Korean J Intern Med.  1998 Jul;13(2):143-146.

A case of CMV disease of the jejunum in a patient with non-Hodgkin's lymphoma

• Han KJ
• Jung IS
• Kim CK
• Park SK
• Kim DW
• Baick SH
• Won JH
• Hong DS
• Hwang SD
• Moon C
• Park HS

Abstract

CMV infection may occur anywhere in the gastrointestinal tract. Among the small intestine, ileum is the most common site of CMV disease and infection of jejunum is a rare one in patients with CMV gastroenteritis. Although rare, the reason why the recognition of this diagnosis is important is that it cause the lethal hemorrhage and perforation of gastrointestinal tract when its diagnosis and treatment was delayed. Rapid diagnosis are able to using the immunohistochemical stain in shell vial culture of infected specimen or peripheral neutrophils preparation in viremic patients within 8 to 36 hours. The treatment of choice is antiviral agent or surgical resection. We experienced a case of CMV disease of jejunum in patient with non-Hodgkin's lymphoma who showed severe ulceration in jejunum and massive intestinal hemorrhage, and he survived after successful treatment with segmental resection of jejunum and intravenous ganciclovir.

MeSH Terms

Adult
Antiviral Agents/therapeutic use
Cytomegalovirus Infections/drug therapy
Cytomegalovirus Infections/diagnosis
Cytomegalovirus Infections/complications*
Disease-Free Survival
Enteritis/virology
Enteritis/surgery
Enteritis/complications
Ganciclovir/therapeutic use
Gastrointestinal Hemorrhage/therapy
Gastrointestinal Hemorrhage/etiology*
Gastrointestinal Hemorrhage/diagnosis
Human
Jejunal Diseases/virology
Jejunal Diseases/surgery
Jejunal Diseases/complications*
Lymphoma, Non-Hodgkin/drug therapy
Lymphoma, Non-Hodgkin/diagnosis
Lymphoma, Non-Hodgkin/complications*
Male
Opportunistic Infections/drug therapy
Opportunistic Infections/diagnosis
Opportunistic Infections/complications*
Substances: Ganciclovir
Substances: Antiviral Agents