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Differential Expression of Activating Transcription Factor-2 and c-Jun in the Immature and Adult Rat Hippocampus Following Lithium-Pilocarpine Induced Status Epilepticus

Han SR, Shin C, Park S, Rhyu S, Park J, Kim YI

  • KMID: 2396060
  • Yonsei Med J.
  • 2009 Apr;50(2):200-205.
PURPOSE: Lithium-pilocarpine induced status epilepticus (LPSE) causes selective and age-dependent neuronal death, although the mechanism of maturation-related injury has not yet been clarified. The activating transcription factor-2 (ATF-2) protein is...
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Differential gene expression pattern in brains of acrylamide-administered mice

Han CH

  • KMID: 1435820
  • Korean J Vet Res.
  • 2012 Jun;52(2):99-104.
The present study was performed to evaluate the relationship between the neurotoxicity of acrylamide and the differential gene expression pattern in mice. Both locomotor test and rota-rod test showed that...
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Transcription of the protein kinase C-delta gene is activated by JNK through c-Jun and ATF2 in response to the anticancer agent doxorubicin

Min BW, Kim CG, Ko J, Lim Y, Lee YH, Shin SY

Expression of protein kinase C-delta (PKC delta) is up-regulated by apoptosis-inducing stimuli. However, very little is known about the signaling pathways that control PKC delta gene transcription. In the present...
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Microarray Analysis of Short Heterodimer Partner (SHP)-induced Changes in Gene Expression in INS-1 Cells

Jung ED, Lee JH, Jang WG, Kim JG, Kim BW, Lee IK

BACKGROUND: Nuclear receptors are involved in the cell growth, development, differentiation, and metabolism. The orphan nuclear receptor SHP which lacks a DNA-binding domain is a negative regulator of nuclear receptor...
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Wnt5a stimulates chemotactic migration and chemokine production in human neutrophils

Jung YS, Lee HY, Kim SD, Park JS, Kim JK, Suh PG, Bae YS

  • KMID: 2154246
  • Exp Mol Med.
  • 2013 Jun;45(6):e27.
Wnt5a is a ligand that activates the noncanonical Wnt signaling pathways (beta-catenin-independent pathways). Human neutrophils expressed several Wnt5a receptors, such as Frizzled 2, 5 and 8. Stimulation of human neutrophils...
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