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Liver dysfunction induced by systemic hypersensitivity reaction to lamotrigine: case report

Im SG, Yoo SH, Park YM, Lee SJ, Jang SK, Jeon DO, Cho HJ, Oh MJ

Lamotrigine is an anticonvulsant drug used to treat partial and generalized seizure disorders. Hypersensitivity to lamotrigine usually causes mild symptoms such as fever, rash, and slight invasion of internal organs....
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Effect of phosphorus deficiency on erythrocytic morphology and function in cows

Zhang Z, Bi M, Yang J, Yao H, Liu Z, Xu S

The aim of this study was to evaluate the influence of phosphorus (P) deficiency on the morphological and functional characteristics of erythrocytes in cows. Forty Holstein-Friesian dairy cows in mid-lactation...
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Drug-induced Hepatotoxicity of Anti-tuberculosis Drugs and Their Serum Levels

Jeong I, Park JS, Cho YJ, Yoon HI, Song J, Lee CT, Lee JH

The correlation between serum anti-tuberculosis (TB) drug levels and the drug-induced hepatotoxicity (DIH) remains unclear. The purpose of this study was to investigate whether anti-TB DIH is associated with basal...
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A Korean patient with Guillain-Barré syndrome following acute hepatitis E whose cholestasis resolved with steroid therapy

Ji SB, Lee SS, Jung HC, Kim HJ, Kim HJ, Kim TH, Jung WT, Lee OJ, Song DH

Autochthonous hepatitis E virus (HEV) is an emerging pathogen in developed countries, and several cases of acute HEV infection have been reported in South Korea. However, there have been no...
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The Influence of Alcoholic Liver Disease on Serum PIVKA-II Levels in Patients without Hepatocellular Carcinoma

Kang K, Kim JH, Kang SH, Lee BJ, Seo YS, Yim HJ, Yeon JE, Park JJ, Kim JS, Bak YT, Byun KS

BACKGROUND/AIMS: Prothrombin induced by vitamin K deficiency or antagonist II (PIVKA-II) is a widely used diagnostic marker for hepatocellular carcinoma (HCC). We evaluated the correlation between alcoholic liver disease (ALD)...
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KASL Clinical Practice Guidelines: Management of chronic hepatitis B

The Korean Association for the Study of the Liver (KASL)

No abstract available.
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The levels of liver enzymes and atypical lymphocytes are higher in youth patients with infectious mononucleosis than in preschool children

Wang Y, Li J, Ren YY, Zhao H

BACKGROUND/AIMS: Infectious mononucleosis (IM) is the clinical presentation of primary infection with Epstein-Barr virus. Although the literature contains a massive amount of information on IM, most of this is related...
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Clinical Features of Drug-induced Liver Injury According to Etiology

Lee BM, Lee WC, Jang JY, Ahn P, Kim JN, Jeong SW, Park EJ, Lee SH, Kim SG, Cha SW, Kim YS, Cho YD, Kim HS, Kim BS

Drug-induced liver injury (DILI) is an increasingly common cause of acute hepatitis. We examined clinical features and types of liver injury of 65 affected patients who underwent liver biopsy according...
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Co-development of autoimmune hepatitis and Sjogren's syndrome triggered by the administration of herbal medicines

Oh HJ, Mok YM, Baek MS, Lee JK, Seo BS, Kim TH, Choi KH, Hwang IK, Ra JE, Oh YR, Kim YS, Cho EY, Kim HC, Sohn YW

Autoimmune hepatitis (AIH) has been reported in association with Sjogren's syndrome (SS). Drug-induced AIH has been rarely reported. A rare case of the co-development of AIH and SS in a...
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Three cases of glycogenic hepatopathy mimicking acute and relapsing hepatitis in type I diabetes mellitus

Cha JH, Ra SH, Park YM, Ji YK, Lee JH, Park SY, Baik SK, Kwon SO, Cho MY, Kim MY

Glycogenic hepatopathy (GH) is an uncommon cause of serum transaminase elevation in type I diabetes mellitus (DM). The clinical signs and symptoms of GH are nonspecific, and include abdominal discomfort,...
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Durability after discontinuation of nucleos(t)ide therapy in chronic HBeAg negative hepatitis patients

