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Gottron's Acrogeria Syndrome: a case report

Ahn BW, Lee SY, Kim CK, Park CH, Chung YH

  • KMID: 2336026
  • J Korean Orthop Assoc.
  • 1997 Oct;32(5):1380-1386.
Gottron's acrogeria syndrome is a rare genetic disease of unknown etiology with some features suggestive of accelerated aging. The typical clinical presentation consists of premature aging of the skin with...
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Endogenous Stem Cells in Homeostasis and Aging

Lim JE, Son Y

In almost all human tissues and organs, adult stem cells or tissue stem cells are present in a unique location, the so-called stem cell niche or its equivalent, continuously replenishing...
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The Effect of Chemical Peeling on the Dermal Connective Tissue in Facial Wrinkles of Patients with Leprosy

Park HJ, Park HJ, Ahn SY, Kim JP

BACKGROUND: Redundant and wrinkled face is a common finding in patients with long-standing leprosy, which is responsible for the appearance of premature aging. Chemical peeling plays a role in dermal...
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COPD as a Disease of Immunosenescence

Cho WK, Lee CG, Kim LK

Although chronic obstructive pulmonary disease (COPD) is regarded as a chronic inflammatory lung disease, the disease mechanism is still not known. Intriguingly, aging lungs are quite similar to COPD-affected lungs...
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Bilateral Second Branchial Cleft Fistulas: A Case Report

Park YH, Lee JH, Kim JH, Cho SH

  • KMID: 1597361
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 May;48(5):676-679.
The branchiogenic anomalies are common congenital cervical anomalies. They usually arise from an incomplete obliteration of the branchial apparatus during fetal development. These anomalies may be confused with and mistaken...
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DNA damage to human genetic disorders with neurodevelopmental defects

Lee Y, Choi I, Kim J, Kim K

Although some mutations are beneficial and are the driving force behind evolution, it is important to maintain DNA integrity and stability because it contains genetic information. However, in the oxygen-rich...
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Lack of Association between the Klotho Gene and COPD

Kim WJ, Oh YM, Kim TH, Lee JH, Kim EK, Lee JH, Lee SM, Shin TR, Yoon HI, Lim SY, Lee SD

  • KMID: 2319560
  • Tuberc Respir Dis.
  • 2011 Oct;71(4):254-258.
BACKGROUND: Although the aging process and features of chronic obstructive pulmonary disease (COPD) have several similarities, the relationship between aging and COPD pathogenesis remains incompletely understood. The klotho gene was...
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Pathways and genes of DNA double-strand break repair associated with head and neck cancer

Oh JH, Lee DW, Ryu DM

  • KMID: 2118310
  • J Korean Assoc Oral Maxillofac Surg.
  • 2009 Feb;35(1):1-6.
DNA double-strand breaks (DSBs) occur commonly in the all living and in cycling cells. They constitute one of the most severe form of DNA damage, because they affect both strand...
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The Effect of Ultraviolet Irradiation on Epidermal Melanocyte After Sunscreen Application

Choi HM, Kook HI, Park YK

Over-exposure to sunlight may result in sunburn, pigmented skin lesions, solar keratosis, premature aging of skin, or cancer in human skin. Sunscreens protect the structure and function of the human...
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