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10 results

Correlative Effect between in vivo Hollow Fiber Assay and Xenografts Assay in Drug Screening

Lee KH, Rhee KH

  • Cancer Res Treat.
  • 2005 Jun;37(3):196-200.
PURPOSE: This study was carried out to assess the usage of an in vivo hollow fiber assay to screen drugs with highly predictive accuracy. MATERIALS AND METHODS: The assay systems...
Enhancement of Radiation Effects by Flavopiridol in Uterine Cervix Cancer Cells

Kim S, Wu HG, Shin JH, Park HJ, Kim IA, Kim IH

  • Cancer Res Treat.
  • 2005 Jun;37(3):191-195.
PURPOSE: To determine the effects of combinations of radiation and flavopiridol, an inhibitor of cyclin-dependent kinases and global transcription, in a human uterine cervix cancer cell line. MATERIALS AND METHODS:...
Synergistic Effect of Ionizing Radiation and beta-lapachone against RKO Human Colon Adenocarcinoma Cells

Kim EJ, Ji IM, Ahn KJ, Choi EK, Park HJ, Lim BU, Song CW, Park HJ

  • Cancer Res Treat.
  • 2005 Jun;37(3):183-190.
PURPOSE: To reveal the interaction between beta-Lapachone (beta-lap) and ionizing radiation in causing cell death in RKO human colon adenocarcinoma cells, and to elucidate the potential usefulness of combined beta-lap...
Intensity of Tumor Budding as an Index for the Malignant Potential in Invasive Rectal Carcinoma

Ha SS, Choi HJ, Park KJ, Kim JM, Kim SH, Roh YH, Kwon HC, Roh MS

  • Cancer Res Treat.
  • 2005 Jun;37(3):177-182.
PURPOSE: The aim of this study was to quantitatively assess the intensity of tumor budding in rectal carcinoma and to determine how it correlates with the malignant potential. MATERIALS AND...
Co-Expression of Cox-2, C-Met and beta-catenin in Cells Forming Invasive front of Gallbladder Cancer

Moon WS, Park HS, Lee H, Pai R, Tarnawski , Kim KR, Jang KY

  • Cancer Res Treat.
  • 2005 Jun;37(3):171-176.
PURPOSE: Gallbladder cancer is a malignancy with poor prognosis, predominantly resulting from invasion and metastasis. Our previous studies have demonstrated that prostaglandin E2 (PGE2), generated by cyclooxygenase 2 (Cox-2), transactivates...
Expression of Cyclooxygenase-2 in Human Breast Cancer: Relationship with HER-2/neu and other Clinicopathological Prognostic Factors

Nam E, Lee SN, Im SA, Kim DY, Lee KE, Sung SH

  • Cancer Res Treat.
  • 2005 Jun;37(3):165-170.
PURPOSE: Previous epidemiologic studies have demonstrated that nonsteroidal anti-inflammatory drugs can reduce the risk of breast cancer, and this possibly happens via cyclooxygenase (COX) inhibition. Moreover, growth factor-inducible COX-2, which...
Assessment of Tumor Regression by Consecutive Pelvic Magnetic Resonance Imaging and Dose Modification during High- Dose-Rate Brachytherapy for Carcinoma of the Uterine Cervix

Nam TK, Nah BS, Choi HS, Chung WK, Ahn SJ, Kim SM, Song JY, Yoon MS

  • Cancer Res Treat.
  • 2005 Jun;37(3):157-164.
PURPOSE: To assess tumor regression, as determined by pelvic magnetic resonance imaging (MRI), and evaluate the efficacies and toxicities of the interim brachytherapy (BT) modification method, according to tumor regression...
Multidimensional Constructs of the EORTC Quality of Life Questionnaire (QLQ-C30) in Korean Cancer Patients with Heterogeneous Diagnoses

Lee EH, Chun M, Wang HJ, Lim HY, Choi JH

  • Cancer Res Treat.
  • 2005 Jun;37(3):148-156.
PURPOSE: The aim of this study was to evaluate the multidimensional constructs of the EORTC Quality of Life Questionnaire (QLQ-C30) in patients with cancer, employing not only the commonly used...
The Surgeon's Expertise-Outcome Relationship in Gastric Cancer Surgery

Yu W, Yun YK, Whang I, Choi GS

  • Cancer Res Treat.
  • 2005 Jun;37(3):143-147.
PURPOSE: The surgical caseload or duration of practice of a surgeon may influence the outcomes of gastric cancer surgery. This study aimed to clarify the surgical quality provided by specialized...
High-Dose Chemotherapy of Cyclophosphamide, Thiotepa and Carboplatin (CTCb) followed by Autologous Stem-Cell Transplantation as a Consolidation for Breast Cancer Patients with 10 or more Positive Lymph Nodes: a 5-Year follow-Up Results

Sohn HJ, Kim SH, Lee GW, Kim S, Ahn JH, Kim SB, Kim SW, Kim WK, Suh C

  • Cancer Res Treat.
  • 2005 Jun;37(3):137-142.
PURPOSE: The benefit of consolidation high-dose chemotherapy (HDC) for high-risk primary breast cancer is controversial. We evaluated the efficacy and safety of consolidation HDC with cyclophosphamide, thiotepa and carboplatin (CTCb)...

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