- Bile Acid Diarrhea: Prevalence, Pathogenesis, and Therapy
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Camilleri
- KMID: 2155640
- Gut Liver.
- 2015 May;9(3):332-339.
- doi: 10.5009/gnl14397
Bile acid diarrhea (BAD) is usually seen in patients with ileal Crohn's disease or ileal resection. However, 25% to 50% of patients with functional diarrhea or diarrhea-predominant irritable bowel syndrome... -
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- HMG CoA Reductase Inhibitors Inhibit HCV RNA Replication of HCV Genotype 1b but Not 2a
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Chang KS, Jo HJ
- KMID: 2168627
- J Bacteriol Virol.
- 2011 Jun;41(2):99-108.
- doi: 10.4167/jbv.2011.41.2.99
Replication of hepatitis C virus (HCV) is regulated by statin, one of 3-hydroxy-3-methylglutaryl CoA reducatase (HMG CoA reductase) inhibitors that block mevalonate pathway and cholesterol biosyntheis, which has been used... -
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- Reversible Dysphasia and Statins
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Davies GR
- KMID: 2157911
- J Korean Med Sci.
- 2012 Apr;27(4):458-459.
- doi: 10.3346/jkms.2012.27.4.458
This paper presents a case of reversible dysphasia occurring in a patient prescribed atorvastatin in combination with indapamide. A milder dysphasia recurred with the prescription of rosuvastatin and was documented... -
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- The Glucotoxicity Protecting Effect of Ezetimibe in Pancreatic Beta Cells via Inhibition of CD36
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Yoon JS, Moon JS, Kim YW, Won KC, Lee HW
- KMID: 2363693
- J Korean Med Sci.
- 2016 Apr;31(4):547-552.
- doi: 10.3346/jkms.2016.31.4.547
Inhibition of CD36, a fatty acid transporter, has been reported to prevent glucotoxicity and ameliorate high glucose induced beta cell dysfunction. Ezetimibe is a selective cholesterol absorption inhibitor that blocks... -
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- Biomedical Issues of Dietary fiber beta-Glucan
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Kim SY, Song HJ, Lee YY, Cho KH, Roh YK
- KMID: 1781892
- J Korean Med Sci.
- 2006 Oct;21(5):781-789.
- doi: 10.3346/jkms.2006.21.5.781
beta-Glucan is a polysaccharide in the form of fiber and the main element of fiber in grains such as barley, oats, yeast and mushrooms. Many studies have examined the efficacy... -
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- Effects of Combined Therapy with Ezetimibe Plus Simvastatin After Drug-Eluting Stent Implantation in a Porcine Coronary Restenosis Model
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Cho JS, Jeong MH, Sim DS, Hong YJ, Lim KS, Kim JH, Kim HD, Baek JY, Yoon HJ, Her SH, Jin SW, Kim JH, Ahn Y, Cho JG, Park JC, Kang JC
- KMID: 1713955
- J Korean Med Sci.
- 2010 May;25(5):716-722.
- doi: 10.3346/jkms.2010.25.5.716
The aim of this study was to examine the anti-proliferative and anti-inflammatory effects of ezetimibe/simvastatin (E/S) after drug-eluting stent (DES) implantation in a porcine coronary restenosis model. Pigs were randomized... -
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- Flexible Initial Dosing of Atorvastatin Based Upon Initial Low-Density Lipoprotein Cholesterol Levels in Type 2 Diabetic Patients
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Atorvastatin Study Group in Korea
- KMID: 1382658
- Korean J Intern Med.
- 2008 Mar;23(1):22-29.
- doi: 10.3904/kjim.2008.23.1.22
BACKGROUND/AIMS: We used flexible starting doses and early titration of atorvastatin to determine the rate of achievement of a low-density lipoprotein cholesterol (LDL-C) target for hyperlipidemic patients with type... -
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- Simvastatin inhibits osteoclast differentiation by scavenging reactive oxygen species
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Moon HJ, Kim SE, Yun YP, Hwang YS, Bang JB, Park JH, Kwon IK
- KMID: 1025163
- Exp Mol Med.
- 2011 Nov;43(11):605-612.
- doi: 10.3858/emm.2011.43.11.067
Osteoclasts, together with osteoblasts, control the amount of bone tissue and regulate bone remodeling. Osteoclast differentiation is an important factor related to the pathogenesis of bone-loss related diseases. Reactive oxygen... -
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- Simvastatin inhibits induction of matrix metalloproteinase-9 in rat alveolar macrophages exposed to cigarette smoke extract
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Kim SE, Thuy TT, Lee JH, Ro JY, Bae YA, Kong Y, Ahn JY, Lee DS, Oh YM, Lee SD, Lee YS
- KMID: 1088603
- Exp Mol Med.
- 2009 Apr;41(4):277-287.
- doi: 10.3858/emm.2009.41.4.031
Matrix metalloproteinase-9 (MMP-9) may play an important role in emphysematous change in chronic obstructive pulmonary disease (COPD), one of the leading causes of mortality and morbidity worldwide. We previously reported... -
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