- Liver dysfunction induced by systemic hypersensitivity reaction to lamotrigine: case report
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Im SG, Yoo SH, Park YM, Lee SJ, Jang SK, Jeon DO, Cho HJ, Oh MJ
- KMID: 2164369
- Clin Mol Hepatol.
- 2015 Jun;21(2):180-182.
- doi: 10.3350/cmh.2015.21.2.180
Lamotrigine is an anticonvulsant drug used to treat partial and generalized seizure disorders. Hypersensitivity to lamotrigine usually causes mild symptoms such as fever, rash, and slight invasion of internal organs.... -
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- Absence of HLA-B*1502 and HLA-A*3101 Alleles in 9 Korean Patients With Antiepileptic Drug-Induced Skin Rash: A Preliminary Study
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Song JS, Kang ES, Joo EY, Hong SB, Seo DW, Lee SY
- KMID: 1791952
- Ann Lab Med.
- 2014 Sep;34(5):372-375.
- doi: 10.3343/alm.2014.34.5.372
There have been a number of studies about correlations between HLA genotypes in various ethnic groups and occurrence of various cutaneous adverse drug reactions, ranging in intensity from mild to... -
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- Phenytoin-Induced Gingival Overgrowth in Un-Cooperated Epilepsy Patients
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Marakoglu , Gursoy UK, Cakmak H, Marakoglu
- KMID: 2428333
- Yonsei Med J.
- 2004 Apr;45(2):337-340.
Phenytoin-induced gingival overgrowth is a well-known and frequently reported gingival lesion, which was first detected in 1939. However, there are conflicts in the literature about the agents which affect the... -
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- HLA Allele Frequencies in 5802 Koreans: Varied Allele Types Associated with SJS/TEN According to Culprit Drugs
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Park HJ, Kim YJ, Kim DH, Kim J, Park KH, Park JW, Lee JH
- KMID: 2466360
- Yonsei Med J.
- 2016 Jan;57(1):118-126.
- doi: 10.3349/ymj.2016.57.1.118
PURPOSE: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are very serious forms of drug-induced cutaneous adverse reaction. SJS/TEN induced by certain drug is well known to be associated with... -
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- Anticonvulsant Hypersensitivity Syndrome Associated with Epstein-Barr Virus Reactivation
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Chang JY, Kim SC
- KMID: 1779537
- Yonsei Med J.
- 2007 Apr;48(2):317-320.
- doi: 10.3349/ymj.2007.48.2.317
We describe a 59-year-old female with severe anticonvulsant hypersensitivity syndrome (AHS) associated with Epstein- Barr virus (EBV) infection. The causative drug was speculated to be carbamazepine. Recurrent EBV infection was... -
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