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A case of Rubinstein-Taybi Syndrome with a CREBbinding protein gene mutation

Kim SH, Lim BC, Chae JH, Kim KJ, Hwang YS

Rubinstein-Taybi syndrome (RTS) is a congenital disorder characterized by typical facial features, broad thumbs and toes, with mental retardation. Additionally, tumors, keloids and various congenital anomalies including congenital heart defects...
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Immunohistochemical Expression of p53 Protein and CREB-binding Protein in Polyps and Adenocarcinomas of Colon

Pak JS, Park YG, Kim MK

  • KMID: 2325069
  • J Korean Surg Soc.
  • 2005 Jul;69(1):48-53.
Purpose: Alterations in the structure of the p53 protein are one of the most common changes associated with human cancers. The CREB-binding protein(CBP) is a transcriptional co-activators of various sequence-specific...
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Immunohistochemical Expression of p53 Protein and CREB-binding Protein in Gastric Adenocarcinomas

Noh TH, Chi KC, Lim HM, Lee JH, Park YG, Kim BG, Kim MK, Kim JS

  • KMID: 2040614
  • J Korean Surg Soc.
  • 2007 Jun;72(6):467-472.
PURPOSE: The wild-type p53 protein participates in suppressing cell transformations while its mutant forms has tumorigenic potential. Alterations in the structure of the p53 protein are one of the most...
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Butyrate regulates leptin expression through different signaling pathways in adipocytes

Soliman MM, Ahmed MM, Salah-eldin AE, Abdel-Aal

Leptin is an adipocytokine that regulates body weight, and maintains energy homeostasis by promoting reduced food intake and increasing energy expenditure. Leptin expression and secretion is regulated by various factors...
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