Ann Child Neurol.  2024 Jan;32(1):1-7. 10.26815/acn.2023.00241.

Correlation between Diagnostic Magnetic Resonance Imaging Criteria and Cerebrospinal Fluid Pressure in Pediatric Idiopathic Intracranial Hypertension

• Beizaei B
• Toosi FS
• Shahmoradi Y
• Akhondian J
• Ashrafzadeh F
• Toosi MB
• Imannezhad S
• Kooshki A
• Nejad EH
• Payandeh A
• Tavakkolizadeh N
• Ghalibaf AM
• Hashemi N

• KMID: 2549713
• DOI: http://doi.org/10.26815/acn.2023.00241

Abstract

Purpose
Idiopathic intracranial hypertension (IIH) is a clinical syndrome that mimics brain tumors with increased intracranial pressure. The present study is designed to investigate the diagnostic criteria of magnetic resonance imaging (MRI) and the severity of cerebrospinal fluid (CSF) pressure to understand the relationship and frequency of these criteria with the level of CSF pressure.
Methods
The present cross-sectional study was conducted on children diagnosed with IIH between the years 2011 and 2020, who were admitted to the pediatric neurology department of Ghaem Hospital, Mashhad, Iran. Clinical manifestations and imaging findings of the patients were recorded through a checklist.
Results
Forty-nine patients were included in the study; 27 (55.1%) were male, and 22 (44.9%) were female. The average CSF pressure was 40.64±20.63 cmH₂O. The mean diameter distension of the perioptic subarachnoid space was 6.02±1.21 mm. Six (10.8%) patients had unilateral transverse sinus stenosis with an average CSF pressure of 20.47±36.80 cmH₂O and 11 (21.4%) patients had bilateral transverse sinus stenosis with an average pressure of 48.22±21.04 cmH₂O. In 22 (44.89%) patients, flattening of the posterior globe with the CSF pressure of 48.80±17.94 cmH₂O was reported. Twenty-four (49%) patients had optic nerve tortuosity, with an average CSF pressure of 46.52±20.33 cmH₂O. Among the diagnostic criteria, the pressure had a significant relationship with the flattening of the posterior globe (P<0.022).
Conclusion
Since MRI is a non-invasive method for examining IIH, the findings of this study may aid in diagnosing and monitoring these patients.

Keyword

Magnetic resonance imaging; Cerebrospinal fluid; Pseudotumor cerebri; Pediatrics