Choi SA, Khan A, Huh JY, Piao L, Hwang I, Ha H, Park YH
- KMID: 2442004
- Biomol Ther.
- 2019 Feb;27(2):134-144.
- doi: 10.4062/biomolther.2018.175
The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased with the incidence of obesity; however, the underlying mechanisms are unknown. In this study, high-resolution metabolomics (HRM) along with transcriptomics... -
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- Gastric Stump Cancer
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Oh YS, Kim YS, Sin YM, Lee SH, Moon YC, Choi KH, Chung BC
- KMID: 2372685
- J Korean Gastric Cancer Assoc.
- 2001 Sep;1(3):144-149.
PURPOSE: Gastric stump cancer is defined as a cancer that develops in the stomach after a resection in cases of non-malignant or malignant gastric disease. The interval between the gastrectomy... -
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- Dietary chitosan enhances hepatic CYP7A1 activity and reduces plasma and liver cholesterol concentrations in diet-induced hypercholesterolemia in rats
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Moon MS, Lee MS, Kim CT, Kim Y
- KMID: 2313310
- Nutr Res Pract.
- 2007 Sep;1(3):175-179.
The present study was performed to elucidate the hypocholesterolemic action of chitosan on the diet-induced hypercholesterolemia in rats. Male Sprague-Dawley rats (n=24) were fed with chitosan-free diet (Control), diets containing... -
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- Prognosis of Korean patients with primary biliary cirrhosis
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Song BC
- KMID: 1792588
- Korean J Hepatol.
- 2010 Jun;16(2):109-111.
- doi: 10.3350/kjhep.2010.16.2.109
No abstract available. -
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- Effects of Corn Peptide Consumption on Plasma Lipid Profiles in Cholesterol-Fed Rats
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Moon MS, Lee JH, Lee MS, Kwun IS, Chung YI, Lee DH, Kim Y
- KMID: 2270055
- Korean J Nutr.
- 2006 Dec;39(8):728-732.
In this study, the effects of corn peptide consumption on plasma lipid profiles were investigated in high cholesterol dietfed rats. Male Sprague-Dawley rats (n = 21) were fed with corn... -
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- Effects of 16,16-Dimethyl Prostaglandin E2 and Cholesterol on Biliary Mucous Glycoprotein and Gallstone Formation in Guinea Pigs
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Chang JN, Lee JW, Kim IH, Kim SH, Jang DS, Kwon KS, Choi W, Lee DH, Cho HG, Kim PS, Kim HG, Shin YW, Kim YS
- KMID: 1772570
- Korean J Gastroenterol.
- 1999 Dec;34(6):784-792.
BACKGROUND/AIMS: Prostaglandins is proposed to be responsible for gallstone formation in the animal models by hypersecretion of mucus in the gallbladder. This study was performed to determine the effect of... -
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- Gallstone formation and gallbladder mucosal changes in mice fed a lithogenic diet
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Chang HJ, Suh JI, Kwon SY
- KMID: 646307
- J Korean Med Sci.
- 1999 Jun;14(3):286-292.
- doi: 10.3346/jkms.1999.14.3.286
To investigate the pathologic change of gallbladder mucosa related to gallstone formation, 52 mice were fed a lithogenic diet containing 1% cholesterol and 0.5% cholic acid and we evaluated the... -
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- Effect of Korean Red Ginseng on Vaginal Blood Flow and Structure in Hypercholesterolemic Female Rats
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Lee HS, Lee MN, Hwang IS, Kim SO, Ahn K, Park K
- KMID: 2226646
- Korean J Androl.
- 2005 Dec;23(3):159-164.
PURPOSE: The aims of this study were to investigate the effects of Korean Red Ginseng(KRG) on vaginal blood flow and histological changes in a hypercholesterolemic female rat model. MATERIALS AND METHODS:... -
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- Induction of Hepatic Arylamine N-Methyltransferase by a Taurocholate Load in Rats
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Rhee BW, Kwak CS
- KMID: 2325094
- J Korean Surg Soc.
- 2000 Aug;59(2):141-153.
PURPOSE: The possible mechanisms of increased arylamine N-methyl- transferase (AMT) activity in cholestatic rat livers and serum were studied. METHODS: Rats were divided into eight groups: rats receiving a... -
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