- Higher Binding Affinity and In Vitro Potency of Reslizumab for Interleukin-5 Compared With Mepolizumab
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Liddament , Husten J, Estephan T, Laine D, Mabon D, Pukac L, Lyons J, Clarke AW, Doyle A
- KMID: 2431860
- Allergy Asthma Immunol Res.
- 2019 Mar;11(2):291-298.
- doi: 10.4168/aair.2019.11.2.291
Reslizumab and mepolizumab are recently approved monoclonal antibodies for the treatment of severe (uncontrolled) eosinophilic asthma. Both are effective in neutralizing the function of interleukin-5 (IL-5). This study is the... -
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- Conversion of a murine monoclonal antibody A13 targeting epidermal growth factor receptor to a human monoclonal antibody by guided selection
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Chang KH, Kim MS, Hong GW, Shin YN, Kim SH
- KMID: 1120142
- Exp Mol Med.
- 2012 Jan;44(1):52-59.
- doi: 10.3858/emm.2012.44.1.005
Epidermal growth factor receptor (EGFR) is an attractive target for tumor therapy because it is overexpressed in the majority of solid tumors and the increase in receptor expression levels has... -
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- Characterization of a novel anti-human TNF-alpha murine monoclonal antibody with high binding affinity and neutralizing activity
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Song MY, Park SK, Kim CS, Yoo TH, Kim B, Kim MS, Kim YS, Kwag WJ, Lee BK, Baek K
- KMID: 1103586
- Exp Mol Med.
- 2008 Feb;40(1):35-42.
- doi: 10.3858/emm.2008.40.1.35
In order to develop an anti-human TNF-alpha mAb, mice were immunized with recombinant human TNF-alpha. A murine mAb, TSK114, which showed the highest binding activity for human TNF-alpha was selected... -
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- Monoclonal antibody production and characterization for the measurement of plasma high density lipoprotein
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Lee SH, Cho MH
- KMID: 644996
- J Korean Med Sci.
- 1996 Oct;11(5):390-396.
- doi: 10.3346/jkms.1996.11.5.390
We prepared two monoclonal antibodies-A-I30 and A-I4 to HDL apo A-I-with the ultimate goals of expressing and overproducing the valuable immunodiagnostic single chain Fv by phage display libraries in E,... -
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- Production and characterization of monoclonal antibodies to oxidized LDL
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Choi KH, Lee HS, Chung HK
- KMID: 754986
- Exp Mol Med.
- 1998 Mar;30(1):41-45.
Oxidized low density lipoprotein (LDL) seems to take a part in atherogenesis through direct interactions with macrophages, endothelial cells, and smooth muscle cells, and is thought to participate in renal glomerular injury.... -
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- Avidity of serum immunoglobulin G antibodies to Porphyromonas gingivalis in the elderly with chronic periodontitis
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Choi YJ, Lee SW
- KMID: 2446936
- Int J Oral Biol.
- 2019 Mar;44(1):14-19.
- doi: 10.11620/IJOB.2019.44.1.14
The present study aimed at evaluating serum immunoglobulin G (IgG) avidity to Porphyromonas gingivalis in elderly patients with mild and severe chronic periodontitis. The avidity of antibodies against P. gingivalis... -
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- IgG Avidity ELISA Test for Diagnosis of Acute Toxoplasmosis in Humans
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Rahbari AH, Keshavarz , Shojaee S, Mohebali M, Rezaeian M
- KMID: 1384736
- Korean J Parasitol.
- 2012 Jun;50(2):99-102.
- doi: 10.3347/kjp.2012.50.2.99
Serum samples, 100 in the total number, were collected from different laboratories in Tehran, Iran and tested for anti-Toxoplasma specific IgG and IgM antibodies using indirect immunofluorescent antibody test (IFAT).... -
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- Clinical significance of lens culinaris agglutinin-A reactive AFP for differential diagnosis of hepatocellular carcinoma and liver cirrhosis
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Song GA, Kim TO, Song CS, Cho M, Yang US, Ryu SH, Lee SH, Cho BM
- KMID: 2143090
- Korean J Med.
- 1999 Nov;57(5):875-880.
AFP has been the most useful tumor marker of hepatocellular carcinoma (HCC) because AFP is tumor specific and organ specific. However it can be elevated in liver cirrhosis (LC) and chronic hepatitis... -
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- Perturbation of host responses by Porphyromonas gingivalis biofilm
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Jeon WS, Kim SJ, Choi JI
- KMID: 2191765
- J Korean Acad Periodontol.
- 2002 Dec;32(4):827-836.
- doi: 10.5051/jkape.2002.32.4.827
The present study was performed to evaluate how cellular and humoral immune responses were perturbed by immunization of mixed periodontal bacterial biofilms. Each group of mice was immunizared with 1)... -
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- High Expression of Water-Soluble Recombinant Antigenic Domains of Toxoplasma gondii Secretory Organelles
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Yang Z, Ahn HJ, Nam HW
- KMID: 1792197
- Korean J Parasitol.
- 2014 Aug;52(4):367-376.
- doi: 10.3347/kjp.2014.52.4.367
Recombinant antigenic proteins of Toxoplasma gondii are alternative source of antigens which are easily obtainable for serodiagnosis of toxoplasmosis. In this study, highly antigenic secretory organellar proteins, dense granular GRA2... -
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- IgG Avidity Antibodies against Toxoplasma gondii in High Risk Females of Reproductive Age Group in India
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Siddiqui N, Shujatullah F, Khan HM, Rabbani T, Khan PA
- KMID: 1792213
- Korean J Parasitol.
- 2014 Oct;52(5):487-491.
- doi: 10.3347/kjp.2014.52.5.487
Toxoplasma gondii is an obligate intracellular protozoan that is distributed worldwide. Recently, several tests for avidity of Toxoplasma IgG antibodies have been introduced to help discriminate between recently acquired and... -
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