- Inhibitory Effect of Rosae Multiflorae Fructus Extracts on the Receptor Activator of NF-κB Ligand-Induced Osteoclastogenesis through Modulation of P38- and Ca2âº-Mediated Nuclear Factor of Activated T-Cells Cytoplasmic 1 Expression
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Park KH, Gu DR, Kim MS, Lee SH
- KMID: 2471314
- J Bone Metab.
- 2020 Feb;27(1):53-63.
- doi: 10.11005/jbm.2020.27.1.53
BACKGROUND: Rosae Multiflorae fructus (RMF), known to have anti-inflammatory and antioxidant properties, has been used as a traditional remedy for inflammatory diseases such as arthritis in Eastern Asia. However, its... -
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- Spreading Shape and Area Regulate the Osteogenesis of Mesenchymal Stem Cells
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Zhao Y, Sun Q, Wang S, Huo B
- KMID: 2467050
- Tissue Eng Regen Med.
- 2019 Dec;16(6):573-583.
- doi: 10.1007/s13770-019-00213-y
BACKGROUND: Mesenchymal stem cells (MSCs) have strong self-renewal ability and multiple differentiation potential. Some studies confirmed that spreading shape and area of single MSCs influence cell differentiation, but few studies... -
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- Comparison of the Cardiomyogenic Potency of Human Amniotic Fluid and Bone Marrow Mesenchymal Stem Cells
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Jain M, Minocha E, Tripathy N, Singh N, Chaturvedi CP, Nityanand
- KMID: 2465885
- Int J Stem Cells.
- 2019 Nov;12(3):449-456.
- doi: 10.15283/ijsc18087
BACKGROUND AND OBJECTIVES: Most studies in cardiac regeneration have explored bone marrow mesenchymal stem cells (BM-MSC) with variable therapeutic effects. Amniotic fluid MSC (AF-MSC) having extended self-renewal and multi-potent properties... -
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- Rab25 Deficiency Perturbs Epidermal Differentiation and Skin Barrier Function in Mice
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Jeong H, Lim KM, Goldenring JR, Nam KT
- KMID: 2462882
- Biomol Ther.
- 2019 Nov;27(6):553-561.
- doi: 10.4062/biomolther.2019.125
Rab25, a member of the Rab11 small GTPase family, is central to achieving cellular polarity in epithelial tissues. Rab25 is highly expressed in epithelial cells of various tissues including breast,... -
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- Adiponectin Attenuates the Inflammation in Atopic Dermatitis-Like Reconstructed Human Epidermis
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Seo HS, Seong KH, Kim CD, Seo SJ, Park BC, Kim MH, Hong SP
- KMID: 2439064
- Ann Dermatol.
- 2019 Apr;31(2):186-195.
- doi: 10.5021/ad.2019.31.2.186
BACKGROUND: Atopic dermatitis (AD) is a chronic disorder, with a vicious cycle of repetitive inflammation and deterioration of the epidermal barrier function. Adiponectin, an adipokine, has anti-inflammatory effects on various... -
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- MiR-214 Regulates the Human Hair Follicle Stem Cell Proliferation and Differentiation by Targeting EZH2 and Wnt/β-Catenin Signaling Way In Vitro
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Du KT, Deng JQ, He XG, Liu ZP, Peng C, Zhang MS
- KMID: 2411882
- Tissue Eng Regen Med.
- 2018 Jun;15(3):341-350.
- doi: 10.1007/s13770-018-0118-x
miR-214 plays a major role in the self-renewal of skin tissue. However, whether miR-214 regulates the proliferation and differentiation of human hair follicle stem cells (HFSCs) is unknown. Primary HFSCs... -
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- Effects of 1,25-dihydroxyvitamin D₃ on the differentiation of MC3T3-E1 osteoblast-like cells
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Kim HS, Zheng M, Kim DK, Lee WP, Yu SJ, Kim BO
- KMID: 2405408
- J Periodontal Implant Sci.
