- Expression of Survivin, HSP90, Bcl-2 and Bax Proteins in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced Rat Bladder Carcinogenesis
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Lee SD, Park SW, Hong SA, Kwon GY, Lee TJ
- KMID: 1640303
- Korean J Pathol.
- 2006 Oct;40(5):333-338.
BACKGROUND: Survivin belongs to the inhibitor of apoptosis family, and it has recently been found to be expressed in most solid tumors. Therefore, its expression is suggested to have prognostic... -
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- The Effect of Cyclooxygenase-2 Inhibitor on the Gene Expression Profile of N-butyl-N-(4-hydroxybutyl) nitrosamine-induced Rat Urinary Bladder Cancer
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Kwon SM, Oh HY, Lee EJ, Kim SI, Hong SJ
- KMID: 2294180
- Korean J Urol.
- 2006 Mar;47(3):310-315.
- doi: 10.4111/kju.2006.47.3.310
PURPOSE: Cyclooxygenase (COX)-2 plays an important role in promoting cancer cell proliferation and angiogenesis in human bladder cancer. In this study, we investigated the antitumor or antiangiogenic effects of selective... -
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- Scanning electron microscopic findings in changes of bladder epithelium induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in rat
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Yoon JY, Han CH, Cho YH, Heang TG, Yoon MS, Park YH, Lee MC
- KMID: 2060389
- Korean J Urol.
- 1992 Aug;33(4):583-587.
N-buty1-N-(4-hydroxybutyl)nitrosamine(BBN) is known to have a strong. specific carcinogenic action on the urinary bladder of rats. Rat bladder lesions induced by BBN are very similar to those of Pusan histopathologically.... -
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- Cyclooxygenase-2 Inhibitor Delayed the Tumorigenesis of N-Butyl-N-(4-hydroxybutyl)nitrosamine-induced Rat Urinary Bladder Cancer Model
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Kwon SM, Oh HY, Kim SI, Hong SJ
- KMID: 2293276
- Korean J Urol.
- 2004 Jun;45(6):578-584.
PURPOSE: Cyclooxygenase-2 (COX-2) plays an important role in promoting cancer cell proliferation and angiogenesis in human bladder cancer. The selective COX-2 inhibitor has antitumor activities in vivo and in vitro... -
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- The significance of nucleolar organizer regions in bladder epithelial lesions induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in rat
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Park KJ, Yoon JY
- KMID: 2036820
- Korean J Urol.
- 1992 Apr;33(2):177-183.
It is known that the activity of tumor cells correlates with the malignant potential of tumors. Nucleolar organizer regions(NORs) are loops of DNA which occur in nucleoli and which possess... -
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