J Korean Med Sci.  2002 Dec;17(6):845-848. 10.3346/jkms.2002.17.6.845.

Mixed Tumor of the Vagina: A Case Report

Affiliations
  • 1Department of Pathology, Pusan Paik Hospital, College of Medicine, Inje University, Busan, Korea. kingkang@intizen.com

Abstract

We report a case of mixed tumor arising in the lower vaginal wall. The patient was a 20-yr-old nullipararous woman. The tumor was relatively well-defined with expansile margin, and showed solid sheets or fascicles of stromal-type spindle cells and ovoid epithelial cells with sparsely scattered nests of mature squamous epithelium and glands lined by mucinous epithelium. Cellular atypia was not conspicuous, however, mitosis was counted upto 6 per 10 high power fields. We examined this tumor immunohistochemically and ultrastructurally and reviewed the articles to identify the histogenesis. Positive reaction for vimenin and cytokeratin of stromaltype spindle cells and presence of desmosome-like structures and tonofilaments on electron microscopic examination suggested the epithelial origin of the stromaltype spindle cells.

Keyword

Vagina; Mixed Tumor; Pleomorphic Adenoma

MeSH Terms

Adult
Female
Humans
Immunohistochemistry
Keratins/biosynthesis
Microscopy, Electron
Mitosis
Mixed Tumor, Malignant/*diagnosis/pathology/ultrastructure
Vagina/*pathology
Vaginal Neoplasms/*diagnosis/pathology/ultrastructure
Vimentin/biosynthesis
Full Text Links
  • JKMS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr