Korean J Intern Med.
2000 Jul;15(2):131-134.
Secondary renal amyloidosis in adult onset Still's disease: case report and review of the literature
- Affiliations
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- 1Department of Rheumatology, Tong-Inchon Ghil Hospital, Gachon Medical School, Inchon, Korea.
- 2The Hospital for Rheumatic Diseases, Department of Internal Medicine, Hanyang University Medical Center, Seoul, Korea.
- 3Department of Pathology, Hanyang University Medical Center, Seoul, Korea.
Abstract
- We report a 25-year-old Korean woman with Adult onset Still's disease (AOSD) presented with renal amyloidosis, which had developed four years after disease onset. We successfully treated her with prednisolone, colchicine and cyclophosphamide. A review of the literature uncovered about 10 cases, most of which were treated by various regimens that resulted in poor outcomes. Renal amyloidosis should be suspected in patients with AOSD who have unexplained proteinuria. Although the mechanism of renal amyloid deposition is not well known, earlier histopathologic diagnosis and choice of regimen may affect prognosis.
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