Korean J Gastroenterol.  2008 Feb;51(2):137-141.

A Case of Steroid Resistant Autoimmune Hemolytic Anemia in Ulcerative Colitis

• Choi HJ
• Hong SJ
• Kim YJ
• Ko BM
• Lee MS
• Shim CS
• Kim HJ
• Hong DS

Abstract

Autoimmunity is thought to play a central role in the pathogenesis of inflammatory bowel disease and associated extraintestinal manifestations. Autoimmune hemolytic anemia associated with ulcerative colitis is a rare occurrence. No more than 50 cases have been described in the international literatures, and only 2 cases reported in Korea. A 29-year-old woman who was diagnosed as ulcerative colitis two years ago was complicated with autoimmune hemolytic anemia, and did not respond to steroid therapy. Ultimately, total colectomy and splenectomy were carried out for the treatment of ulcerative colitis and hemolytic anemia. After the operation, anemia was resolved. We present the case with a review of literature.

Keyword

Ulcerative colitis; Autoimmune hemolytic anemia

MeSH Terms

Adult
Anemia, Hemolytic, Autoimmune/*diagnosis/drug therapy/etiology
Colectomy
Colitis, Ulcerative/complications/*diagnosis/pathology
Drug Resistance
Female
Humans
Splenectomy
Steroids/therapeutic use