- 2018 Feb;48(1):34-46.
- doi: 10.5051/jpis.2018.48.1.34
PURPOSE: The purpose of this study was to evaluate the effects of 1,25-dihydroxyvitamin D₃ on the proliferation, differentiation, and matrix mineralization of MC3T3-E1 osteoblast-like cells in vitro. METHODS: MC3T3-E1 osteoblastic cells... -
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- Establishment of Immortalized Primary Human Foreskin Keratinocytes and Their Application to Toxicity Assessment and Three Dimensional Skin Culture Construction
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Choi M, Park M, Lee S, Lee JW, Cho MC, Noh M, Lee C
- KMID: 2378808
- Biomol Ther.
- 2017 May;25(3):296-307.
- doi: 10.4062/biomolther.2017.043
In spite of frequent usage of primary human foreskin keratinocytes (HFKs) in the study of skin biology, senescence-induced blockage of in vitro proliferation has been a big hurdle for their... -
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- Kinetin Improves Barrier Function of the Skin by Modulating Keratinocyte Differentiation Markers
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An S, Cha HJ, Ko JM, Han H, Kim SY, Kim KS, Lee SJ, An IS, Kim S, Youn HJ, Ahn KJ, Kim SY
- KMID: 2368021
- Ann Dermatol.
- 2017 Feb;29(1):6-12.
- doi: 10.5021/ad.2017.29.1.6
BACKGROUND: Kinetin is a plant hormone that regulates growth and differentiation. Keratinocytes, the basic building blocks of the epidermis, function in maintaining the skin barrier. OBJECTIVE: We examined whether kinetin induces... -
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- Derivation and Differentiation of Bone Marrow Mesenchymal Stem Cells from Osteoarthritis Patients
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Gari M, Alsehli H, Gari A, Abbas M, Alkaff M, Abuzinadah M, Al-Sayes F, Gari M, Dallol A, Abuzenadah AM, Gauthaman
- KMID: 2360885
- Tissue Eng Regen Med.
- 2016 Dec;13(6):732-739.
- doi: 10.1007/s13770-016-0013-2
Osteoarthritis (OA) of the knee is a degenerative joint disease caused by the progressive reduction of the articular cartilage surface that leads to reduced joint function. Cartilage degeneration occurs through... -
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- In vitro characterization of human dental pulp stem cells isolated by three different methods
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Jang JH, Lee HW, Cho KM, Shin HW, Kang MK, Park SH, Kim E
- KMID: 2356005
- Restor Dent Endod.
- 2016 Nov;41(4):283-295.
- doi: 10.5395/rde.2016.41.4.283
OBJECTIVES: In this study, we characterized human dental pulp cells (HDPCs) obtained by different culture methods to establish the most suitable methodology for dental tissue engineering and regenerative endodontic applications. MATERIALS... -
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- Potential Role of S100A8 in Cutaneous Squamous Cell Carcinoma Differentiation
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Shin JM, Chang IK, Lee YH, Yeo MK, Kim JM, Sohn KC, Im M, Seo YJ, Kim CD, Lee JH, Lee Y
- KMID: 2171374
- Ann Dermatol.
- 2016 Apr;28(2):179-185.
- doi: 10.5021/ad.2016.28.2.179
BACKGROUND: S100A8 is differentially expressed in various cell types and is associated with a number of malignant disorders. S100A8 may affect tumor biology. However, its role in cutaneous squamous cell... -
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- Effect of Fibroblast Growth Factor-2 and Retinoic Acid on Lineage Commitment of Bone Marrow Mesenchymal Stem Cells
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Lim J, Park EK
- KMID: 2360866
- Tissue Eng Regen Med.
- 2016 Feb;13(1):47-56.
