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Control Mechanisms of Ovulation by Pituitary Adenylate Cyclase-Activating Polypeptide

Lee YI, Kim HC, Kim MY, Chun SY

  • KMID: 2085168
  • Korean J Fertil Steril.
  • 2005 Jun;32(2):101-112.
No abstract available.
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Vasoactive Intestinal Peptide/Pituitary Adenylate Cyclase Activating Peptide Receptor Subtypes in Neuroblastoma, Stomach Cancer

Park SK, Park SJ, Kim HM, Jeong JY, Hur MK

  • KMID: 2278217
  • Korean J Pediatr Hematol Oncol.
  • 2001 Apr;8(1):51-57.
PURPOSE: We analyzed the expression of vasoactive intestinal peptide (VIP), pituitary adenylate cyclase activating peptide (PACAP), VIP receptor 1 (VIPR1), VIP receptor 2 (VIPR 2) and PACAP receptor (PACAPR) genes...
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Stimulation by EGF, bFGF and GnRH of Ovarian Pituitary Adenylate Cyclase-Activating Polypeptide Gene Expression in Cultured Rat Preovulatory Follicles

Lee YI, Park JY, Park JH, Park HJ, Park HJ, Bae JA, Chun SY

  • KMID: 1979138
  • Korean J Fertil Steril.
  • 2001 Dec;28(4):271-278.
No abstract available.
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Control Mechanisms of Ovarian Follicle Development by Follicle Stimulating Hormone and Pituitary Adenylate Cyclase-activating Polypeptide

Lee YI, Shin JO, Kim MY, Chun SY

  • KMID: 1511386
  • Korean J Fertil Steril.
  • 2006 Mar;33(1):15-24.
OBJECTIVE: Pituitary adenylate cyclase-activating polypeptide (PACAP), a novel hypothalamic neuropeptide, has been suggested to play a role in ovarian folliculogenesis. The present study evaluated the effect of PACAP on the...
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Role of Pituitary Adenylate Cyclase Activating Polypeptide-(1-27) in the Clitorial Cavernosum Smooth Muscle

Kang MH, Min JK, Lee HK, Park YK, Park JK

  • KMID: 2292356
  • Korean J Urol.
  • 2001 Mar;42(3):341-346.
PURPOSE: Pituitary adenylate cyclase-activating polypeptide (PACAP) showed the relaxant effect and distribution patterns in the penile corpus cavernosum. We investigated the presence, distribution, and effects of PACAP-(1-27) in the clitoral...
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Expression of Neuropeptides and Their Receptors in Melasma

Lee HJ, Bak H, Chang SE, Choi JH, Kim MN, Kim BJ

  • KMID: 2248294
  • Korean J Dermatol.
  • 2008 May;46(5):627-632.
BACKGROUND: The pathogenesis of melasma has not yet been clearly demonstrated. But, clinical manifestations such as remarkable lesional symmetry and the distribution related to trigeminal nerves, suggest that the neural...
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Multi-facet expressions of adenylate cyclase isoforms in B16-F10 melanoma cells differentiated by forskolin treatment

Cho DH, Bae CD, Juhnn YS

  • KMID: 755106
  • Exp Mol Med.
  • 2000 Dec;32(4):235-242.
The terminal differentiation of malignant melanoma cells is known to be induced by activating cAMP signaling pathway with alpha-MSH or cAMP analogues. However, sustained activation of cAMP signaling...
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Expression of pituitary adenylate cyclase activating polypeptide and its type I receptor mRNAs in human placenta

Koh PO, Won CK, Noh HS, Cho GJ, Choi WS

  • KMID: 1106068
  • J Vet Sci.
  • 2005 Mar;6(1):1-5.
Pituitary adenylate cyclase activating polypeptide (PACAP) was first isolated from ovine hypothalamus and was known to stimulate the release of growth factor in various cells. Recently, we reported the cellular...
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Regulation of Prolactin Gene Expression by Hypothalamic Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) in the Female Rat Pituitary Gland

Kim YI, Ha TY, Kim ES, Nam-Goong , O'Dorisio , Hur MK, Park SK

  • KMID: 1837622
  • J Korean Soc Endocrinol.
  • 2004 Apr;19(2):152-164.
BACKGROUND: Pituitary adenylate cyclase-activating polypeptide (PACAP) plays the role of a hypophysiotropic factor, which regulates the synthesis and secretion of pituitary hormones through the hypothalamo-hypophysial portal system. No clear evidence...
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Pituitary Adenylate Cyclase-activating Polypeptide Inhibits Pacemaker Activity of Colonic Interstitial Cells of Cajal

