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Update in the Mechanisms of Allergen-Specific Immunotheraphy

Akkoc T, Akdis M, Akdis CA

Allergic diseases represent a complex innate and adoptive immune response to natural environmental allergens with Th2-type T cells and allergen-specific IgE predominance. Allergen-specific immunotherapy is the most effective therapeutic approach...
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Mechanisms of immune tolerance to allergens in children

Kucuksezer UC, Ozdemir C, Akdis M, Akdis CA

Because the prevalence of allergic diseases has significantly increased in recent years, understanding the causes and mechanisms of these disorders is of high importance, and intense investigations are ongoing. Current...
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Particulate Matter 2.5 Causes Deficiency in Barrier Integrity in Human Nasal Epithelial Cells

Xian M, Ma S, Wang K, Lou H, Wang Y, Zhang L, Wang C, Akdis CA

PURPOSE: The effect of air pollution-related particulate matter (PM) on epithelial barrier function and tight junction (TJ) expression in human nasal mucosa has not been studied to date. This study...
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