Blood Res.  2025;60:2. 10.1007/s44313-024-00052-4.

Pseudo Chediak‑Higashi anomaly in a diffuse large B‑cell lymphoma with hemophagocytic lymphohistiocytosis

• Yi B
• Zeng M

• KMID: 2564326
• DOI: http://doi.org/10.1007/s44313-024-00052-4

Keyword

Pseudo Chediak-Higashi; Diffuse large B cell lymphoma; Hemophagocytic lymphohistiocytosis

Figure

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  Fig. 1 A-D A few vacuolated pink inclusions of different sizes were found in the cytoplasm of lymphoma cells in bone marrow aspirate (black arrow, Wright–Giemsa staining;×1000).These inclusions, known as pseudo-Chédiak-Higashi anomalies, are rare in mature B-cell tumors and draw attention to the unique morphological characteristics of these cells. E These inclusions were negative for myeloperoxidase staining (black arrow, POX staining;×1000). F These inclusions were positive for periodic acid-Schiff staining (black arrow, PAS staining;×1000)

Reference

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