- O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes
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Park SY, Ryu J, Lee W
- KMID: 1056235
- Exp Mol Med.
- 2005 Jun;37(3):220-229.
It has been known that O-linked beta-N-acetylglucosamine (O-GlcNAc) modification of proteins plays an important role in transcription, translation, nuclear transport and signal transduction. The increased flux of glucose through the... -
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- Adipocyte Signals in Energy Balance and Digestive Diseases
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Chun HJ, Keum B, Uhm CS
- KMID: 782743
- Korean J Gastroenterol.
- 2006 Aug;48(2):67-74.
For the regulation of energy balance in various internal organs including gut, pancreas and liver, visceral adipose tissue and brain perform important sensing and signaling roles via neural and endocrine... -
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- Regulation of leptin gene expression by insulin and growth hormone in mouse adipocytes
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Lee KN, Jeong IC, Lee SJ, Oh SH, Cho MY
- KMID: 1457535
- Exp Mol Med.
- 2001 Dec;33(4):234-239.
The role of leptin in the control of obesity, insulin resistance and type II diabetes has been reported, however, the regulatory mechanism of leptin in animals affected by hormones is... -
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- Butyrate regulates leptin expression through different signaling pathways in adipocytes
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Soliman MM, Ahmed MM, Salah-eldin AE, Abdel-Aal
- KMID: 1365014
- J Vet Sci.
- 2011 Dec;12(4):319-323.
- doi: 10.4142/jvs.2011.12.4.319
Leptin is an adipocytokine that regulates body weight, and maintains energy homeostasis by promoting reduced food intake and increasing energy expenditure. Leptin expression and secretion is regulated by various factors... -
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