Korean J Radiol.  2002 Sep;3(3):158-162. 10.3348/kjr.2002.3.3.158.

Brain MRI Findings of Carbon Disulfide Poisoning

Affiliations
  • 1Department of Radiology, Wonjin Green Hospital, Kangwon-do, Korea. sskim@kangwon.ac.kr
  • 2Department of Radiology, Kangwon National University College of Medicine, Kangwon-do, Korea.
  • 3Department of Environmental Health, School of Public Health, Seoul National University, Seoul, Korea.
  • 4Department of Occupational Medicine, Wonjin Green Hospital, Kangwon-do, Korea.
  • 5Department of Family Medicine, Wonjin Green Hospital, Kangwon-do, Korea.

Abstract


OBJECTIVE
To evaluate the findings of brain MRI in patients with carbon disulfide poisoning.
MATERIALS AND METHODS
Ninety-one patients who had suffered carbon disulfide poisoning [male:female=87:4; age, 32-74 (mean 53.3) years] were included in this study. To determine the extent of white matter hyperintensity (Grade 0-V) and lacunar infarction, T2-weighted MR imaging of the brain was performed.
RESULTS
T2-weighted images depicted white matter hyperintensity in 70 patients (76.9%) and lacunar infarcts in 27 (29.7%).
CONCLUSION
In these patients, the prevalent findings at T2-weighted MR imaging of the brain were white matter hyperintensity and lacunar infarcts. Disturbance of the cardiovascular system by carbon disulfide might account for these results.

Keyword

Brain, poisoning; Brain, MR

MeSH Terms

Adult
Aged
Brain/*drug effects/*pathology
Brain Infarction/*pathology
Carbon Disulfide/*poisoning
Female
Human
Magnetic Resonance Imaging
Male
Middle Age
Retrospective Studies

Figure

  • Fig. 1 A 34-year-old man exposed to carbon disulfide for nine years, but with no accompanying disease. T1- (A) and T2-weighted (B) axial images depict between 10 and 20 grade-II focal white matter lesions in the fontal lobe.

  • Fig. 2 A 64-year-old man with hypertension after exposure to carbon disulfide for 13 years. T2-weighted axial image shows a grade-V, diffuse, confluent white matter lesion in the centrum semiovale.

  • Fig. 3 A 58-year-old man exposed to carbon disulfide for 15 years, but with no accompanying disease. T1- (A) and T2-weighted (B) images indicate that multifocal lacunar infarcts are present in the basal ganglia and genu of the corpus callosum.


Cited by  1 articles

Occupational Neurologic Disorders in Korea
Yangho Kim, Kyoung Sook Jeong, Yong-Hun Yun, Myoung-Soon Oh
J Clin Neurol. 2010;6(2):64-72.    doi: 10.3988/jcn.2010.6.2.64.


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