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Study on the Expression of mRNA of Tumor Necrosis Factor-alpha and Interleukin-6 in the Cell Lines of Squamous Cell Carcinoma

Ahn JS, Kim KW, Lee JH

  • KMID: 1961187
  • J Korean Assoc Oral Maxillofac Surg.
  • 2001 Dec;27(6):535-542.
The purpose of this study was to examine the mRNA levels of TNF-alpha and IL-6 in the cell lines of normal oral keratocyte and oral squamous cell carcinoma. Total RNA...
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Effect of Retrovirus Mediated TNF-α Gene Transfer to Tumor Necrosis Factor(TNF) Sensitive Tumor Cell Lines on Sensitivity to TNF

Oh YM, Park KY, Jung MP, Yoo CG, Kim YW, Han SG, Sim YS, Han YC

BACKGROUND: Since tumor necrosis factor was discovered in 1975, TNF has been well known about its cytotoxic effect on tumor cells in vivo and in vitro. According to the recent...
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Cancer Cell Line Panels Empower Genomics-Based Discovery of Precision Cancer Medicine

Kim HS, Sung YJ, Paik S

Since the first human cancer cell line, HeLa, was established in the early 1950s, there has been a steady increase in the number and tumor type of available cancer cell...
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COX-2 inhibitor induced apoptosis in oral squamous cell carcinoma cell line through AKT pathway

Seo YH, Han SJ, Lee JH

  • KMID: 2184413
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2008 Jan;30(1):30-40.
The objectives of this study was to check up the effect of celecoxib, COX-2 inhibitor, on the pathogenesis of oral squamous cell carcinoma. After mefenamic acid, aspirin and celecoxib, COX-2...
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Histologic Similarity between the Primary Tumor and Xenograft of AMC-HN Cell Lines in Nude Mice

Jun HK, Kim SY, Gong GY

  • KMID: 2274358
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Nov;40(11):1546-1553.
BACKGROUND: Head and neck cancer(HNC) is the sixth most common cancer worldwide. Squamous cell carcinoma(SCC) accounts for 85-90% of all HNC. However, its biologic behavior has little been known yet. OBJECTIVES:...
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Effect of TNF-alpha Gene Transfer to Respiratory Cancer Cell Lines onSensitivity to Anticancer drugs

Mo EK, Lee JH, Lee KY, Yoo CG, Kim YW, Han SK, Shim YS, Choi HS

  • KMID: 2317910
  • Tuberc Respir Dis.
  • 1995 Jun;42(3):302-313.
BACKGROUND: Tumor necrosis factor(TNF) showed antitumor cytolytic effects on sensitive tumor cells in numerous in vivo and in vitro studies. But it could not be administered systemically to human because...
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Chemotherapeutic Candidate Inducing Immunological Death of Human Tumor Cell Lines

Oh SJ, Ryu CK, Choi I, Baek SY, Lee H

The immunological death induction by EY-6 on the human tumor cell lines was screened. Human colon carcinoma (HCT15, HCT116), gastric carcinoma (MKN74, SNU668), and myeloma (KMS20, KMS26, KMS34) cells were...
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Immunologic effects of recombinant gamma-interferon on human gastrointestinal tumor cell lines

Chung DH, Bae YM, Park JG, Park SH, Kim YI, Lee SK

  • KMID: 1694058
  • J Korean Cancer Assoc.
  • 1991 Mar;23(1):10-19.
No abstract available.
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Expression of Cell Cycle Regulatory Proteins on the Solid Tumor Cell Line After Irradiation Under Hypoxia

Park KA, Choi YJ, Choi EJ, Hwang HJ, Lee YW, Lee WT, Lee JE

  • KMID: 2224493
  • Korean J Anat.
  • 2005 Dec;38(6):567-578.
Human solid tumors are less well oxygenated than normal tissues. This leads to resistance to radiotherapy and anticancer chemotherapy. Many of genes encoding proteins induced by hypoxia are potential products...
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Establishment of a canine mammary gland tumor cell line and characterization of its miRNA expression

Osaki T, Sunden Y, Sugiyama A, Azuma K, Murahata Y, Tsuka T, Ito N, Imagawa T, Okamoto Y

Canine mammary gland tumors (CMGTs), which are the most common neoplasms in sexually intact female dogs, have been suggested as a model for studying human breast cancer because of several...
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Effects of Interleukin-2 Transduction into the Human Hepatoma Cell Lines Using Retroviral Vector

Gong SJ, Yoo NC, Kim JH, Shin DH, Uhm HD, Jeong SJ, Cho JY, Rha SY, Kim YS, Chung HC, Roh JK, Min JS, Kim BS