Wu MJ, Kee KH, Na J, Kim SW, Bae Y, Shin DH, Choi S, Jun JY, Jeong HS, Park JS

This study aimed to investigate the effect of pituitary adenylate cyclase-activating peptide (PACAP) on the pacemaker activity of interstitial cells of Cajal (ICC) in mouse colon and to identify the...
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SR144528 as Inverse Agonist of CB2 Cannabinoid Receptor

Rhee MH, Kim SK

  • KMID: 1095119
  • J Vet Sci.
  • 2002 Sep;3(3):179-184.
It is now well established that several G protein- coupled receptors can signal without agonist stimulation (constitutive receptors). Inverse agonists have been shown to inhibit the activity of such constitutive...
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A Case of Fibrous Dysplasia Confined Bilateral Middle Turbinates

Kim JM, Jun KH, Lee JH, Choi KH

Fibrous dysplasia, a rare bony disease, is characterized by substitution of normal bone with immature tissue embedded in a fibrous stroma. The localization of fibrous dysplasia only at the middle...
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Interaction of Pituitary Adenylate Cyclase-Activating Polypeptide and Angiotensin II on Aldosterone Production in Human Adrenocortical H295R Cells

Kim SY, Kim SW, Cho YM, Park DJ, Shin CS, Park KS, Cho BY, Lee HK

  • KMID: 2200306
  • J Korean Soc Endocrinol.
  • 2003 Jun;18(3):272-282.
BACKGROUND: Evidence is accumulating that aldosterone secretion can be regulated in a paracrine and/or an autocrine manner by several neuropeptides locally released within the adrenal gland. Among neuropeptides, pituitary adenylate...
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Mechanism of pituitary adenylate cyclase-activating polypeptide-induced inhibition on catecholamine secretion evoked by cholinergic stimulation and membrane depolarization in the rat adrenal gland

Lim DY, Kang JW, Kim YJ

  • KMID: 2285228
  • Korean J Physiol Pharmacol.
  • 1999 Jun;3(3):339-350.
The present study was attempted to examine the effect of pituitary adenylate cyclase-activating polypeptide (PACAP) on catecholamine (CA) secretion evoked by cholinergic stimulation, membrane depolarization and calcium mobilization from the isolated perfused rat...
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Effect of adenylate cyclase inhibitor and protein kinase C inhibitor on GnRH-induced LH release and LH beta subunit biosynthesis in rat anterior pituitary cells

Kim C, Park D, Ryu K

According to our previous studies together with others, GnRH, a hypothalamic decapeptide, has been known to be a major regulator for LH release and its subunit biosynthesis in anterior pituitary...
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Two cases of Ticlopidine-induced neutropenia in patients with cardiovascular disease

Chae GS, Yoo HS, Jee JH, Lee JM, Ahn JS, Lee JA, Park YS, Doo YC, Han KR, Oh DJ, Rhim CY

Ticlopidine is an antiplatelet agent used as a drug to prevent the recurrence of cerebral infarction or ischemic heart disease. Close attention has recently been paid to the superiority of...
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Adaptation of cAMP signaling system in SH-SY5Y neuroblastoma cells following expression of a constitutively active stimulatory G protein alpha, Q227L Gsalpha

Jang IS, Juhnn YS

  • KMID: 755116
  • Exp Mol Med.
  • 2001 Mar;33(1):37-45.
Heterotrimeric GTP-binding proteins (G protein) are known to participate in the transduction of signals from ligand activated receptors to effector molecules to elicit cellular responses. Sustained activation of cAMP-G protein...
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Functional Role of Serine Residues of Transmembrane Dopamin VII in Signal Transduction of CB2 Cannabinoid Receptor

Rhee MH

  • KMID: 1095120
  • J Vet Sci.
  • 2002 Sep;3(3):185-191.
Using site-directed mutagenesis technique, I have replaced serine 285 and serine 292 with the alanine, and assessed the binding of agonist and signaling such as the inhibition of adenylyl cyclase...
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Altered Renal Expression of Aquaporin-2 Water Channels in Rats with Experimental Two-Kidney, One Clip Hypertension

Lee JU, Oh YW, Kim SW

The present study was aimed at examining the regulation of aquaporin (AQP)-2 water channels in the kidney in two-kidney, one clip (2K1C) hypertension. Rats were made 2K1C hypertensive for 6...
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DNA methylation in human papillomavirus-infected cervical cells is elevated in high-grade squamous intraepithelial lesions and cancer

Kim MK, Lee IH, Lee KH, Lee YK, So KA, Hong SR, Hwang CS, Kee MK, Rhee JE, Kang C, Hur SY, Park JS, Kim TJ

OBJECTIVE: DNA methylation has been shown to be a potential biomarker for early cancer detection. The aim of this study was to evaluate DNA methylation profiles according to liquid-based Pap...
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