J Pathol Transl Med.  2024 Jan;58(1):40-42. 10.4132/jptm.2023.11.05.

Comment on “A stepwise approach to fine needle aspiration cytology of lymph nodes”

• Maffei E
• Ciliberti V
• Zeppa P
• Caputo A

• KMID: 2550500
• DOI: http://doi.org/10.4132/jptm.2023.11.05

Figure

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  Fig. 1. Three cases of atypical lymphoid cells solved by ancillary techniques. (A) Cervical lymph node fine needle aspiration cytology (LNFNAC) in a 38-year-old woman. (B) Axillary LN-FNAC in a 62-year-old woman. (C) Cervical lymph node FNAC in a 28-year-old man. Cases A and C were found to be polyclonal on flow cytometry; additionally, in case C, Epstein-Barr virus (EBV)–encoded RNA stain positivity demonstrated EBV infection. Both the lymph nodes shrunk at follow-up. In case B, flow cytometry showed kappa light chain restriction and CD5/CD19 co-expression. Cytological and phenotypical features were indicative of a diffuse, small lymphocytic lymphoma. Histological control demonstrated a small lymphocytic lymphoma/chronic lymphocytic leukemia (A–C, Diff-Quik stain).

Reference

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