- Mucosal Restitution
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Yoon BC
- KMID: 772966
- Korean J Gastroenterol.
- 2006 Jun;47(6):409-412.
The repair of superficially damaged intestinal epithelium is initiated by restitution. Restitution is the covering of damaged area by the movement of neighboring epithelial cells without cell proliferation. Phenotypic switching... -
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- Fibroblasts in three dimensional matrices: cell migration and matrix remodeling
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Rhee S
- KMID: 1099862
- Exp Mol Med.
- 2009 Dec;41(12):858-865.
- doi: 10.3858/emm.2009.41.12.096
Fibroblast-collagen matrix culture has facilitated the analysis of cell physiology under conditions that more closely resemble an in vivo-like environment compared to conventional 2-dimensional (2D) cell culture. Furthermore, it has... -
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- ICAM-1/LFA-1 interaction contributes to the induction of endothelial cell-cell separation: implication for enhanced leukocyte diapedesis
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Wee H, Oh HM, Jo JH, Jun CD
- KMID: 1123808
- Exp Mol Med.
- 2009 May;41(5):341-348.
- doi: 10.3858/emm.2009.41.5.038
The basic route and mechanism for diapedesis has not yet to be fully defined. Here we present evidence that "cell-cell separation" between endothelial cells (ECs) may provide a route for... -
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- Neutrophil Extravasation Cascade: What Can We Learn from Two-photon Intravital Imaging?
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Park SA, Hyun YM
- KMID: 2362795
- Immune Netw.
- 2016 Dec;16(6):317-321.
- doi: 10.4110/in.2016.16.6.317
Immune cells (leukocytes or white blood cells) move actively and sensitively based on body conditions. Despite their important role as protectors inside the body, it is difficult to directly observe... -
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- Tie2 is tied at the cell-cell contacts and to extracellular matrix by Angiopoietin-1
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Fukuhara S, Sako K, Noda K, Nagao K, Miura K, Mochizuki
- KMID: 1123460
- Exp Mol Med.
- 2009 Mar;41(3):133-139.
- doi: 10.3858/emm.2009.41.3.016
Angiopoietin-1 (Ang1) binds to and activates Tie2 receptor tyrosine kinase. Ang1-Tie2 signal has been proposed to exhibit two opposite roles in the controlling blood vessels. One is vascular stabilization and... -
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- The adaptor protein LAD/TSAd mediates laminin-dependent T cell migration via association with the 67 kDa laminin binding protein
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Park E, Choi Y, Ahn E, Park I, Yun Y
- KMID: 1009394
- Exp Mol Med.
- 2009 Oct;41(10):728-736.
- doi: 10.3858/emm.2009.41.10.079
The adaptor protein, LAD/TSAd, plays essential roles in T cell activation. To further understand the functions of this protein, we performed yeast two-hybrid screening using TSAd as bait and identified... -
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- The role of the alpha4 integrin-paxillin interaction in regulating leukocyte trafficking
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Rose DM
- KMID: 1094143
- Exp Mol Med.
- 2006 Jun;38(3):191-195.
The movement of leukocytes from the blood into peripheral tissues is a central feature of immune surveillance, but also contributes to the pathogenesis of inflammatory and autoimmune diseases. Integrins are... -
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- The role of Rho GTPases in the regulation of the rearrangement of actin cytoskeleton and cell movement
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Begum R, Nur-E-Kamal MSA, Zaman MA
- KMID: 1094080
- Exp Mol Med.
- 2004 Aug;36(4):358-366.
The rearrangement of the actin cytoskeleton has been shown to play a critical role in the development of transformation and malignant phenotype of cancer cells. Rho family GTPases regulate the... -
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- Mechanism of Neuronal Migration in Human Foetal Cerebrum In-vitro
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Choi BH
- KMID: 687776
- Yonsei Med J.
- 1979 Dec;20(2):92-104.
- doi: 10.3349/ymj.1979.20.2.92
Active migration of immature neurons occurs when fragments of human foetal cerebral tissues are explanted as organotypic cultures. The sequence of events during neuronal migration is orderly and consistent under... -
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- In vitro migration capacity of human adipose tissue-derived mesenchymal stem cells reflects their expression of receptors for chemokines and growth factors
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Baek SJ, Kang SK, Ra JC
- KMID: 1123372
- Exp Mol Med.
- 2011 Oct;43(10):596-603.
- doi: 10.3858/emm.2011.43.10.069
The homing properties of adipose tissue-derived mesenchymal stem cells (AdMSCs) have stimulated intravenous applications for their use in stem cell therapy. However, the soluble factors and corresponding cellular receptors responsible... -
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- Enhancement of Cell Migration by Corticotropin-Releasing Hormone (CRH) in Human Gastric Cancer Cell Line, MKN-28
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Cheon S, Cho D
- KMID: 1515492
- Immune Netw.
