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Stimulatory heterotrimeric G protein augments gamma ray-induced apoptosis by up-regulation of Bak expression via CREB and AP-1 in H1299 human lung cancer cells

Choi YJ, Kim SY, Oh JM, Juhnn YS

Stimulatory heterotrimeric GTP-binding proteins (Gs protein) stimulate cAMP generation in response to various signals, and modulate various cellular phenomena such as proliferation and apoptosis. This study aimed to investigate the...
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Cytotoxicity of gamma-ray in rat immature hippocampal neurons

Yang M, Song MS, Kim SH, Kim JC, Kim JS, Shin T, Moon C

This in vitro study evaluated the detrimental effect of acute gamma (gamma)-irradiation on rat immature hippocampal neurons. Rat immature hippocampal neurons (0.5 day in vitro) were irradiated with 0~4 Gy...
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Adaptive response to ionizing radiation induced by low dose of gamma ray in human hepatoma cell lines

Seong J, Kim GE

When cells are exposed to a low dose of a mutagenic or clastogenic agent, they often become less sensitive to the effects of a higher dose administered subsequently. Such adaptive...
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