Korean J Gastroenterol.  2007 Jun;49(6):356-363.

Endoscopic Submucosal Dissection for Early Gastric Cancer and Gastric Adenoma

• Jang JS
• Lee EJ
• Lee SW
• Lee JH
• Roh MH
• Han SY
• Choi SR
• Jeong JS

Abstract

BACKGROUND/AIMS: Endoscopic Submucosal Dissection (ESD) is a new endoscopic mucosal resection (EMR) technique which enables en bloc resection even in large and depressed lesions. The aims of this study were to assess the therapeutic efficacy and the safety of ESD in gastric adenoma and in early gastric cancer (EGC). METHODS: We analyzed 101 lesions in 101 patients. ESD with insulated-tipped (IT) knife were performed in 52 adenomas and 49 EGCs from January 2003 to December 2005 in Dong-A University Hospital. RESULTS: The mean size of the lesion was 2.58 cm (0.7-4.5 cm). En bloc resection rate was 90.1% which was influenced by size (p>0.05). Complete resection rate was 83.2% even in large or in malignant tumors (p>0.05). Bleeding after ESD occurred in 41.6%. Tumor recurrence rate was 2.0%. CONCLUSIONS: ESD with IT knife is effective for the treatment of EGC and gastric adenoma even in large or in malignant lesions without definite increased risk of complications.

Keyword

Endoscopic submucosal dissection; Early gastric cancer; Adenoma

MeSH Terms

Adenoma/pathology/*surgery
Adult
Aged
Dissection/instrumentation
Female
Gastric Mucosa/pathology/*surgery
*Gastroscopy
Humans
Male
Middle Aged
Neoplasm Staging
Retrospective Studies
Stomach Neoplasms/pathology/*surgery
Surgical Procedures, Minimally Invasive