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No association of prion protein gene polymorphisms with Alzheimer's disease in Korean population

Ahn K, Kim E, Kwon YA, Kim DK, Lee JE, Jo SA

  • KMID: 1115951
  • Exp Mol Med.
  • 2006 Dec;38(6):727-731.
The polymorphism at codon 129 (M129V) of the human prion protein gene (PRNP) is a known risk factor for Creutzfeldt-Jakob disease (CJD) in Caucasians. There are few reports of this...
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Apolipoprotein E polymorphism in non-diabetic patients with acute coronary syndrome

Kim IJ, Hong BK, Lee BK, Kwon HM, Kim D, Choi EY, Byun KH, Kim JH, Song KS, Kim HS

Since a decade ago, apolipoprotein (apo) E polymorphism has been focussed as a risk factor for cardiovascular disease. ApoE plays a central role as a receptor ligand for...
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A reconstituted HDL containing V156K or R173C apoA-I exhibited anti-inflammatory activity in apo-E deficient mice and showed resistance to myeloperoxidase-mediated oxidation

Cho KH, Kim JR

It has been hypothesized that blood infusion of reconstituted HDL (rHDL) is a possible therapeutic strategy for the treatment of coronary artery disese. To compare short-term anti-inflammatory activity of wildtype...
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Ginkgo biloba extract (GbE) enhances the anti-atherogenic effect of cilostazol by inhibiting ROS generation

Jung IH, Lee YH, Yoo JY, Jeong SJ, Sonn SK, Park JG, Ryu KH, Lee BY, Han HY, Lee SY, Kim DY, Lee H, Oh GT

  • KMID: 1383792
  • Exp Mol Med.
  • 2012 May;44(5):311-318.
In this study, the synergistic effect of 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl) butoxy]-3,4-dihydro-2(1H)-quinolinone (cilostazol) and Ginkgo biloba extract (GbE) was examined in apolipoprotein E (ApoE) null mice. Co-treatment with GbE and cilostazol synergistically decreased...
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