Korean J Intern Med.  2003 Dec;18(4):255-259.

Loffler's Syndrome Associated with Clonorchis Sinensis Infestation

Affiliations
  • 1Department of Internal Medicine, Inje University College of Medicine, Seoul, Korea. pulho@korea.com

Abstract

In 1932, Loffler described a syndrome of self-limiting, transient pulmonary infiltrates associated with peripheral blood eosinophilia and mild pulmonary symptoms. A number of conditions are related to pulmonary eosinophilia or pulmonary infiltration with eosinophilia. Especially, parasitic infestations are often related to pulmonary eosinophilia, but only two cases associated with Clonorchis sinensis have been anecdotally reported in English literature. Here we report a case of migrating pulmonary eosniophilic infiltrations associated with Clonorchis sinensis that was successfully treated with praziquantel. Clonorchiasis should be considered in patients with marked eosinophilia and pulmonary infiltrations.

Keyword

Loffler's syndrome; Clonorchis sinensis; Pulmonary eosinophilia; Eosinophilic pneumonia; Praziquantel

MeSH Terms

Animals
Biopsy
Clonorchiasis/*complications/*diagnosis
Clonorchis sinensis/*isolation & purification
Human
Male
Middle Aged
Pulmonary Eosinophilia/*etiology/pathology/radiography
Syndrome
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