Kim YJ, Kim K, Hwang SH, Kim SS, Lee D, Cheong JY, Cho SW

BACKGROUND/AIMS: Relapse has been reported after stopping nucleos(t)ide (NUC) therapy in the majority of chronic HBeAg negative hepatitis patients. However, the ideal treatment duration of HBeAg negative chronic hepatitis B...
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Determinants of Brachial-Ankle Pulse Wave Velocity in Normotensive Young Adults with Type 2 Diabetes Mellitus

Choi BG, Kang JH, Jeon YK, Kim SS, Lee CW, Kim IJ, Kim YK, Kim BH

Brachial-ankle pulse wave velocity (baPWV) is simple, noninvasive method which correlates well with arterial stiffness. Herein, we assessed the determinants of baPWV in normotensive young adults with type 2 diabetes....
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Early monitoring for detection of antituberculous drug-induced hepatotoxicity

Lee CM, Lee SS, Lee JM, Cho HC, Kim WS, Kim HJ, Ha CY, Kim HJ, Kim TH, Jung WT, Lee OJ

BACKGROUND/AIMS: We investigated the time of onset of antituberculous drug-induced hepatotoxicity (ADIH) and related characteristics. METHODS: Adult patients (n = 1,031) treated with first-line antituberculous drugs between February 2009 and January...
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Physical Activity- and Alcohol-dependent Association Between Air Pollution Exposure and Elevated Liver Enzyme Levels: An Elderly Panel Study

Kim KN, Lee H, Kim JH, Jung K, Lim YH, Hong YC

OBJECTIVES: The deleterious effects of air pollution on various health outcomes have been demonstrated. However, few studies have examined the effects of air pollution on liver enzyme levels. METHODS: Blood samples...
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Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high-yielding dairy cows

Gonzalez F, Muino R, Pereira V, Campos R, Benedito J

Blood indicators are used as a tool to diagnose metabolic disorders. The present work was conducted to study the relationships among blood indicators of lipomobilization and hepatic function in high-yielding...
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Doxazosin Treatment Attenuates Carbon Tetrachloride-Induced Liver Fibrosis in Hamsters through a Decrease in Transforming Growth Factor beta Secretion

Munoz-Ortega MH, Llamas-Ramirez RW, Romero-Delgadillo NI, Elias-Flores TG, de Jesus Tavares-Rodriguez E, del Rosario Campos-Esparza M, Cervantes-Garcia D, Munoz-Fernandez L, Gerardo-Rodriguez M, Ventura-Juarez J

BACKGROUND/AIMS: The development of therapeutic strategies for the treatment of cirrhosis has become an important focus for basic and clinical researchers. Adrenergic receptor antagonists have been evaluated as antifibrotic drugs...
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Efficacy and safety of daclatasvir and asunaprevir for hepatitis C virus genotype 1b infection

Nam HC, Lee HL, Yang H, Song MJ

BACKGROUND/AIMS: The treatment strategy for hepatitis C virus (HCV) has been changing rapidly since the introduction of direct-acting antivirals such as daclatasvir (DCV) and asunaprevir (ASV). We evaluated the efficacy...
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A case of rhabdomyolysis during hospitalization for acute hepatitis A

Ann SH, An GH, Lee SY, Oak JH, Moon HI, Moon SK, Han NI, Lee YS

A 29-year-old man was admitted to hospital with fever, myalgia, and sore throat. Initial laboratory findings were compatible with acute hepatitis; he was positive for the serologic marker for acute...
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Carbohydrate-deficient Transferrin as a Marker of Heavy Drinking in Korean Males

Kim SM, Kim JS, Kim KM, Pack HJ, Lee DH, Kim SS, Jung JG

This study was performed to evaluate the usefulness of carbohydrate-deficient transferrin (CDT) as a marker of heavy drinking in Korean males. The subjects (143 Korean males) were classified into 2...
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Hypoadiponectinemia and Insulin Resistance are Associated with Nonalcoholic Fatty Liver Disease

Yoon D, Lee SH, Park HS, Lee JH, Park JS, Cho KH, Kim SM

We investigated the association between nonalcoholic fatty liver disease (NAFLD) and plasma adiponectin levels and insulin resistance. We recruited study subjects among one hundred and eighty one persons who were...
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