Korean J Radiol.  2011 Feb;12(1):1-14. 10.3348/kjr.2011.12.1.1.

Ultrasonography and the Ultrasound-Based Management of Thyroid Nodules: Consensus Statement and Recommendations

Affiliations
  • 1Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul 143-914, Korea. mdmoonwj@naver.com
  • 2Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Korea.
  • 3Department of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul 137-701, Korea.
  • 4Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, Korea.
  • 5Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul 120-752, Korea.
  • 6Department of Radiology, Dong-A University Medical Center, Dong-A University College of Medicine, Busan 602-715, Korea.
  • 7Department of Radiology, Ansan Hospital, Korea University School of Medicine, Gyeonggi-do 425-707, Korea.
  • 8Human Medical Imaging & Intervention Center, Seoul 137-902, Korea.
  • 9Healthcare System Gangnam Center, Seoul National University Hospital, Seoul 135-984, Korea.
  • 10Department of Radiology, Hanyang University Hospital, Hanyang University College of Medicine, Seoul 133-792, Korea.
  • 11Department of Radiology, SMG-SNU Boramae Medical Center, Seoul National University College of Medicine, Seoul 156-707, Korea.

Abstract

The detection of thyroid nodules has become more common with the widespread use of ultrasonography (US). US is the mainstay for detecting and making the differential diagnosis of thyroid nodules as well as for providing guidance for a biopsy. The Task Force on Thyroid Nodules of the Korean Society of Thyroid Radiology has developed recommendations for the US diagnosis and US-based management of thyroid nodules. The review and recommendations in this report have been based on a comprehensive analysis of the current literature, the results of multicenter studies and from the consensus of experts.

Keyword

Thyroid, US; Thyroid, neoplasms; Thyroid, aspiration biopsy

MeSH Terms

Biopsy, Fine-Needle
Diagnosis, Differential
Humans
Thyroid Gland/pathology/ultrasonography
Thyroid Neoplasms/pathology/ultrasonography
Thyroid Nodule/pathology/*ultrasonography
Ultrasonography, Interventional

Figure

  • Fig. 1 Internal content of thyroid nodules. A. Solid B. Predominantly solid C. Predominantly cystic D. Cystic

  • Fig. 2 US findings of spongiform appearance are shown Transverse US image of benign nodular hyperplasia shows well-defined smooth isoechoic mass with a spongiform appearance (arrows).

  • Fig. 3 Shape of thyroid nodules. Corresponding schematic drawings are shown in upper panel. A. Ovoid-to-round shape B. Taller-than-wide shape C. Irregular shape

  • Fig. 4 Margin of thyroid nodules. A. Smooth margin B. Spiculated or microlobulated margin (arrow) C. Ill-defined margin (arrows)

  • Fig. 5 Echogenicity of thyroid nodules. A. Marked hypoechogenicity of nodule is shown. Note more hypoechoic nature of nodule (arrow) as compared to that of strap muscles (asterisk). B. Hypoechogenicity of nodule (arrows) C. Isoechogenicity of nodule (arrows) D. Hyperechogenicity of nodule (arrow)

  • Fig. 6 Calcifications of thyroid nodules. A. Microcalcification within nodule as echogenic focus B. Macrocalcification (arrow) in center of nodule (white triangles) C. Rim calcification in small nodule (calipers).

  • Fig. 7 US elastography of thyroid nodules. A. Elastography shows nodule with hard consistency as blue relative to green background. B. Longitudinal US image shows same nodule with suspicious malignant US features. Nodule was proven to be papillary carcinoma.

  • Fig. 8 Flowchart for strategy for follow-up US and US-guided fine needle aspiration (USFNA) biopsy according to US findings and cytology results of thyroid nodules. Dotted arrow means that surgery is not strongly recommended, but it can be considered according to individual situations. AUS = atypia of undetermined significance, FLUS = follicular lesion of undetermined significance.


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