- doi: 10.1007/s13770-016-9102-0
In this study, we examined the effect of a combination of fibroblast growth factor-2 (FGF-2) and retinoic acid (RA) on osteoblast and adipocyte lineage commitment and differentiation of human bone... -
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- Sarcomatoid cholangiocarcinoma with osteoclast-like giant cells associated with hepatolithiasis: A case report
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Kim HM, Kim H, Park YN
- KMID: 2351032
- Clin Mol Hepatol.
- 2015 Sep;21(3):309-313.
- doi: 10.3350/cmh.2015.21.3.309
No abstract available. -
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- Stimulation of keratinocyte differentiation by extract of combined medicinal plant
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Li XM, Choi DK, Lim SK, Ahn IS, Kim DI, Piao YJ, Kim CD, Lee JH
- KMID: 2168996
- J Biomed Res.
- 2014 Dec;15(4):176-181.
- doi: 10.12729/jbr.2014.15.4.176
Skin is the outermost organ and acts as a barrier between the organism and environment. Skin protects the organism from environmental insults, such as chemicals, pathogens, and UV light. Much... -
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- miR-18a-5p MicroRNA Increases Vascular Smooth Muscle Cell Differentiation by Downregulating Syndecan4
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Kee HJ, Kim GR, Cho SN, Kwon JS, Ahn Y, Kook H, Jeong MH
- KMID: 2223887
- Korean Circ J.
- 2014 Jul;44(4):255-263.
- doi: 10.4070/kcj.2014.44.4.255
BACKGROUND AND OBJECTIVES: Differentiation and de-differentiation of vascular smooth muscle cells (VSMCs) are important events in atherosclerosis and restenosis after angioplasty. MicroRNAs are considered a key regulator in cellular processes... -
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- Ameliorative Effect of Bone Marrow-Derived Stem Cells on Injured Liver of Mice Infected with Schistosoma mansoni
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El-Mahdi M, Mansour WA, Hammam O, Mehana NA, Hussein TM
- KMID: 1792162
- Korean J Parasitol.
- 2014 Apr;52(2):151-162.
The technique of stem cells or hepatocytes transplantation has recently improved in order to bridge the time before whole-organ liver transplantation. In the present study, unfractionated bone marrow stem cells... -
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- Nectandrin A Enhances the BMP-Induced Osteoblastic Differentiation and Mineralization by Activation of p38 MAPK-Smad Signaling Pathway
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Kim DY, Kim GW, Chung SH
- KMID: 1500241
- Korean J Physiol Pharmacol.
- 2013 Oct;17(5):447-453.
- doi: 10.4196/kjpp.2013.17.5.447
Osteoblastic activity of nectandrin A was examined in C2C12 cells. Nectandrin A enhances the BMP-induced osteoblastic differentiation and mineralization, manifested by the up-regulation of differentiation markers (alkaline phosphatase and osteogenic... -
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- Expression of Thyroid Stimulating Hormone Receptor mRNA in Mouse C2C12 Skeletal Muscle Cells
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Ohn JH, Han SK, Park DJ, Park KS, Park YJ
- KMID: 1973810
- Endocrinol Metab.
- 2013 Jun;28(2):119-124.
- doi: 10.3803/EnM.2013.28.2.119
BACKGROUND: We analyzed whether thyroid stimulating hormone receptor (TSH-R) is expressed in a skeletal muscle cell line and if TSH has influence on the differentiation of muscle cells or on... -
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- Analysis of Molecular Expression in Adipose Tissue-Derived Mesenchymal Stem Cells : Prospects for Use in the Treatment of Intervertebral Disc Degeneration
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Jin ES, Min J, Jeon SR, Choi KH, Jeong JH
- KMID: 1426205
- J Korean Neurosurg Soc.
- 2013 Apr;53(4):207-212.
- doi: 10.3340/jkns.2013.53.4.207
OBJECTIVE: Recent studies have shown encouraging progress toward the use of autogenic and allogenic mesenchymal stem cells (MSCs) to arrest, or even lead to partial regeneration in, intervertebral disc (IVD)... -
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