  • KMID: 2059119
  • J Korean Cancer Assoc.
  • 1997 Aug;29(4):555-564.
PURPOSE: We compared the differences between parent hepatoma cell lines and interleukin-2 (IL-2) transduced hepatoma cell lines using N2A/IL-2 and LNC/IL-2 retrovirus with regards to in vitro sensitivity to peripheral...
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Immunologic Response to Cryoablation of Squamous Cell Carcinoma

Yoo CK, Chang C, Choi JY, Hong JH, Kim HJ, Cho S, Jung KY, Kwon SY

  • KMID: 2276830
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Jan;51(1):64-69.
BACKGROUND AND OBJECTIVES: Cryoablation has been recognized as a potential tool in the treatment of cancer. Beside its ability to cause local destruction of the primary tumor, cryoablation has been...
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Species specificity of a novel factor which augments the expression of MHC class I antigens on tumor cell lines

Puri N, Raval A, Saxena RK

  • KMID: 2045609
  • Exp Mol Med.
  • 1997 Jun;29(2):129-132.
A novel factor which augments the expression of major histocompatibility complex I (MHC augmenting factor or MHC-AF) antigens on tumor cell lines, has been isolated from the culture supernatants of...
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Interleukin-4 Receptor Expression on Human Renal Cell Carcinoma Cell Lines by a Reverse Transcription-Polymerase Chain Reaction

Cheon J, Chung DJ, Choi JB, Koh SK, Sohn JW

  • KMID: 1913970
  • Korean J Urol.
  • 1995 Feb;36(2):121-127.
Recently interleukin-4 (IL-4) has been suggested to be a promising therapeutic agent for the malignant tumors of both murine and human origin. The effect of IL-4 is mediated by IL-4...
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The Effect of HIF-1alpha siRNA on Growth and Chemosensitivity of Mia-paca Cell Line

Yang L, Kang WK

PURPOSE: Hypoxia-inducible factor-1alpha (HIF-1alpha) primarily mediates the hypoxic response. HIF-1alpha induction by various stimuli contributes to cell proliferation and survival. To investigate the effect of HIF-1alpha, we used small interfering...
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The Effect of Irradiation and Epidermal Growth Factor on Cell Cycle and Apoptosis Induction in Human Epithelial Tumor Cell Lines

Han WJ, Heo MS, Lee SS, Choi SC, Park TW

  • KMID: 2074866
  • Korean J Oral Maxillofac Radiol.
  • 2000 Mar;30(1):71-79.
PURPOSE: This study was aimed to evaluate the cell cycle arrest and apoptosis induction after irradiation and epidermal growth factor(EGF) treatment in three human epithelial tumor cell lines(A431, Siha, KB). MATERIALS...
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p41-Arc, a regulatory subunit of Arp2/3 complex, can induce premature senescence in the absence of p53 and Rb

Yun UJ, Park SE, Shin DY

Cellular senescence is a tumor-suppressive process instigated by proliferation in the absence of telomere replication, by cellular stresses such as oncogene activation, or by activation of the tumor suppressor proteins,...
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Differential Thioredoxin Reductase Activity from Human Normal Hepatic and Hepatoma Cell Lines

Jung HI, Lim HW, Kim BC, Park EH, Lim CJ

  • KMID: 2428322
  • Yonsei Med J.
  • 2004 Apr;45(2):263-272.
Thioredoxin reductase (TrxR), a component of the thioredoxin system, including thioredoxin (Trx) and NADPH, catalyzes the transfer of electrons from NADPH to Trx, acts as a reductant of disulfide-containing proteins...
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Antitumor activity of adriamycin and the analogue, THP-adriamycin and epirubicin, against human tumor cell lines

Hong WS, Kim CM, Lee MS, Kang YK, Lee CT, Kim YC, Lee JO, Kang TW

  • KMID: 1742125
  • J Korean Cancer Assoc.
  • 1991 Jun;23(2):259-265.
No abstract available.
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Chromosomal Aberrations in Ovarian Carcinoma Cell Line, SNU - S , Using Chromosome Painting

Kang JS, Kim DW, Chun YH, Park SH

  • KMID: 2137119
  • J Korean Cancer Assoc.
  • 2000 Feb;32(1):120-128.
PURPOSE: The characterization of all recognizable chromosomal rearrangements was dis- turbed by technical limitation of conventional cytogenetic methods. Recently, the strong usefullness of generation of chromosome specific painting probes in identification of marker...
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