- 2004 Dec;4(4):244-249.
- doi: 10.4110/in.2004.4.4.244
BACKGROUND: Corticotropin-Releasing Hormone (CRH), an important regulator of stress response, has a potent immunoregulatory effect with the ability to promote the growth of various cancer through CRH receptor type 1... -
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- RASSF1A Suppresses Cell Migration through Inactivation of HDAC6 and Increase of Acetylated alpha-Tubulin
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Jung HY, Jung JS, Whang YM, Kim YH
- KMID: 2167619
- Cancer Res Treat.
- 2013 Jun;45(2):134-144.
PURPOSE: The RAS association domain family protein 1 (RASSF1) has been implicated in a tumor-suppressive function through the induction of acetylated alpha-tubulin and modulation of cell migration. However, the mechanisms... -
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- Cell Death and Cell Proliferation during Histogenesis in the Rat Retina after Birth
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Oh SJ, Lee YS, Lee MY, Chun MH
- KMID: 2224612
- Korean J Anat.
- 1997 Dec;30(6):725-740.
During development of central nervous system, cell proliferation, cell migration, cell differentiation and cell death are required. It has been reported that a number of cells are dying during development... -
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- Role of Apoptosis in Development of Experimental Rat Cerebral Cortical Dysplasia
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Lee YJ, Chung CK
- KMID: 2181951
- J Korean Epilepsy Soc.
- 2003 Dec;7(2):101-107.
Microgyria is one type of cortical dysplasia with dyslaminations and anomalous cell densities, which could be produced experimentally. In a normal rat cortical development, overproduced neuroblasts gradually die by apoptosis.... -
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- Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells
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Lee EJ, Choi EM, Kim SR, Park JH, Kim H, Ha KS, Kim YM, Kim SS, Choe M, Kim JI, Han JA
- KMID: 756069
- Exp Mol Med.
- 2007 Aug;39(4):469-476.
Osteosarcoma is the most common primary bone tumor, but the pathogenesis is not well understood. While cyclooxygeanse-2 (COX-2) is known to be closely associated with tumor growth and metastasis in... -
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- Recombinant tetra-cell adhesion motifs supports adhesion, migration and proliferation of keratinocytes/fibroblasts, and promotes wound healing
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Jung MY, Thapa N, Kim JE, Yang JD, Cho BC, Kim IS
- KMID: 1090969
- Exp Mol Med.
- 2007 Oct;39(5):663-672.
An extracellular matrix protein plays an important role in skin wound healing. In the present study, we engineered a recombinant protein encompassing the 9th and 10th type III domains of... -
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- Effect of BMI1 Knockdown on Cell Proliferation, Apoptosis, Invasiveness, and Migration of U251 Glioma Cells
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Kim DJ, Jun YH, Kim DH, Kim JJ
- KMID: 2283755
- Korean J Phys Anthropol.
- 2015 Jun;28(2):69-78.
- doi: 10.11637/kjpa.2015.28.2.69
BMI1 belongs to the polycomb-repressive complex 1 (PRC1) family of genes that are conserved chromatin silencers. These are essential for maintaining both the normal and cancerous stem cell state. In... -
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- Inhibitory effect of capsaicin on B16-F10 melanoma cell migration via the phosphatidylinositol 3-kinase/Akt/Rac1 signal pathway
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Shin DH, Kim OH, Jun HS, Kang MK
- KMID: 1104802
- Exp Mol Med.
- 2008 Oct;40(5):486-494.
- doi: 10.3858/emm.2008.40.5.486
Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide), the major pungent ingredient of red pepper, has been reported to possess anti-carcinogenic and anti-mutagenic activities. In this study, the anti-migration activity of capsaicin on highly metastatic B16-F10... -
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- Lysophosphatidic acid induces cell migration through the selective activation of Akt1
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Kim EK, Yun SJ, Do KH, Kim MS, Cho M, Suh DS, Kim CD, Kim JH, Birnbaum M, Bae SS
- KMID: 1094124
- Exp Mol Med.
- 2008 Aug;40(4):445-452.
- doi: 10.3858/emm.2008.40.4.445
Akt plays pivotal roles in many physiological responses including growth, proliferation, survival, metabolism, and migration. In the current studies, we have evaluated the isoform-specific role of akt in lysophosphatidic acid... -
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- Presence of E-Cadherin and its Messenger Ribonucleic Acid in Leiomyoma and Myometrium
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Lee KH, Kang KC
- KMID: 2261105
- Korean J Obstet Gynecol.
- 1998 Aug;41(8):2084-2088.
Cell adhesion molecules (CAMs) may be categorized into cadherins, integrins, the immunoglobulin superfamily and others. E-cadherin, a calcium-dependent cell adhesion molecule, is a 120 kDa transmembrane glycoprotein that is localized... -
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