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Clinical Features and Culprit Food Allergens of Korean Adult Food Allergy Patients: A Cross-Sectional Single-Institute Study

Lee SC, Kim SR, Park KH, Lee JH, Park JW

PURPOSE: To investigate the causative allergens and clinical characteristics of Korean adult patients with food allergy (FA). METHODS: This retrospective, cross-sectional single-institutional study enrolled Korean adult patients (n = 812) suspected...
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Anti-obesity and LDL-cholesterol lowering effects of silkworm hemolymph in C57BL/6N mice fed high fat diet

Nam YR, Ko YE, Ly SY

PURPOSE: Obesity, a worldwide epidemic, is associated with insulin resistance, hyperlipidemia, hypertension, cardiovascular disease, and certain cancers. Many strategies, including natural alternative anti-obesity agents, are used widely to prevent obesity....
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The effects of proteins released from silk mat layers on macrophages

Kim JW, Jo YY, Kweon HY, Kim DW, Kim SG

BACKGROUND: The objective of this study was to evaluate the changes in gene expression after incubation of cells with proteins released from different silk mat layers. METHODS: A silk cocoon from...
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Lipolytic effect of novel extracts from mulberry (Morus alba) leaves fermented with Cordyceps militaris in the primary adipocytes derived from SD rats

Lee MR, Kim JE, Yun WB, Choi JY, Park JJ, Kim HR, Song BR, Choi YW, Kim KM, Hwang DY

Mulberry (Morus alba) leaves are known to have therapeutic effects on lipid metabolism including lipogenesis, lipolysis and hyperlipidemia. However, novel compounds with strong lipolytic ability among 27 extracts of the...
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Protective Effect of Boiled and Freeze-dried Mature Silkworm Larval Powder Against Diethylnitrosamine-induced Hepatotoxicity in Mice

Cho JM, Kim KY, Ji SD, Kim EH

BACKGROUND: Hepatocellular carcinoma (HCC) is a representative inflammation-associated cancer and known to be the most frequent tumors. HCC may also induce important pro- and anti-tumor immune reactions. However, the underlying...
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Allergenic Characterization of 27-kDa Glycoprotein, a Novel Heat Stable Allergen, from the Pupa of Silkworm, Bombyx mori

Jeong KY, Son M, Lee JY, Park KH, Lee JH, Park JW

Boiled silkworm pupa is a traditional food in Asia, and patients with silkworm pupa food allergy are common in these regions. Still now only one allergen from silkworm, arginine kinase,...
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Protein Expression of the Bombyx mori Decapentaplegic Gene using the Baculovirus Expression Vector System

Jeong ST, Park SW

The Bombyx mori decapentaplegic gene is one of the conserved genes in vertebrate and invertebrates. The TGF-beta superfamily contains conserved polypeptide growth factors that play important roles in different cellular...
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Entomopathogenicity of Simplicillium lanosoniveum Isolated in Korea

Lim SY, Lee S, Kong HG, Lee J

Fruiting bodies similar to those of the ascomycete fungi Podostroma cornu-damae and Cordyceps militaris were collected from Mt. Seunghak in Busan, Korea on August 21, 2012. The fruiting bodies were...
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Powdered Wound Dressing Materials Made from wild Silkworm Antheraea pernyi Silk Fibroin on Full-skin Thickness Burn Wounds on Rats

Kim MK, Yoo KY, Kwon KJ, Kim SG, Park YW, Lee KG, Jo YY, Kweon HY

  • KMID: 1910871
  • Maxillofac Plast Reconstr Surg.
  • 2014 May;36(3):111-115.
PURPOSE: This study evaluated powdered burn wound dressing materials from wild silkworm fibroin in an animal model. METHODS: Fifteen rats were used in this experiment. Full-thickness 2x2 cm burn wounds were...
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Effect of repeated Paecilomyces japonica treatment on rats

Kim YB, Hong DH, Cho ES, Im W, Kim IH, Son HY

  • KMID: 1700788
  • Korean J Vet Res.
  • 2014 Mar;54(1):31-38.
Cordyceps is a fungus used as a traditional medicine in China, Japan, and Korea. Paecilomyces (P.) japonica is a new cordyceps that was recently cultivated on silkworm pupae in Korea....
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Evaluation of General Toxicity and Genotoxicity of the Silkworm Extract Powder

Heo HS, Choi JH, Oh JJ, Lee WJ, Kim SS, Lee DH, Lee HK, Song SW, Kim KH, Choi YK, Ryu KS, Kang BH

