Yonsei Med J.  2003 Jun;44(3):534-538. 10.3349/ymj.2003.44.3.534.

Autoimmune Pancreatitis with Effective Steroid Therapy

  • 1Department of Internal Medicine, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea. sysong@yumc.yonsei.ac.kr
  • 2Department of Diagnostic Radiology, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
  • 4Institute of Gastroenterology, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.


Autoimmune pancreatitis has recently been described as a clinical entity that causes chronic pancreatitis. This unique form of chronic pancreatitis is characterized by minimal attacks of abdominal pain, irregular narrowing of the pancreatic duct, and a diffuse enlargement of the pancreas. Autoimmune pancreatitis is associated with hypergammaglobulinemia. In addition, there is histological evidence of lymphoplasmacytic inflammation, the occasional coexistence of other autoimmune diseases, and has a favorable response to glucocorticoid treatment. Recently autoimmune pancreatitis has been increasingly reported particularly in Japan. We report two patients with autoimmune pancreatitis who were treated successfully with corticosteroid therapy.


Pancreatitis; autoimmunity; glucocorticoids

MeSH Terms

Anti-Inflammatory Agents/*therapeutic use
Autoimmune Diseases/*drug therapy/pathology/radiography
Cholangiopancreatography, Endoscopic Retrograde
Chronic Disease
Middle Aged
Pancreatitis/*drug therapy/pathology/radiography
Prednisolone/*therapeutic use
Tomography, X-Ray Computed
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