- Increased Neurofilament Light Chain Is Associated with Increased Risk of Long-Term Mortality in Cerebral Small Vessel Disease
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Jacob MA, Peters N, Cai M, Duering M, Engelter ST, Kuhle J, de Leeuw FE, Tuladhar AM
- KMID: 2530533
- J Stroke.
- 2022 May;24(2):296-299.
- doi: 10.5853/jos.2021.04385
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- Spinosin Attenuates Alzheimer’s Disease-Associated Synaptic Dysfunction via Regulation of Plasmin Activity
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Cai M, Jung I, Kwon H, Cho E, Jeon J, Yun J, Lee YC, Kim DH, Ryu JH
- KMID: 2507841
- Biomol Ther.
- 2020 Mar;28(2):131-136.
- doi: 10.4062/biomolther.2019.076
Hippocampal synaptic dysfunction is a hallmark of Alzheimer’s disease (AD). Many agents regulating hippocampal synaptic plasticity show an ameliorative effect on AD pathology, making them potential candidates for AD therapy.... -
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- First Report of Green Mold Disease Caused by Trichoderma hengshanicum on Ganoderma lingzhi
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Cai M, Idrees M, Zhou Y, Zhang C, Xu J
- KMID: 2509092
- Mycobiology.
- 2020 Oct;48(5):427-430.
- doi: 10.1080/12298093.2020.1794230
Ganoderma lingzhi is a well-known source of natural fungal medicines which has been given for the treatment of several diseases. China is one of the major commercial producers of Ganoderma... -
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- Molecular factors related to skeletal muscle atrophy in a mouse model of amyotrophic lateral sclerosis
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Cai M, Yang EJ
- KMID: 2510279
- J Biomed Transl Res.
- 2020 Dec;21(4):143-151.
- doi: 10.12729/jbtr.2020.21.4.143
Amyotrophic lateral sclerosis (ALS) is progressive neurological disease that results in the death of motor neurons in the brain and spinal cord, leading to a decrease in skeletal muscle size... -
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- Electroacupuncture ameliorates blood-brain barrier dysfunction in 5XFAD Alzheimer’s animal model
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Cai M, Lee JH, Yang EJ
- KMID: 2528068
- J Biomed Transl Res.
- 2021 Sep;22(3):121-133.
- doi: 10.12729/jbtr.2021.22.3.121
Alzheimer’s disease (AD) is an irreversible and progressive neurodegenerative disease accompanied by aging, followed by memory impairment and cognitive decline. Although numerous attempts have been made to develop treatments for... -
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- A Large-Scale, Stratified Genetic Analysis of the Major Histocompatibility Complex Region in Early- and LateOnset Psoriasis in China
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Zhou Y, Cai M, Sheng Y, Zhang X
- KMID: 2510157
- Ann Dermatol.
- 2021 Feb;33(1):61-67.
- doi: 10.5021/ad.2021.33.1.61
Background: Psoriasis vulgaris is a chronic inflammatory skin disease which occur at any age. It can be clinically classified into two age-onset subtypes: early-onset psoriasis (EOP;＜40 years) and late-onset psoriasis... -
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- Exploration and Validation of the Performance of Hemoglobin A1c in Detecting Diabetes in CommunityDwellers With Hypertension
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Qiu S, Du Z, Li W, Chen J, Wu H, Liu J, Cai M, Wang B, Guo H, Sun Z
- KMID: 2507791
- Ann Lab Med.
- 2020 Nov;40(6):457-465.
- doi: 10.3343/alm.2020.40.6.457
Background: Diabetes can complicate hypertension management by increasing the risk of cardiovascular disease (CVD) and all-cause mortality. Studies targeting diabetes detection in hypertensive individuals demonstrating an increased risk of diabetes... -
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- The Efficacy and Underlying Mechanism of Moxibustion in Preventing Cognitive Impairment: A Systematic Review of Animal Studies
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Choe S, Cai M, Jerng UM, Lee JH
- KMID: 2405304
- Exp Neurobiol.
- 2018 Feb;27(1):1-15.
- doi: 10.5607/en.2018.27.1.1
Cognitive impairment is age-related and manageable only with early diagnosis and prevention. Moxibustion is widely accepted in East Asia as useful for preventing cognitive impairment. This systematic review of animal... -
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- Theracurmin Ameliorates Cognitive Dysfunctions in 5XFAD Mice by Improving Synaptic Function and Mitigating Oxidative Stress
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Kim J, Kim J, Huang Z, Goo N, Bae HJ, Jeong Y, Park HJ, Cai M, Cho K, Jung SY, Bae SK, Ryu JH
- KMID: 2447860
- Biomol Ther.
- 2019 May;27(3):327-335.
- doi: 10.4062/biomolther.2019.046
As the elderly population is increasing, Alzheimer's disease (AD) has become a global issue and many clinical trials have been conducted to evaluate treatments for AD. As these clinical trials... -
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