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Comparative Analysis of Dibutyric cAMP and Butyric Acid on the Differentiation of Human Eosinophilic Leukemia EoL-1 Cells

Jung Y

Purification of enough numbers of circulating eosinophils is difficult because eosinophils account for less than 5% peripheral blood leukocytes. Human eosinophilic leukemia EoL-1 cells have been considered an in vitro...
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Regulation of fibronectin gene expression by cyclic AMP and phorbol myristate acetate in HT-1080 human fibrosarcoma cells

Lee BH, Park RW, Kim IS

  • KMID: 755015
  • Exp Mol Med.
  • 1998 Dec;30(4):240-245.
We studied the regulation of fibronectin (FN) gene expression by cAMP and phorbol-12-myristate-13-acetate (PMA) in HT-1080 human fibrosarcoma cells. Dibutyryl cAMP increased FN synthesis and mRNA levels, while PMA inhibited...
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Zona Hardening of Mouse Oocytes Undergone Meiotic Resumption In Vivo

Kim JS, Kim HK, Park JM, Lee SJ, Lee JY, Kim MK

  • KMID: 1930550
  • Korean J Fertil Steril.
  • 1997 Apr;24(1):1-11.
It is well known that the bona pellucidae of mouse oocytes become 'hardened' when they are allowed to mature in vitro in the absence of serum components. To see if...
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Effects of Nitric Oxide on the Maturation of Mouse Oocyte in vitro

Kim JL, Lee KY, Park HJ, Kwon YS, Lee YI

  • KMID: 2075948
  • Korean J Obstet Gynecol.
  • 1999 Nov;42(11):2542-2548.
OBJECTIVE: Nitric oxide (NO) produced in ovary may contribute to follicle maturation, ovulation, oocyte maturation and luteinization. In this study, the effect of nitric oxide on the spontaneous maturation of...
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Comparison of regulatory action of cAMP and cGMP on the activation of neutrophil responses

Han CH, Yoon YC, Shin YK, Han ES, Lee CS

  • KMID: 2285164
  • Korean J Physiol Pharmacol.
  • 1997 Feb;1(1):97-105.
The regulatory role of cyclic nucleotides in the expression of neutrophil responses has been examined. fMLP-stimulated superoxide production in neutrophils was inhibited by dibutyryl adenosine 3',5'-cyclic monophosphate (DBcAMP), histamine, adenosine + theophylline, cAMP elevating...
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Physiological Role of PGE2 and DBcAMP in Bone Cell Metabolism

Chae HJ, Chae SW, Kim HR

  • KMID: 1550799
  • Korean J Immunol.
  • 1999 Mar;21(1):77-84.
One of the primary functions for which bones have evolved is to act as a structural support. To achieve this, bones remodel throughout life so that their structure remains optimal...
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Human SNF2L Gene Is Regulated Constitutively and Inducibly in Neural Cells via a cAMP-Response Element

Xia Y, Wang L, Ma C, Gong Y, Zhao Y

PURPOSE: SNF2L belongs to Imitation Switch family and plays an essential role in neural tissues and gonads. In our previous studies, we have demonstrated that the basal transcription of human...
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Effects of Melatonin on the Meiotic Maturation of Mouse Oocytes in vitro

Ahn HJ, Bae IH

  • KMID: 2085162
  • Korean J Fertil Steril.
  • 2004 Sep;31(3):155-168.
OBJECTIVE: Melatonin, which is secreted by pineal gland play an important role in the regulation of ovarian function via seasonal rhythm and sleep in most mammals. It also has a...
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Regulatory role of cyclic nucleotides in non-adrenergic non-cholinergic relaxation of lower esophageal sphincter from dogs

Kim YT, Rhim BY

  • KMID: 2285174
  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):303-313.
The role of the lower esophageal sphincter (LES) is characterized by the ability to maintain tone and to relax allowing the passage of a bolus. It is known that LES relaxation during...
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Effect and Mechanism of Growth Factors and Their Interactions on the Expression of c-fos and c-myc Proto-oncogenes in Cultured Normal Rat Thyroid Cell Line (FRTL-5)

Yoo HY, Oh SK

  • KMID: 2206227
  • J Korean Surg Soc.
  • 1997 Jun;52(6):771-784.
Oncogenes are known to be involved in normal cellular growth and proliferation as well as in carcinogenesis. It is reported that stimulation of quiescent cells with growth factors makes the...
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CD99 type II is a determining factor for the differentiation of primitive neuroectodermal cells

Lee EJ, Lee HG, Park SH, Choi EY, Park SH

  • KMID: 1093617
  • Exp Mol Med.
  • 2003 Oct;35(5):438-447.
CD99 is a 32-kDa cell surface molecule present on thymocytes, peripheral T cells, many other hematopoietic stem cells and somatic cells were implicated in cell-cell adhesion and cell-activation phenomena. Two...
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Cholera toxin mediated regulation of the expression of Gq alpha and G11 alpha GTP binding proteins

Shah BH

  • KMID: 1029937
  • Exp Mol Med.
  • 1999 Jun;31(2):89-94.
Previously it has been shown that persistent activation of the stimulatory adenylyl cyclase pathway with cholera toxin (CT) downregulates the Gs alpha polypeptide (80%) in a cAMP-independent manner in C6 glioma cells...
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Phosphorylation of phospholipase D1 and the modulation of its interaction with RhoA by cAMP-dependent protein kinase

Jang MJ, Lee MJ, Park HY, Bae YS, Min DS, Ryu SH, Kwak JY

  • KMID: 1380212
  • Exp Mol Med.
  • 2004 Apr;36(2):172-178.
Agents that elevate cellular cAMP are known to inhibit the activation of phospholipase D (PLD). We investigated whether PLD can be phosphorylated by cAMP-dependent protein kinase (PKA) and PKA-mediated phosphorylation...
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