- CD36, a scavenger receptor implicated in atherosclerosis
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Park YM
- KMID: 2155364
- Exp Mol Med.
- 2014 Jun;46(6):e99.
- doi: 10.1038/emm.2014.38
CD36 is a membrane glycoprotein that is present on various types of cells, including monocytes, macrophages, microvascular endothelial cells, adipocytes and platelets. Macrophage CD36 participates in atherosclerotic arterial lesion formation... -
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- Purification of thrombospondin receptor (CD36) from human platelet membrane
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Kim JH, Suk KH, Park NY, Kim SH
- KMID: 2128623
- Exp Mol Med.
- 1997 Mar;29(1):31-34.
Thrombospondin receptor (CD36) has been recently identified in platelets and various cell lines as the receptor for thrombospondin, an adhesive protein required for irreversible aggregation of platelets as well as... -
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- The Glucotoxicity Protecting Effect of Ezetimibe in Pancreatic Beta Cells via Inhibition of CD36
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Yoon JS, Moon JS, Kim YW, Won KC, Lee HW
- KMID: 2363693
- J Korean Med Sci.
- 2016 Apr;31(4):547-552.
- doi: 10.3346/jkms.2016.31.4.547
Inhibition of CD36, a fatty acid transporter, has been reported to prevent glucotoxicity and ameliorate high glucose induced beta cell dysfunction. Ezetimibe is a selective cholesterol absorption inhibitor that blocks... -
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- Plasma CD36 and Incident Diabetes: A Case-Cohort Study in Danish Men and Women
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Wang Y, Zhu J, Aroner S, Overvad K, Cai T, Yang M, Tjønneland A, Handberg A, Jensen MK
- KMID: 2470962
- Diabetes Metab J.
- 2020 Feb;44(1):134-142.
- doi: 10.4093/dmj.2018.0273
BACKGROUND: Membrane CD36 is a fatty acid transporter implicated in the pathogenesis of metabolic disease. We aimed to evaluate the association between plasma CD36 levels and diabetes risk and to... -
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- CD36 signaling inhibits the translation of heat shock protein 70 induced by oxidized low density lipoprotein through activation of peroxisome proliferators-activated receptor gamma
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Lee KJ, Ha ES, Kim MK, Lee SH, Suh JS, Lee SH, Park KH, Park JH, Kim DJ, Kang D, Kim BC, Jeoung D, Kim YK, Kim HD, Hahn JH
- KMID: 1072946
- Exp Mol Med.
- 2008 Dec;40(6):658-668.
- doi: 10.3858/emm.2008.40.6.658
Oxidized LDL (OxLDL), a causal factor in atherosclerosis, induces the expression of heat shock proteins (Hsp) in a variety of cells. In this study, we investigated the role of CD36,... -
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- Ox-LDL suppresses PMA-induced MMP-9 expression and activity through CD36-mediated activation of PPAR-gamma
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Lee KJ, Kim HA, Kim PH, Lee HS, Ma KR, Park JH, Kim DJ, Hahn JH
- KMID: 1103320
- Exp Mol Med.
- 2004 Dec;36(6):534-544.
During chronic inflammatory response, mono- cytes/macrophages produce 92-kDa matrix metalloproteinase-9 (MMP-9), which may contribute to their extravasation, migration and tissue remodeling. Activation of peroxisome proliferator- activated factor receptor-gamma (PPAR-gamma) has... -
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- Characterization of Binding and Phagocytosis of Oxidatively Damaged Erythrocyte to Macrophage
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Ko HS, Kim IS, Lee KJ, Kim SW, Kim CJ, Ryu WS
- KMID: 759614
- Korean J Intern Med.
- 2002 Dec;17(4):220-226.
BACKGROUND: Scavenger receptors are thought to be involved in the recognition of oxidized low-density lipoprotein (oxLDL) and oxidized erythrocyte (oxRBC). However, there are controversies about the kind of receptors... -
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- Topology of Scavenger Receptor Class B Type I (SR-BI) on Brush Border Membrane
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Han CH, Lee MH
- KMID: 1097342
- J Vet Sci.
- 2002 Dec;3(4):265-272.
Both hydropathy plot and in vitro translation results predict the topology of SR-BI; the receptor is an integral membrane protein of 509 amino acids, consisting of a short cytoplasmic N-terminus... -
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