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Vitamin D Supplementation is Beneficial for Children with Autism Spectrum Disorder: A Meta-analysis

Song L, Luo X, Jiang Q, Chen Z, Zhou L, Wang D, Chen A

Objective: We conducted a meta-analysis of randomized controlled trials to explore whether vitamin D supplementation is beneficial for symptom improvement in children with autism spectrum disorder. Methods: We systematically searched the...
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Exosome-mediated lnc-ABCA12-3 promotes proliferation and glycolysis but inhibits apoptosis by regulating the tolllike receptor 4/nuclear factor kappa-B signaling pathway in esophageal squamous cell carcinoma

Ma J, Luo Y, Liu Y, Chen C, Chen A, Liang L, Wang W, Song Y

Esophageal squamous cell carcinoma (ESCC) is a kind of malignant tumor with high incidence and mortality in the digestive system. The aim of this study is to explore the function...
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Impact of Older Age Adiposity on Incident Diabetes: A Community-Based Cohort Study in China

Chen A, Zhou W, Hou J, Nevill A, Ding Y, Wan Y, Jester R, Qin X, Hu Z, Chen R

Background: Obesity classifications vary globally and the impact of older age adiposity on incident diabetes has not been well-studied. Methods: We examined a random sample of 2,809 participants aged ≥60 years...
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The Double-Edged Sword Effects of Career Calling on Occupational Embeddedness: Mediating Roles of WorkeFamily Conflict and Career Adaptability

Yang C, Chen A

Based on the conservation of resource theory, we proposed a two-path model to examine the double-edged sword effects of career calling on occupational embeddedness via work–family conflict (WFC) and career...
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A Novel EYA1 Mutation Causing Alternative RNA Splicing in a Chinese Family With Branchio-Oto Syndrome: Implications for Molecular Diagnosis and Clinical Application

Chen A, Ling J, Peng X, Liu X, Mao S, Chen Y, Qin M, Zhang S, Bai Y, Song J, Feng Z, Ma L, He D, Mei L, He C, Feng Y

Objectives. Branchio-oto syndrome (BOS) primarily manifests as hearing loss, preauricular pits, and branchial defects. EYA1 is the most common pathogenic gene, and splicing mutations account for a substantial proportion of...
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Endovascular Strategies in the Management of Acute Limb Ischemia

Lind B, Morcos O, Ferral H, Chen A, Aquisto T, Lee S, Lee CJ

Acute limb ischemia (ALI) represents one of the most common emergent scenarios encountered by a vascular specialist. Despite expedient revascularization, high rates of limb loss are reported along with high...
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Modalities in managing postherpetic neuralgia

Shrestha M, Chen A

Postherpetic neuralgia (PHN) is the most troublesome side effect of Herpes Zoster (HZ), which mainly affects the elderly and immunocompromised populations. Despite the current advancement of treatments, PHN persists in...
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Medication adherence in inflammatory bowel disease

Chan W, Chen A, Tiao D, Selinger C, Leong R

Inflammatory bowel disease (IBD) is a chronic idiopathic inflammatory condition with intestinal and extraintestinal manifestations. Medications are the cornerstone of treatment of IBD. However, patients often adhere to medication poorly....
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Long Non-Coding RNA NORAD Inhibits Breast Cancer Cell Proliferation and Metastasis by Regulating miR-155-5p/ SOCS1 Axis

Liu W, Zhou X, Li Y, Jiang H, Chen A

Purpose: Non-coding RNA activated by DNA damage (NORAD) has been reported to be a cancer-related long non-coding RNA (lncRNA) implicated in the progression of several cancers; however, its role in...
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Medication non-adherence in inflammatory bowel diseases is associated with disability

Perry J, Chen A, Kariyawasam V, Collins G, Choong C, Teh WL, Mitrev N, Kohler F, Leong RW

BACKGROUND/AIMS: Medication non-adherence is common in inflammatory bowel diseases (IBD). The short-term consequences of non-adherence include increased disease relapse but the long-term impact upon patients in terms of daily functional...
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