  • KMID: 2317845
  • Toxicol Res.
  • 2013 Dec;29(4):263-278.
The silkworm extract powder contain 1-deoxynojirimycin (DNJ), a potent alpha-glycosidase inhibitor, has therapeutic potency against diabetes mellitus. Therefore, natural products containing DNJ from mulberry leaves and silkworm are consumed as...
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Red ginseng extract increases the functional components of silkworm Bombyx mori L. used as an anti-diabetes medicinal resource

Son MW, Moon DI, Shin EH, Oh HG, Hong S, Han SJ, Lee HA, Chung YH, Kim O

  • KMID: 2055095
  • J Biomed Res.
  • 2013 Mar;14(1):40-46.
The anti-diabetes mechanism of silkworm Bombyx mori L. powder and extracts was found to inhibit the activity of alpha-glycosidase. The major functional component of silkworm powder was 1-deoxynojirimycin (1-DNJ), which...
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Anti-obesity effects of Rapha diet(R) preparation in mice fed a high-fat diet

Kim J, Kyung J, Kim D, Choi EK, Bang P, Park D, Kim YB

The anti-obesity activities of Rapha diet(R) preparation containing silkworm pupa peptide, Garcinia cambogia, white bean extract, mango extract, raspberry extract, cocoa extract, and green tea extract were investigated in mice...
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Effects of male silkworm pupa powder on the erectile dysfunction by chronic ethanol consumption in rats

Oh HG, Lee HY, Kim JH, Kang YR, Moon DI, Seo MY, Back HI, Kim SY, Oh MR, Park SH, Kim MG, Jeon JY, Shin SJ, Ryu KS, Chae SW, Kim O, Park JK

Erectile dysfunction (ED) is a highly prevalent disorder that affects millions of men worldwide. ED is now considered an early manifestation of atherosclerosis, and consequently, a precursor of systemic vascular...
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Synnemata Production Using Silkworm Variety, Female Yangwonjam by Isaria tenuipes

Ji SD, Sung GB, Kang PD, Kim KY, Choi YS, Kim NS, Woo SO, Han SM, Hong IP, Ha NG

  • KMID: 2312635
  • Mycobiology.
  • 2011 Sep;39(3):158-163.
This study was conducted to confirm the possible use of female Yangwonjam as a host for synnemata production of Isaria tenuipes in eight local areas in Korea. Silkworm pupation rate,...
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Resistance to Toxoplasma gondii Infection in Mice Treated with Silk Protein by Enhanced Immune Responses

Moon JH, Pyo KH, Jung BK, Chun HS, Chai JY, Shin EH

This study investigated whether elevated host immune capacity can inhibit T. gondii infection. For this purpose, we used silk protein extracted from Bombyx mori cocoons as a natural supplement to...
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Effects of a Silkworm Extract on Dopamine and Monoamine Oxidase-B Activity in an MPTP-induced Parkinsons Disease Model

Kang YK, Oh HS, Cho YH, Kim YJ, Han YG, Nam SH

  • KMID: 2312079
  • Lab Anim Res.
  • 2010 Sep;26(3):287-292.
The protective efficacy of a silkworm extract (SE) on N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinsonism and its possible mechanisms were studied in C57BL/6 mice. Mice were administrated intraperitoneally with SE (20 mg/kg/day) for...
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Breeding of a Silkworm Variety for Synnemata Production of Isaria tenuipes

Kang PD, Sung GB, Kim KY, Kim MJ, Hong IP, Ha NG

This study was conducted out to select a silkworm variety suitable for synnemata production of Isaria tenuipes. Four kinds of the mulberry silkworm varieties, Bombyx mori, were hybridized using a...
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Fruit Body Formation on Silkworm by Cordyceps militaris

Hong IP, Kang PD, Kim KY, Nam SH, Lee MY, Choi YS, Kim NS, Kim HK, Lee KG, Humber RA

  • KMID: 2312579
  • Mycobiology.
  • 2010 Jun;38(2):128-132.
Injection inoculation protocols for fruit body formation of Cordyceps militaris (C. militaris) were investigated to improve the incidence of infection in the silkworm species Bombyx mori (B. mori). Injection, with...
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Chemical Components of Paecilomyces tenuipes (Peck) Samson

Hong IP, Nam SH, Sung GB, Chung IM, Hur H, Lee MW, Kim MK, Guo SX

  • KMID: 2312533
  • Mycobiology.
  • 2007 Dec;35(4):215-218.
The caterpillar-shaped Chinese medicinal mushroom (DongChongXiaCao) looks like a worm in the winter and like a grass in the summer. The fruiting body has been regarded as popular folk or...
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