- Elevated Serum Levels of Thymus and Activation-Regulated Chemokine and Macrophage-Derived Chemokine and Their Relationships with Eosinophilic Inflammatory Markers in Children with Allergic Diseases
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- KMID: 2299451
- Korean J Asthma Allergy Clin Immunol.
- 2012 Dec;32(4):216-223.
BACKGROUND: Thymus and activation-regulated chemokine (CCL17) and macrophage-derived chemokine (CCL22) are known as important mediators in allergic inflammation. Recently many researchers have focused on these mediators, but the role of... -
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- Therapeutic effects of recombinant Salmonella typhimurium harboring CCL22 miRNA on atopic dermatitis-like skin in mice
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Yoon WS, Lee SS, Chae YS, Park YK
- KMID: 1097263
- Exp Mol Med.
- 2011 Feb;43(2):63-70.
- doi: 10.3858/emm.2011.43.2.008
Th-2-biased immune responses are known to play a key role in the pathogenesis of atopic dermatitis. In particular, the macrophage-derived chemokine CCL22 is directly implicated in Th-2-associated skin inflammatory reactions,... -
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- Mechanism of Macrophage-Derived Chemokine/CCL22 Production by HaCaT Keratinocytes
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Yano C, Saeki H, Komine M, Kagami S, Tsunemi Y, Ohtsuki M, Nakagawa H
- KMID: 2264803
- Ann Dermatol.
- 2015 Apr;27(2):152-156.
- doi: 10.5021/ad.2015.27.2.152
BACKGROUND: CC chemokine ligand 17 (CCL17) and CCL22 are the functional ligands for CCR4. We previously reported that inhibitors of nuclear factor-kappa B and p38 mitogen-activated protein kinase (p38 MAPK),... -
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- Anti-Inflammatory Effect of Quercetagetin, an Active Component of Immature Citrus unshiu, in HaCaT Human Keratinocytes
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Kang GJ, Han SC, Ock JW, Kang HK, Yoo ES
- KMID: 1502516
- Biomol Ther.
- 2013 Mar;21(2):138-145.
Citrus fruit contain various flavonoids that have multiple biological activities. However, the content of these flavonoids are changed during maturation and immature Citrus is known to contain larger amounts than... -
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- Dieckol, a Component of Ecklonia cava, Suppresses the Production of MDC/CCL22 via Down-Regulating STAT1 Pathway in Interferon-gamma Stimulated HaCaT Human Keratinocytes
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Kang NJ, Koo DH, Kang GJ, Han SC, Lee BW, Koh YS, Hyun JW, Lee NH, Ko MH, Kang HK, Yoo ES
- KMID: 2380333
- Biomol Ther.
- 2015 May;23(3):238-244.
- doi: 10.4062/biomolther.2014.141
Macrophage-derived chemokine, C-C motif chemokine 22 (MDC/CCL22), is one of the inflammatory chemokines that controls the movement of monocytes, monocyte-derived dendritic cells, and natural killer cells. Serum and skin MDC/CCL22... -
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- Serum Levels of Type 2 Chemokines in Lepromatous Leprosy Patients
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Lew W, Nakamura K, Tada Y, Kwahck H, Chang SK, Tamaki K
- KMID: 1974521
- Immune Netw.
- 2002 Dec;2(4):223-226.
- doi: 10.4110/in.2002.2.4.223
BACKGROUND: The type 2 deviated immunological state is predominant in lepromatous leprosy. Erythema nodosum leprosum (ENL) is an immune-complex mediated reaction that typically occurs in lepromatous leprosy. To date, the... -
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- Increased Expression and Role of Thymic Stromal Lymphopoietin in Nasal Polyposis
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Kimura S, Pawankar R, Mori S, Nonaka M, Masuno S, Yagi T, Okubo K
- KMID: 1803324
- Allergy Asthma Immunol Res.
- 2011 Jul;3(3):186-193.
- doi: 10.4168/aair.2011.3.3.186
PURPOSE: Nasal polyposis is a chronic inflammatory disease of the upper airways often associated with asthma and characterized by markedly increased numbers of eosinophils, Th2 type lymphocytes, fibroblasts, goblet cells... -
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- Decreased Expression of FOXP3 in Nasal Polyposis
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Roongrotwattanasiri K, Pawankar R, Kimura S, Mori S, Nonaka M, Yagi T
- KMID: 2130375
- Allergy Asthma Immunol Res.
- 2012 Jan;4(1):24-30.
- doi: 10.4168/aair.2012.4.1.24
PURPOSE: The pathogenesis of nasal polyposis (NP) is unclear. Eosinophils and mast cells are considered to play important roles in this process. In addition, the levels of Th2-type cells are... -
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- The Chloroform Fraction of Carpinus tschonoskii Leaves Inhibits the Production of Inflammatory Mediators in HaCaT Keratinocytes and RAW264.7 Macrophages
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Kang GJ, Kang NJ, Han SC, Koo DH, Kang HK, Yoo BS, Yoo ES
- KMID: 1432309
- Toxicol Res.
- 2012 Dec;28(4):255-262.
Inflammation is the immune system's response to infection and injury-related disorders, and is related to pro-inflammatory factors (NO, PGE2, cytokines, etc.) produced by inflammatory cells. Atopic dermatitis (AD) is a... -
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