Gut Liver.  2024 Mar;18(2):218-221. 10.5009/gnl230125.

Challenges in Implementing Endoscopic Resection for T2 Colorectal Cancer

Affiliations
  • 1Digestive Disease Center, Showa University Northern Yokohama Hospital, Yokohama, Japan
  • 2Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore
  • 3Yong Loo Lin School of Medicine, National University of Singapore, Singapore
  • 4Department of Surgery, National University Hospital, Singapore

Abstract

The current standard treatment for muscularis propria-invasive (T2) colorectal cancer is surgical colectomy with lymph node dissection. With the advent of new endoscopic resection techniques, such as endoscopic full-thickness resection or endoscopic intermuscular dissection, T2 colorectal cancer, with metastasis to 20%-25% of the dissected lymph nodes, may be the next candidate for endoscopic resection following submucosal-invasive (T1) colorectal cancer. We present a novel endoscopic treatment strategy for T2 colorectal cancer and suggest further study to establish evidence on oncologic and endoscopic technical safety for its clinical implementation.

Keyword

Endoscopic full-thickness resection; Lymph node metastasis; Treatment strategy; T2 colorectal cancer
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